Zobrazeno 1 - 10
of 182
pro vyhledávání: '"M. M. van den Heuvel"'
Autor:
A. M. van Hulst, E. J. Verwaaijen, M. F. Fiocco, S. M. F. Pluijm, M. A. Grootenhuis, R. Pieters, E. L. T. van den Akker, M. M. van den Heuvel-Eibrink
Publikováno v:
BMC Pediatrics, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Dexamethasone, a highly effective drug in treating pediatric acute lymphoblastic leukemia (ALL), can induce serious neurobehavioral side effects. These side effects are experienced by patients and parents as detrimental with respe
Externí odkaz:
https://doaj.org/article/08ba3da1d9554c76bbc077b8c7062f17
Autor:
A. J. M. Meijer, F. A. Diepstraten, T. Langer, L. Broer, I. K. Domingo, E. Clemens, A. G. Uitterlinden, A. C. H. de Vries, M. van Grotel, W. P. Vermeij, R. A. Ozinga, H. Binder, J. Byrne, E. van Dulmen-den Broeder, M. L. Garrè, D. Grabow, P. Kaatsch, M. Kaiser, L. Kenborg, J. F. Winther, C. Rechnitzer, H. Hasle, T. Kepak, K. Kepakova, W. J. E. Tissing, A. L. F. van der Kooi, L. C. M. Kremer, J. Kruseova, S. M. F. Pluijm, C. E. Kuehni, H. J. H. van der Pal, R. Parfitt, C. Spix, A. Tillmanns, D. Deuster, P. Matulat, G. Calaminus, A. E. Hoetink, S. Elsner, J. Gebauer, R. Haupt, H. Lackner, C. Blattmann, S. J. C. M. M. Neggers, S. R. Rassekh, G. E. B. Wright, B. Brooks, A. P. Nagtegaal, B. I. Drögemöller, C. J. D. Ross, A. P. Bhavsar, A. G. am Zehnhoff-Dinnesen, B. C. Carleton, O. Zolk, M. M. van den Heuvel-Eibrink, the PanCareLIFE Consortium, and the CPNDS Consortium
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)
Abstract In children with cancer, the heterogeneity in ototoxicity occurrence after similar treatment suggests a role for genetic susceptibility. Using a genome-wide association study (GWAS) approach, we identified a genetic variant in TCERG1L (rs893
Externí odkaz:
https://doaj.org/article/1a21ee1f4f0440f184693f4b2b482abf
Autor:
N. Oosterom, M. Fiocco, R. Q. H. Kloos, I. M. van der Sluis, R. Pieters, B. D. van Zelst, D. E. C. Smith, M. M. van den Heuvel-Eibrink, R. de Jonge, S. G. Heil
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background After High-Dose Methotrexate (HD-MTX), folinic acid rescue therapy (Leucovorin) is administered to reduce side effects in pediatric acute lymphoblastic leukemia (ALL) patients. Leucovorin and MTX are structural analogues, possibly
Externí odkaz:
https://doaj.org/article/adb1e98d32e34de4a97a5e539ca4d3ec
Autor:
W. S. M. E. Theelen, O. Krijgsman, K. Monkhorst, T. Kuilman, D. D. G. C. Peters, S. Cornelissen, M. A. Ligtenberg, S. M. Willems, J. L. G. Blaauwgeers, C. J. M. van Noesel, D. S. Peeper, M. M. van den Heuvel, K. Schulze
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Background The tumor immune microenvironment is a heterogeneous entity. Gene expression analysis allows us to perform comprehensive immunoprofiling and may assist in dissecting the different components of the immune infiltrate. As gene expre
Externí odkaz:
https://doaj.org/article/debbea0e0b5047e685a2c5ef50af7bd0
Autor:
I M A A van Roessel, J E Gorter, B Bakker, M M van den Heuvel-Eibrink, M H Lequin, J van der Lugt, L Meijer, A Y N Schouten-van Meeteren, H M van Santen
Publikováno v:
Endocrine Connections, Vol 13, Iss 10, Pp 1-9 (2024)
Objective: Children with a supratentorial midline low-grade glioma (LGG) may be at risk for impaired bone health due to hypothalamic-pituitary dysfunction, obesity, exposure to multiple treatment modalities, and/or decreased mobility. The presence of
Externí odkaz:
https://doaj.org/article/7ed742e2aa934db7a99ef62ed41a9caf
Autor:
