Zobrazeno 1 - 10
of 81
pro vyhledávání: '"M. Madl"'
Autor:
Matteo Togninalli, Andrew T. V. Ho, Christopher M. Madl, Colin A. Holbrook, Yu Xin Wang, Klas E. G. Magnusson, Anna Kirillova, Andrew Chang, Helen M. Blau
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract The proper regulation of muscle stem cell (MuSC) fate by cues from the niche is essential for regeneration of skeletal muscle. How pro-regenerative niche factors control the dynamics of MuSC fate decisions remains unknown due to limitations
Externí odkaz:
https://doaj.org/article/06237dbc4b9c438c85677ca7e4a9b4bb
Autor:
Christopher M. Madl
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106825- (2023)
Summary: Aging is characterized by progressive decline in tissue function and represents the greatest risk factor for many diseases. Nevertheless, many fundamental mechanisms driving human aging remain poorly understood. Aging studies using model org
Externí odkaz:
https://doaj.org/article/811b757486cf408d9c57cbac1012cc39
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 69 (2024)
Aging is a complex multifactorial process that results in tissue function impairment across the whole organism. One of the common consequences of this process is the loss of muscle mass and the associated decline in muscle function, known as sarcopen
Externí odkaz:
https://doaj.org/article/ebb4bedf781848d5b1f7c4cfcd2eebf1
Publikováno v:
Journal of Behavioral Medicine. 45:841-854
MRI-related anxiety is present in 30% of patients and may evoke motion artifacts/failed scans, which impair clinical efficiency. It is unclear how patient anxiety can be countered most effectively. Habitual preferences for coping with stressful situa
Autor:
Christopher M Madl, Sarah C Heilshorn
Publikováno v:
Neural Regeneration Research, Vol 10, Iss 4, Pp 514-517 (2015)
Both matrix biochemistry and neurotrophic factors are known to modulate neurite outgrowth and pathfinding however, the interplay between these two factors is less studied. While previous work has shown that the biochemical identity of the matrix can
Externí odkaz:
https://doaj.org/article/8603c58a188f434e9096cea3007cf8d8
Autor:
Matteo Togninalli, Andrew T.V. Ho, Christopher M. Madl, Colin A. Holbrook, Yu Xin Wang, Klas E.G. Magnusson, Anna Kirillova, Andrew Chang, Helen M. Blau
The proper regulation of muscle stem cell (MuSC) fate by cues from the niche is essential for regeneration of skeletal muscle. How pro-regenerative niche factors control the dynamics of MuSC fate decisions remains unknown due to limitations of popula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0de7f78e51e9b7859056dd17cb03ae87
https://doi.org/10.1101/2022.06.17.495556
https://doi.org/10.1101/2022.06.17.495556
Publikováno v:
ACS Macro Lett
Recent efforts to develop hydrogel biomaterials have focused on better recapitulating the dynamic properties of the native extracellular matrix. In hydrogel biomaterials, binding thermodynamics and cross-link kinetics directly affect numerous bulk dy
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Publikováno v:
Biomaterials
Skeletal muscle stem cells (MuSCs) are essential for efficacious muscle repair, making MuSCs promising therapeutic targets for tissue engineering and regenerative medicine. MuSCs are presented with a diverse and temporally defined set of cues from th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7785ddd4a2b490e1b5c513282c98522
https://europepmc.org/articles/PMC8325634/
https://europepmc.org/articles/PMC8325634/
Publikováno v:
Chem Mater
Recent efforts in the design of hydrogel biomaterials have focused on better mimicking the native cellular microenvironment to direct cell fate. To simultaneously control multiple material parameters, several orthogonal chemistries may be needed. How