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pro vyhledávání: '"M. Manji"'
Akademický článek
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Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74243 (2013)
Animal models that recapitulate human disease are proving to be an invaluable tool in the identification of novel disease-associated genes. These models can improve our understanding of the complex genetic mechanisms involved in disease and provide a
Externí odkaz:
https://doaj.org/article/6e3d9a5751d549ecb449b3bb60e32efc
Autor:
Kerry A Miller, Louise H Williams, Elizabeth Rose, Michael Kuiper, Hans-Henrik M Dahl, Shehnaaz S M Manji
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51284 (2012)
Human MYO7A mutations can cause a variety of conditions involving the inner ear. These include dominant and recessive non-syndromic hearing loss and syndromic conditions such as Usher syndrome. Mouse models of deafness allow us to investigate functio
Externí odkaz:
https://doaj.org/article/d7055fa0af4547088767169f6c5fc143
Autor:
Shehnaaz S M Manji, Louise H Williams, Kerry A Miller, Lisa M Ooms, Melanie Bahlo, Christina A Mitchell, Hans-Henrik M Dahl
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17607 (2011)
Hearing impairment is the most common sensory impairment in humans, affecting 1:1,000 births. We have identified an ENU generated mouse mutant, Mozart, with recessively inherited, non-syndromic progressive hearing loss caused by a mutation in the syn
Externí odkaz:
https://doaj.org/article/66b3bb9bee1a448193c836fec6c9afef
Akademický článek
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Publikováno v:
Malaria Research and Treatment, Vol 2019 (2019)
Malaria Research and Treatment
Malaria Research and Treatment
Introduction. Falciparum malaria still remains as a major cause of morbidity and mortality worldwide. Acute kidney injury is a known complication of malaria, and it is reported to occur in up to 40% of adult patients with severe falciparum malaria in
Publikováno v:
Trauma. 12:149-153
Hypotensive resuscitation in the trauma setting can be defined as deliberately allowing blood pressure to remain below normal until any active bleeding has been controlled. The dangers of aggressive fluid resuscitation in trauma were recognised as lo
Akademický článek
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Publikováno v:
Anaesthesia. 61:260-263
To ensure that sedative agents in the intensive care unit are used for maximum benefit, a guideline that promotes the accurate and continuous assessment of patients' needs is indicated. This observational 24-month prospective study investigated the e
Publikováno v:
Anaesthesia. 56:988-1002
Pre-operative optimisation of high-risk patients undergoing major elective surgery has been shown to decrease peri-operative morbidity and mortality. It is also cost effective because of the resulting decrease in postoperative complications. A questi