R D Schouten, I Schouten, M M F Schuurbiers, V van der Noort, R A M Damhuis, E H F M van der Heijden, J A Burgers, N P Barlo, A S R van Lindert, K W Maas, J J G van den Brand, A A J Smit, J M W van Haarst, B van der Maat, E Schuuring, H Blaauwgeers, S M Willems, K Monkhorst, D van den Broek, M M van den Heuvel
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0290939 (2024)
IntroductionMolecular profiling of NSCLC is essential for optimising treatment decisions, but often incomplete. We assessed the efficacy of protocolised molecular profiling in the current standard-of-care (SoC) in a prospective observational study in
Externí odkaz:
https://doaj.org/article/87e38726aa1c4be1b473231f9e459023
Publikováno v:
13.02 - Pulmonary embolism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efc2a7acbb099770cd854a847ff8c539
https://doi.org/10.1183/13993003.congress-2022.953
https://doi.org/10.1183/13993003.congress-2022.953
Publikováno v:
01.05 - Clinical respiratory physiology, exercise and functional imaging.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1445b62123868e5a8e5ff19db5535c59
https://doi.org/10.1183/13993003.congress-2022.945
https://doi.org/10.1183/13993003.congress-2022.945
Autor:
Alison Leiper, L. C. M. Kremer, Jeanette Falck Winther, James M. Byrne, Dalit Modan-Moses, M M van den Heuvel-Eibrink, Riccardo Haupt, C.B. Lambalk, Melanie Kaiser, J.W.R. Twisk, M. van den Berg, Claudia Spix, Uta Dirksen, Claire Berger, Tomáš Kepák, Jarmila Kruseova, M. van Dijk, Cécile M. Ronckers, E. van Dulmen-den Broeder, Peter Kaatsch, F.E. van Leeuwen, Desiree Grabow, A.L.F. van der Kooi, Victoria Grandage, Sophie D. Fosså
Publikováno v:
PanCareLIFE Consortium 2021, ' Treatment-related fertility impairment in long-term female childhood, adolescent and young adult cancer survivors : investigating dose-effect relationships in a European case-control study (PanCareLIFE) ', Human reproduction (Oxford, England), vol. 36, no. 6, pp. 1561-1573 . https://doi.org/10.1093/humrep/deab035
Human reproduction (Oxford, England), 36(6), 1561-1573. Oxford University Press
van den Berg, M H, van Dijk, M, Byrne, J, Berger, C, Dirksen, U, Winther, J F, Fossa, S D, Grabow, D, Grandage, V L, Haupt, R, van den Heuvel-Eibrink, M M, Kaiser, M, Kepak, T, van der Kooi, A L F, Kremer, L C M, Kruseova, J, Lambalk, C B, van Leeuwen, F E, Leiper, A, Modan-Moses, D, Spix, C, Twisk, J W R, Ronckers, C M, Kaatsch, P, van Dulmen-den Broeder, E & PanCareLIFE Consortium 2021, ' Treatment-related fertility impairment in long-term female childhood, adolescent and young adult cancer survivors : investigating dose-effect relationships in a European case-control study (PanCareLIFE) ', Human Reproduction, vol. 36, no. 6, pp. 1561-1573 . https://doi.org/10.1093/humrep/deab035
Human reproduction (Oxford, England), 36(6), 1561-1573. Oxford University Press
van den Berg, M H, van Dijk, M, Byrne, J, Berger, C, Dirksen, U, Winther, J F, Fossa, S D, Grabow, D, Grandage, V L, Haupt, R, van den Heuvel-Eibrink, M M, Kaiser, M, Kepak, T, van der Kooi, A L F, Kremer, L C M, Kruseova, J, Lambalk, C B, van Leeuwen, F E, Leiper, A, Modan-Moses, D, Spix, C, Twisk, J W R, Ronckers, C M, Kaatsch, P, van Dulmen-den Broeder, E & PanCareLIFE Consortium 2021, ' Treatment-related fertility impairment in long-term female childhood, adolescent and young adult cancer survivors : investigating dose-effect relationships in a European case-control study (PanCareLIFE) ', Human Reproduction, vol. 36, no. 6, pp. 1561-1573 . https://doi.org/10.1093/humrep/deab035
STUDY QUESTION Which chemotherapeutic agents and body site-specific radiation fields are dose-dependently associated with an increased risk of fertility impairment in long-term female childhood, adolescent and young adulthood (CAYA) cancer survivors?
