Zobrazeno 1 - 10
of 61
pro vyhledávání: '"M. Maksimainen"'
Publikováno v:
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, Vol XLIV-4-W1-2020, Pp 159-165 (2020)
Visualization applications are an increasingly significant component in the field of 3D geo-information. In them, the utilization of consumer grade virtual reality (VR) head mounted displays (HMD) has become a topical research question. It is notable
Externí odkaz:
https://doaj.org/article/1b4c4cdb97c14c248f1b53849bd43ef1
Publikováno v:
ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, Vol V-1-2020, Pp 199-205 (2020)
The integration of the 3D measurement techniques with luminance imaging has increased the potential for mapping night-time road lighting conditions. In this study, we present selected static and mobile approaches for the purpose. The measurement meth
Externí odkaz:
https://doaj.org/article/98c8806b0371477e8848b82baed05ffd
Autor:
Dr. Patricia Korn, Arno Classen, Dr. Sudarshan Murthy, Dr. Riccardo Guareschi, Mirko M. Maksimainen, Barbara E. Lippok, Albert Galera‐Prat, Sven T. Sowa, Catharina Voigt, Prof. Dr. Giulia Rossetti, Prof. Dr. Lari Lehtiö, Prof. Dr. Carsten Bolm, Prof. Dr. Bernhard Lüscher
Publikováno v:
ChemistryOpen, Vol 10, Iss 10, Pp 939-948 (2021)
Abstract Intracellular ADP‐ribosyltransferases catalyze mono‐ and poly‐ADP‐ribosylation and affect a broad range of biological processes. The mono‐ADP‐ribosyltransferase PARP10 is involved in signaling and DNA repair. Previous studies ide
Externí odkaz:
https://doaj.org/article/0e125f0171b24e93b9aec1f09fcdc7ff
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Poly(ADP-ribose) polymerase 2 (PARP2) is activated by 5′-phosphorylated DNA breaks but the molecular mechanism is not fully understood. Here, the authors report a crystal structure of PARP2 bound to an activating DNA fragment, providing insights in
Externí odkaz:
https://doaj.org/article/3e12a12ec89744fea3a04b2b30548e8f
Autor:
Mirko M. Maksimainen, Antti Nurmesjärvi, Reima A. Terho, Michael D. Threadgill, Lari Lehtiö, Juha P. Heiskanen
Publikováno v:
ACS Omega, Vol 5, Iss 22, Pp 13447-13453 (2020)
Externí odkaz:
https://doaj.org/article/43bf483d33bf4b5f96712abac7d635da
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0223870 (2020)
Lactate oxidases belong to a group of FMN-dependent enzymes and they catalyze a conversion of lactate to pyruvate with a release of hydrogen peroxide. Hydrogen peroxide is also utilized as a read out in biosensors to quantitate lactate levels in biol
Externí odkaz:
https://doaj.org/article/d6bff684775d40468d3bd47bfcf7a10d
Publikováno v:
Journal of Medicinal Chemistry. 65:7532-7560
Major advances have recently defined functions for human mono-ADP-ribosylating PARP enzymes (mono-ARTs), also opening up potential applications for targeting them to treat diseases. Structural biology combined with medicinal chemistry has allowed the
Autor:
Sudarshan, Murthy, Maria Giulia, Nizi, Mirko M, Maksimainen, Serena, Massari, Juho, Alaviuhkola, Barbara E, Lippok, Chiara, Vagaggini, Sven T, Sowa, Albert, Galera-Prat, Yashwanth, Ashok, Harikanth, Venkannagari, Renata, Prunskaite-Hyyryläinen, Elena, Dreassi, Bernhard, Lüscher, Patricia, Korn, Oriana, Tabarrini, Lari, Lehtiö
Publikováno v:
Journal of medicinal chemistry.
We report [1,2,4]triazolo[3,4
Autor:
Sudarshan Murthy, Maria Giulia Nizi, Mirko M. Maksimainen, Serena Massari, Juho Alaviuhkola, Barbara E. Lippok, Chiara Vagaggini, Sven T. Sowa, Albert Galera-Prat, Yashwanth Ashok, Harikanth Venkannagari, Renata Prunskaite-Hyyryläinen, Elena Dreassi, Bernhard Lüscher, Patricia Korn, Oriana Tabarrini, Lari Lehtiö
Publikováno v:
Journal of medicinal chemistry 66(2), 1301-1320 (2023). doi:10.1021/acs.jmedchem.2c01460
Journal of medicinal chemistry 66(2), 1301-1320 (2023). doi:10.1021/acs.jmedchem.2c01460
Published by American Chemical Society, Washington, DC
Published by American Chemical Society, Washington, DC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02c78b88c3e04c15acc5405940609a1
http://urn.fi/urn:nbn:fi-fe2023032232837
http://urn.fi/urn:nbn:fi-fe2023032232837
Autor:
Patricia Korn, Lari Lehtiö, Bernhard Lüscher, Sven T. Sowa, Arno Classen, Giulia Rossetti, Barbara E. Lippok, Mirko M. Maksimainen, Carsten Bolm, Riccardo Guareschi, Albert Galera-Prat, Sudarshan Murthy, Catharina Voigt
Publikováno v:
ChemistryOpen
ChemistryOpen, Vol 10, Iss 10, Pp 939-948 (2021)
ChemistryOpen : including thesis treasury 10(10), 939-948 (2021). doi:10.1002/open.202100087
ChemistryOpen 10(10), 939-948 (2021). doi:10.1002/open.202100087
ChemistryOpen, Vol 10, Iss 10, Pp 939-948 (2021)
ChemistryOpen : including thesis treasury 10(10), 939-948 (2021). doi:10.1002/open.202100087
ChemistryOpen 10(10), 939-948 (2021). doi:10.1002/open.202100087
Intracellular ADP‐ribosyltransferases catalyze mono‐ and poly‐ADP‐ribosylation and affect a broad range of biological processes. The mono‐ADP‐ribosyltransferase PARP10 is involved in signaling and DNA repair. Previous studies identified O