Zobrazeno 1 - 10
of 38
pro vyhledávání: '"M. Mangrum"'
Autor:
Mikayla M. Mangrum, Amanda K. Vogel, Andrew S. Wagner, Ainsley E. King, Jian Miao, Yue Zhou, Elise K. Phillips, Brian M. Peters, Todd B. Reynolds
Publikováno v:
mSphere, Vol 9, Iss 9 (2024)
ABSTRACT The uridine derivatives UDP-glucose and UDP-N-acetylglucosamine are important for cell wall construction as they are the precursors for the synthesis of β-1,3-glucan and chitin, respectively. Previous studies have demonstrated attenuated vi
Externí odkaz:
https://doaj.org/article/02c2f50c03854cf991f9db9098f2ff17
Autor:
Yue Zhou, Gregory A. Phelps, Mikayla M. Mangrum, Jemma McLeish, Elise K. Phillips, Jinchao Lou, Christelle F. Ancajas, Jeffrey M. Rybak, Peter M. Oelkers, Richard E. Lee, Michael D. Best, Todd B. Reynolds
Publikováno v:
mBio, Vol 15, Iss 5 (2024)
ABSTRACTSystemic infections by Candida spp. are associated with high mortality rates, partly due to limitations in current antifungals, highlighting the need for novel drugs and drug targets. The fungal phosphatidylserine synthase, Cho1, from Candida
Externí odkaz:
https://doaj.org/article/78c37e13beb64762ba0868b9367af010
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT To successfully induce disease, Candida albicans must effectively evade the host immune system. One mechanism used by C. albicans to achieve this is to mask immunogenic β(1,3)-glucan epitopes within its cell wall under an outer layer of man
Externí odkaz:
https://doaj.org/article/96f3ae7615d74663b8e957ac9dca9926
Autor:
Andrew S Wagner, Stephen W Lumsdaine, Mikayla M Mangrum, Ainsley E King, Trevor J Hancock, Timothy E Sparer, Todd B Reynolds
Publikováno v:
PLoS Genetics, Vol 18, Iss 9, p e1010405 (2022)
In order to successfully induce disease, the fungal pathogen Candida albicans regulates exposure of antigens like the cell wall polysaccharide ß(1,3)-glucan to the host immune system. C. albicans covers (masks) ß(1,3)-glucan with a layer of mannosy
Externí odkaz:
https://doaj.org/article/701a003d398e45fcb66bc35c03808cc2
Autor:
Andrew S Wagner, Trevor J Hancock, Stephen W Lumsdaine, Sarah J Kauffman, Mikayla M Mangrum, Elise K Phillips, Timothy E Sparer, Todd B Reynolds
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009839 (2021)
Masking the immunogenic cell wall epitope ß(1,3)-glucan under an outer layer of mannosylated glycoproteins is an important virulence factor deployed by Candida albicans during infection. Consequently, increased ß(1,3)-glucan exposure (unmasking) re
Externí odkaz:
https://doaj.org/article/cdfab09a60b748168be22f81e6fb3981
Autor:
Matthew J. Kerwin, Sula Mazimba, Kuldeep Shah, Younghoon Kwon, Jonathan Saado, James M Mangrum, David E. Haines, Nishaki Mehta, Michael Salerno
Publikováno v:
The American Journal of Cardiology. 164:57-63
The incidence of new-onset secondary atrial fibrillation (NOSAF) is as high as 44% in noncardiac critical illness. A systematic review and meta-analysis were performed to evaluate the impact of NOSAF, compared with history of prior atrial fibrillatio
Autor:
Kenneth C. Bilchick, Katerina Morgaenko, Chris A Campbell, J. M Mangrum, Brittney Heard, Pamela K. Mason, Nishaki Mehta, Edward Rojas-Pena, David E. Haines, Rohit Malhotra, Andrew E. Darby
Publikováno v:
Journal of Arrhythmia, Vol 37, Iss 2, Pp 400-406 (2021)
Journal of Arrhythmia
Journal of Arrhythmia
Aims Dermatologic evaluation for cardiac implantable electronic devices (CIEDs) has not been established. We sought to ascertain baseline wound scar features using quantifiable surgical tools and scar scales on post‐CIED patients. Methods A single
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Mikayla M. Mangrum, Trevor J. Hancock, Elise K. Phillips, Tim E. Sparer, Todd B. Reynolds, Stephen W. Lumsdaine, Sarah Kauffman, Andrew S. Wagner
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 8, p e1009839 (2021)
PLoS Pathogens, Vol 17, Iss 8, p e1009839 (2021)
Masking the immunogenic cell wall epitope ß(1,3)-glucan under an outer layer of mannosylated glycoproteins is an important virulence factor deployed by Candida albicans during infection. Consequently, increased ß(1,3)-glucan exposure (unmasking) re