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d41e6100776ef7922e69c991967087
https://pure.eur.nl/en/publications/413cab3b-347e-42bc-9dfb-feee89874cec
https://pure.eur.nl/en/publications/413cab3b-347e-42bc-9dfb-feee89874cec
Autor:
Wim J. E. Tissing, J Kruseova, A E Hoetink, G Calaminus, R Haupt, I K Domingo, E van Dulmen-den Broeder, Amit P. Bhavsar, J Byrne, H Hasle, C Spix, S Elsner, A P Nagtegaal, L Kenborg, J Gebauer, O Zolk, S M F Pluijm, A J M Meijer, H Binder, R A Ozinga, C Rechnitzer, S J C M M Neggers, M L Garrè, P Matulat, D Deuster, T Langer, Britt I. Drögemöller, H. J. H. van der Pal, D Grabow, Leontien C. M. Kremer, Galen E.B. Wright, E Clemens, A.L.F. van der Kooi, M Kaiser, Bruce Carleton, F A Diepstraten, J F Winther, C Blattmann, L Broer, M van Grotel, R Parfitt, A G Am Zehnhoff-Dinnesen, K Kepakova, H Lackner, M M van den Heuvel-Eibrink, Shahrad Rod Rassekh, T Kepak, A. C. H. de Vries, Beth Brooks, André G. Uitterlinden, C. E. Kuehni, A Tillmanns, Wilbert P. Vermeij, Colin J. D. Ross, P Kaatsch
Publikováno v:
37. Wissenschaftliche Jahrestagung der Deutschen Gesellschaft für Phoniatrie und Pädaudiologie (DGPP); 20210917-20210918; sine loco [digital]; DOCP15 /20211028/
The PanCareLIFE Consortium & and the CPNDS Consortium 2021, ' TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE study ', npj Precision Oncology, vol. 5, no. 1, 64 . https://doi.org/10.1038/s41698-021-00178-z
Meijer, A J M, Diepstraten, F A, Langer, T, Broer, L, Domingo, I K, Clemens, E, Uitterlinden, A G, de Vries, A C H, van Grotel, M, Vermeij, W P, Ozinga, R A, Binder, H, Byrne, J, van Dulmen-den Broeder, E, Garrè, M L, Grabow, D, Kaatsch, P, Kaiser, M, Kenborg, L, Winther, J F, Rechnitzer, C, Hasle, H, Kepak, T, Kepakova, K, Tissing, W J E, van der Kooi, A L F, Kremer, L C M, Kruseova, J, Pluijm, S M F, Kuehni, C E, van der Pal, H J H, Parfitt, R, Spix, C, Tillmanns, A, Deuster, D, Matulat, P, Calaminus, G, Hoetink, A E, Elsner, S, Gebauer, J, Haupt, R, Lackner, H, Blattmann, C, Neggers, S J C M M, Rassekh, S R, Wright, G E B, Brooks, B, Nagtegaal, A P, Drögemöller, B I, Ross, C J D, The PanCareLIFE consortium & and the CPNDS Consortium 2021, ' TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE study ', npj Precision Oncology, vol. 5, no. 1, 64 . https://doi.org/10.1038/s41698-021-00178-z
Meijer, A J M, Diepstraten, F A, Langer, T, Broer, L, Domingo, I K, Clemens, E, Uitterlinden, A G, de Vries, A C H, van Grotel, M, Vermeij, W P, Ozinga, R A, Binder, H, Byrne, J, van Dulmen-den Broeder, E, Garrè, M L, Grabow, D, Kaatsch, P, Kaiser, M, Kenborg, L, Winther, J F, Rechnitzer, C, Hasle, H, Kepak, T, Kepakova, K, Tissing, W J E, van der Kooi, A L F, Kremer, L C M, Kruseova, J, Pluijm, S M F, Kuehni, C E, van der Pal, H J H, Parfitt, R, Spix, C, Tillmanns, A, Deuster, D, Matulat, P, Calaminus, G, Hoetink, A E, Elsner, S, Gebauer, J, Haupt, R, Lackner, H, Blattmann, C, Neggers, S J C M M, Rassekh, S R, Wright, G E B, Brooks, B, Nagtegaal, A P, Drögemöller, B I, Ross, C J D, the PanCareLIFE Consortium & and the CPNDS Consortium 2021, ' TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE study ', npj Precision Oncology, vol. 5, 64 . https://doi.org/10.1038/s41698-021-00178-z
npj Precision Oncology, 5(1):64. Springer Nature
