Výsledky vyhledávání - "M. M. Vigdorchik"

Indole derivatives. 131. The basicity of 5- and 6-aminoindoles

Autor: N. N. Suvorov, L. N. Kurkovskaya, I. V. Persianova, L. S. Krasavina, M. M. Vigdorchik, M. A. Salekh

Publikováno v: Chemistry of Heterocyclic Compounds. 24:624-627

The pKa values for the 5- and 6-aminoindoles were determined from potentiometric titration curves and from 13C NMR data on the total change of the chemical shifts of the carbon atom signals on protonation of the amino group. The pKa values obtained (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3eb6e42f773799f57cf4b798faf85b70
https://doi.org/10.1007/bf00475595

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Synthesis and pharmacological activity of 5,6-and 4,5-ethylenedioxytryptamines

Autor: M. M. Vigdorchik, L. N. Kuleshova, D. A. Partsvaniya, M. D. Mashkovskii, N. N. Suvorov, T. K. Trubitsyna, R. N. Akhvlediani, E. N. Gordeev

Publikováno v: Pharmaceutical Chemistry Journal. 20:833-838

It should be noted that with the Japp--Klingemann reaction hydrazone II is obtained in the syn form, which was confirmed by PMR data in CDCI~ (chemical shift of 7 NH is 12.73 ppm). The syn form of hydrazone II is easily converted to the anti form by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8341ab6cf94b46a882a23a5a1a1dde3e
https://doi.org/10.1007/bf00763713

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Indole derivatives. 125. Synthesis of disubstitutep tryptamines

Autor: G. N. Il'ina, K. F. Turchin, T. Ya. Filipenko, M. M. Vigdorchik, L. Kh. Vinograd, N. N. Suvorov

Publikováno v: Chemistry of Heterocyclic Compounds. 20:890-897

Disubstituted tryptamines, containing methyl, methoxy, nitro, and amino groups, chlorine, and bromine in the benzene ring, were synthesized. The influence of substituents on the course of individual stages of synthesis was noted.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b478c9cfa908da62462a172b19b1c475
https://doi.org/10.1007/bf00513577

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[Identification of N,N-dimethyl-O-(beta-D-glucopyranuronosyl)-5- hydroxytryptamine as a bufotenine metabolite in the rabbit]

Autor: M M, Vigdorchik, K F, Turchin, T A, Gus'kova, L M, Iakubovich, L S, Krasavina

Publikováno v: Bioorganicheskaia khimiia. 10(2)

A bufotenine metabolite has been isolated from the rabbit urine by the column chromatography on cellulose and preparative paper electrophoresis in acidic buffer. It has the structure of N,N-dimethyl-O-(beta-D-glucopyranuronosyl)-5-hydroxytryptamine a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::507fb99a7071a97dbf8696c2cfefe143
https://pubmed.ncbi.nlm.nih.gov/6091679

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