Zobrazeno 1 - 10
of 703
pro vyhledávání: '"M. MORTIMER"'
Autor:
Jack S. Gisby, Norzawani B. Buang, Artemis Papadaki, Candice L. Clarke, Talat H. Malik, Nicholas Medjeral-Thomas, Damiola Pinheiro, Paige M. Mortimer, Shanice Lewis, Eleanor Sandhu, Stephen P. McAdoo, Maria F. Prendecki, Michelle Willicombe, Matthew C. Pickering, Marina Botto, David C. Thomas, James E. Peters
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
End-stage kidney disease confers a high risk for severe COVID-19 infection. Using an at-risk group (end-stage kidney disease patients with COVID-19), authors using RNA-sequencing of immune cells and plasma proteomic profiling to investigate the host
Externí odkaz:
https://doaj.org/article/6195c991b86743c2bc2cea16ffcb650a
Autor:
Michael J. Doane, Leona Bessonova, Haley S. Friedler, Kathleen M. Mortimer, Harry Cheng, Thomas Brecht, Amy K. O’Sullivan, Hannah Cummings, David McDonnell, Jonathan M. Meyer
Publikováno v:
BMC Psychiatry, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Many second-generation antipsychotics (SGAs) are associated with weight gain and cardiometabolic effects. Antipsychotic-associated weight gain is linked to treatment interruptions, potentially increasing risk of relapse and hospit
Externí odkaz:
https://doaj.org/article/2eccad05e5a7416594f176979e2a24dc
Autor:
Lyra O Randzavola, Paige M Mortimer, Emma Garside, Elizabeth R Dufficy, Andrea Schejtman, Georgia Roumelioti, Lu Yu, Mercedes Pardo, Kerstin Spirohn, Charlotte Tolley, Cordelia Brandt, Katherine Harcourt, Esme Nichols, Mike Nahorski, Geoff Woods, James C Williamson, Shreehari Suresh, John M Sowerby, Misaki Matsumoto, Celio XC Santos, Cher Shen Kiar, Subhankar Mukhopadhyay, William M Rae, Gordon J Dougan, John Grainger, Paul J Lehner, Michael A Calderwood, Jyoti Choudhary, Simon Clare, Anneliese Speak, Giorgia Santilli, Alex Bateman, Kenneth GC Smith, Francesca Magnani, David C Thomas
Publikováno v:
eLife, Vol 11 (2022)
EROS (essential for reactive oxygen species) protein is indispensable for expression of gp91phox, the catalytic core of the phagocyte NADPH oxidase. EROS deficiency in humans is a novel cause of the severe immunodeficiency, chronic granulomatous dise
Externí odkaz:
https://doaj.org/article/1b48b81ab31e44d4a2884318ac761009
Publikováno v:
F&S Reports, Vol 3, Iss 3, Pp 178- (2022)
Externí odkaz:
https://doaj.org/article/531d9c650c6040a7b43453c65520e3db
Autor:
Govindarajan Narayanan, Malcolm M. Bilimoria, Peter J. Hosein, Zhaohui Su, Kathleen M. Mortimer, Robert C. G. Martin
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Irreversible electroporation (IRE) is a local ablation technique utilizing high voltage, low energy direct current to create nanopores in cell membrane which disrupt homeostasis and leads to cell death. Previous reports have sugge
Externí odkaz:
https://doaj.org/article/517df446e4354201898909c2250a52b5
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Reactive oxygen species (ROS) derived from the phagocyte NADPH oxidase (NOX2) are essential for host defence and immunoregulation. Their levels must be tightly controlled. ROS are required to prevent infection and are used in signalling to regulate s
Externí odkaz:
https://doaj.org/article/4f32564fc2aa4ec89f6e404ed1516810
Autor:
Jack Gisby, Candice L Clarke, Nicholas Medjeral-Thomas, Talat H Malik, Artemis Papadaki, Paige M Mortimer, Norzawani B Buang, Shanice Lewis, Marie Pereira, Frederic Toulza, Ester Fagnano, Marie-Anne Mawhin, Emma E Dutton, Lunnathaya Tapeng, Arianne C Richard, Paul DW Kirk, Jacques Behmoaras, Eleanor Sandhu, Stephen P McAdoo, Maria F Prendecki, Matthew C Pickering, Marina Botto, Michelle Willicombe, David C Thomas, James E Peters
Publikováno v:
eLife, Vol 10 (2021)
End-stage kidney disease (ESKD) patients are at high risk of severe COVID-19. We measured 436 circulating proteins in serial blood samples from hospitalised and non-hospitalised ESKD patients with COVID-19 (n = 256 samples from 55 patients). Comparis
Externí odkaz:
https://doaj.org/article/bbf513cf4b974a538355b6474ff58476
Autor:
Sierra M Mortimer, Trenton J Frisbie, John B Moldovan, Mitsuhiro Nakamura, Siara N Sandwith, John Yin, John V Moran
Publikováno v:
eLS. :1-18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8055d16f6388c01e0fc44e69980296ad
https://doi.org/10.1002/9780470015902.a0025409
https://doi.org/10.1002/9780470015902.a0025409
Publikováno v:
Neurointervention, Vol 12, Iss 2, Pp 59-68 (2017)
PurposeThe safety and efficacy of endovascular thrombectomy (EVT) for patients with proximal occlusive stroke presenting beyond 6 hours and selected on the basis of favorable neuroimaging remains unclear.Materials and MethodsA systematic search was p
Externí odkaz:
https://doaj.org/article/340f1c18ae454cf2ab52caef37bd539d
Autor:
Paige M Mortimer, Esme Nichols, Joe Thomas, Rachna Shanbhag, Neha Singh, Eve L Coomber, Talat H Malik, Matthew C Pickering, Lyra Randzavola, William Rae, Sagar Bhattad, David C Thomas
Chronic Granulomatous Disease (CGD) is an inborn error of immunity characterised by opportunistic infection and sterile granulomatous inflammation. CGD is caused by a failure of reactive oxygen species (ROS) production by the phagocyte NADPH oxidase.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bccbd2955c8c2759bcba10e3c6c2f683
https://doi.org/10.1101/2023.04.21.23286144
https://doi.org/10.1101/2023.04.21.23286144