Meijer, A J M; Diepstraten, F A; Langer, T; Broer, L; Domingo, I K; Clemens, E; Uitterlinden, A G; de Vries, A C H; van Grotel, M; Vermeij, W P; Ozinga, R A; Binder, H; Byrne, J; van Dulmen-den Broeder, E; Garrè, M L; Grabow, D; Kaatsch, P; Kaiser, M; Kenborg, L; Winther, J F; ... (2021). TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE study. NPJ precision oncology, 5(1), p. 64. Springer Nature 10.1038/s41698-021-00178-z
NPJ Precision Oncology
NPJ precision oncology, 5(1):64, 1-8. Nature Research
npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)
The PanCareLIFE Consortium & and the CPNDS Consortium 2021, ' TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE study ', npj Precision Oncology, vol. 5, no. 1, 64 . https://doi.org/10.1038/s41698-021-00178-z
Meijer, A J M, Diepstraten, F A, Langer, T, Broer, L, Domingo, I K, Clemens, E, Uitterlinden, A G, de Vries, A C H, van Grotel, M, Vermeij, W P, Ozinga, R A, Binder, H, Byrne, J, van Dulmen-den Broeder, E, Garrè, M L, Grabow, D, Kaatsch, P, Kaiser, M, Kenborg, L, Winther, J F, Rechnitzer, C, Hasle, H, Kepak, T, Kepakova, K, Tissing, W J E, van der Kooi, A L F, Kremer, L C M, Kruseova, J, Pluijm, S M F, Kuehni, C E, van der Pal, H J H, Parfitt, R, Spix, C, Tillmanns, A, Deuster, D, Matulat, P, Calaminus, G, Hoetink, A E, Elsner, S, Gebauer, J, Haupt, R, Lackner, H, Blattmann, C, Neggers, S J C M M, Rassekh, S R, Wright, G E B, Brooks, B, Nagtegaal, A P, Drögemöller, B I, Ross, C J D, The PanCareLIFE consortium & and the CPNDS Consortium 2021, ' TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE study ', npj Precision Oncology, vol. 5, no. 1, 64 . https://doi.org/10.1038/s41698-021-00178-z
Meijer, A J M, Diepstraten, F A, Langer, T, Broer, L, Domingo, I K, Clemens, E, Uitterlinden, A G, de Vries, A C H, van Grotel, M, Vermeij, W P, Ozinga, R A, Binder, H, Byrne, J, van Dulmen-den Broeder, E, Garrè, M L, Grabow, D, Kaatsch, P, Kaiser, M, Kenborg, L, Winther, J F, Rechnitzer, C, Hasle, H, Kepak, T, Kepakova, K, Tissing, W J E, van der Kooi, A L F, Kremer, L C M, Kruseova, J, Pluijm, S M F, Kuehni, C E, van der Pal, H J H, Parfitt, R, Spix, C, Tillmanns, A, Deuster, D, Matulat, P, Calaminus, G, Hoetink, A E, Elsner, S, Gebauer, J, Haupt, R, Lackner, H, Blattmann, C, Neggers, S J C M M, Rassekh, S R, Wright, G E B, Brooks, B, Nagtegaal, A P, Drögemöller, B I, Ross, C J D, the PanCareLIFE Consortium & and the CPNDS Consortium 2021, ' TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE study ', npj Precision Oncology, vol. 5, 64 . https://doi.org/10.1038/s41698-021-00178-z
npj Precision Oncology, 5(1):64. Springer Nature
Meijer, A J M; Diepstraten, F A; Langer, T; Broer, L; Domingo, I K; Clemens, E; Uitterlinden, A G; de Vries, A C H; van Grotel, M; Vermeij, W P; Ozinga, R A; Binder, H; Byrne, J; van Dulmen-den Broeder, E; Garrè, M L; Grabow, D; Kaatsch, P; Kaiser, M; Kenborg, L; Winther, J F; ... (2021). TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE study. NPJ precision oncology, 5(1), p. 64. Springer Nature 10.1038/s41698-021-00178-z
NPJ Precision Oncology
NPJ precision oncology, 5(1):64, 1-8. Nature Research
npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)
Background: Ototoxicity (hearing loss, tinnitus and/or vertigo) is a serious adverse event of cisplatin treatment in children with cancer. The heterogeneity in ototoxicity occurrence after similar treatment suggests a role for genetic susceptibility.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b1abb74a67b5c6ca531ead07151865
http://www.egms.de/en/meetings/dgpp2021/21dgpp30.shtml
http://www.egms.de/en/meetings/dgpp2021/21dgpp30.shtml
