Zobrazeno 1 - 10
of 1 045
pro vyhledávání: '"M. Mahler"'
Publikováno v:
Nuclear Materials and Energy, Vol 15, Iss , Pp 85-91 (2018)
For the design of future fusion reactors the ferritic-martensitic steel Eurofer97 is the main candidate for in-vessel structural application to be able to withstand harsh environment like irradiation and cyclic loading under elevated temperatures. In
Externí odkaz:
https://doaj.org/article/a38ec2adbb90454e86c8e63f9752fbf5
Publikováno v:
Nuclear Materials and Energy, Vol 9, Iss C, Pp 535-538 (2016)
The damage caused by creep-fatigue is an important factor for materials at high temperatures. For in-vessel components of fusion reactors the material EUROFER97 is a candidate for structural application where it is subjected to irradiation and cyclic
Externí odkaz:
https://doaj.org/article/465724927e524f0799a855ef403d0892
Autor:
M. Infantino, C. Bentow, A. Seaman, M. Benucci, F. Atzeni, P. Sarzi-Puttini, B. Olivito, F. Meacci, M. Manfredi, M. Mahler
Publikováno v:
Clinical and Developmental Immunology, Vol 2013 (2013)
Objective. We aimed to compare a chemiluminescent immunoassay (CIA, QUANTA Flash) on BIO-FLASH with a multiplex flow immunoassay (MFI) on BioPlex 2200 for the detection of antibodies to Ro60, Ro52, and SS-B. Methods. The study included 241 samples, f
Externí odkaz:
https://doaj.org/article/bf5ec4acb5dc4643a022d5f680d66d3f
Publikováno v:
Indonesian Journal of Pharmacy, Pp 96-105 (2021)
The traditional chemotherapy drug has been used as a standard cancer treatment, however it has resulted a modest survival benefit and damaged non-cancerous cells. Thus, the novel strategies which can improve selectivity and specificity in chemotherap
Externí odkaz:
https://doaj.org/article/02e0cdb3dc284c18b07c1cbd8758cd07
Autor:
Lucia F. Zacchi, Dinora Roche-Recinos, Cassandra L. Pegg, Toan K. Phung, Mark Napoli, Campbell Aitken, Vanessa Sandford, Stephen M. Mahler, Yih Yean Lee, Benjamin L. Schulz, Christopher B. Howard
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-19 (2021)
Zacchi et al. attempt to bridge the gap between understanding the impact of process variables and determination of critical post-translational modifications on a highly complex glycoprotein, factor IX. They implement an LC-MS/MS approach based on dat
Externí odkaz:
https://doaj.org/article/71aba8fb8f8b4392a1a05cbdb5d2e86f
Autor:
Maria E. Lund, Christopher B. Howard, Kristofer J. Thurecht, Douglas H. Campbell, Stephen M. Mahler, Bradley J. Walsh
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Glypican-1 is a heparan sulfate proteoglycan that is overexpressed in prostate cancer (PCa), and a variety of solid tumors. Importantly, expression is restricted in normal tissue, making it an ideal tumor targeting antigen. Since
Externí odkaz:
https://doaj.org/article/1668823008e34a798cd55eef76770f0d
Autor:
Zachary H. Houston, Jens Bunt, Kok-Siong Chen, Simon Puttick, Christopher B. Howard, Nicholas L. Fletcher, Adrian V. Fuchs, Jiwei Cui, Yi Ju, Gary Cowin, Xin Song, Andrew W. Boyd, Stephen M. Mahler, Linda J. Richards, Frank Caruso, Kristofer J. Thurecht
Publikováno v:
ACS Central Science, Vol 6, Iss 5, Pp 727-738 (2020)
Externí odkaz:
https://doaj.org/article/3fb1a902064e45d0828820d915363b4e
Autor:
Michelle L. M. Mulder, Johanna E. Vriezekolk, Nathan den Broeder, Elien A. M. Mahler, Philip S. Helliwell, Frank H. J. van den Hoogen, Alfons A. den Broeder, Mark H. Wenink
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background Both methotrexate (MTX) and leflunomide (LEF) are registered and regularly prescribed as first-line treatments for the use in patients with psoriatic arthritis (PsA) and they are occasionally used in combination. However, evidence
Externí odkaz:
https://doaj.org/article/0366f0dcebf94900ab492015d476f512
Autor:
Celia A. J. Michielsens, Nadine Boers, Nathan den Broeder, Mark H. Wenink, Aatke van der Maas, Elien A. M. Mahler, Michelle L. M. Mulder, Désirée van der Heijde, Frank H. J. van den Hoogen, Lise M. Verhoef, Alfons A. den Broeder
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background Tumour necrosis factor inhibitors (TNFi) are effective in the treatment of patients with spondyloarthritis (SpA), including psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA). However, these drugs come with some disadva
Externí odkaz:
https://doaj.org/article/57219f3f31494167bd5e7678b9c9b2fc
Autor:
Mohamed A. Alfaleh, Hashem O. Alsaab, Ahmad Bakur Mahmoud, Almohanad A. Alkayyal, Martina L. Jones, Stephen M. Mahler, Anwar M. Hashem
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Monoclonal antibodies (mAbs) have become one of the most important classes of biopharmaceutical products, and they continue to dominate the universe of biopharmaceutical markets in terms of approval and sales. They are the most profitable single prod
Externí odkaz:
https://doaj.org/article/eb81d7b6c16242adb96c2b5f6566c87e