Výsledky vyhledávání - "M. M. Rechler"

Characterization of the inhibition of DNA synthesis in proliferating mink lung epithelial cells by insulin-like growth factor binding protein-3

Autor: H B, Wu, A, Kumar, W C, Tsai, D, Mascarenhas, J, Healey, M M, Rechler

Publikováno v: Journal of cellular biochemistry. 77(2)

Insulin-like growth factor binding protein-3 (IGFBP-3) can inhibit cell growth by directly interacting with cells, as well as by forming complexes with IGF-I and IGF-II that prevent their growth-promoting activity. The present study examines the mech

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e0433e198bac2c56b4f85262e04f3597
https://pubmed.ncbi.nlm.nih.gov/10723094

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Insulin inhibits the activation of transcription by a C-terminal fragment of the forkhead transcription factor FKHR. A mechanism for insulin inhibition of insulin-like growth factor-binding protein-1 transcription

Autor: M, Tomizawa, A, Kumar, V, Perrot, J, Nakae, D, Accili, M M, Rechler, A, Kumaro

Publikováno v: The Journal of biological chemistry. 275(10)

The forkhead rhabdomyosarcoma transcription factor (FKHR) is a promising candidate to be the transcription factor that binds to the insulin response element of the insulin-like growth factor-binding protein-1 (IGFBP-1) promoter and mediates insulin i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3c22eab1392909f5827adf37f5170dbd
https://pubmed.ncbi.nlm.nih.gov/10702299

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Growth inhibition by insulin-like growth factor (IGF) binding protein-3--what's IGF got to do with it?

Autor: M M, Rechler

Publikováno v: Endocrinology. 138(7)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::54e141804093419aa0d24cc9c649d36c
https://pubmed.ncbi.nlm.nih.gov/9202199

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Insulin-like growth factor-I and insulin stimulate the synthesis of IGF-binding protein-2 in a human embryonic kidney cell line

Autor: Y R, Boisclair, Y W, Yang, J M, Stewart, M M, Rechler

Publikováno v: Growth regulation. 4(3)

Insulin and insulin-like growth factor (IGF)-I are thought to be major metabolic regulators of IGF-binding protein-2 (IGFBP-2). We have examined the regulation of IGFBP-2 expression by IGF-I and insulin in 293 cells, a cell line derived from human em

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8c5efb9ba7acba7810a6dff545834ea3
https://pubmed.ncbi.nlm.nih.gov/7532054

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Three clustered Sp1 sites are required for efficient transcription of the TATA-less promoter of the gene for insulin-like growth factor-binding protein-2 from the rat

Autor: Y R, Boisclair, A L, Brown, S, Casola, M M, Rechler

Publikováno v: The Journal of biological chemistry. 268(33)

Insulin-like growth factor-binding protein-2 (IGF-BP-2) transcription in rat liver varies with developmental age and fasting. To define the DNA elements required for efficient expression of the TATA-less rat IGFBP-2 gene, the native or mutated promot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::008ce8f18bad4852a5181db2c4cd546f
https://pubmed.ncbi.nlm.nih.gov/7693708

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Cycloheximide stabilizes insulin-like growth factor-binding protein-1 (IGFBP-1) mRNA and inhibits IGFBP-1 transcription in H4-II-E rat hepatoma cells

Autor: G T, Ooi, D R, Brown, D S, Suh, L Y, Tseng, M M, Rechler

Publikováno v: The Journal of biological chemistry. 268(22)

The insulin-like growth factor-binding proteins (IGFBPs) are a family of six proteins that modulate the biological activity of IGF-I and IGF-II and determine their bioavailability to tissues. One of the IGFBPs, IGFBP-1, is distinctive in the dynamic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::12a2edd79c513b4a0b97cbda275e92eb
https://pubmed.ncbi.nlm.nih.gov/7688368

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Binding of mutants of human insulin-like growth factor II to insulin-like growth factor binding proteins 1-6

Autor: L A, Bach, S, Hsieh, K, Sakano, H, Fujiwara, J F, Perdue, M M, Rechler

Publikováno v: The Journal of biological chemistry. 268(13)

A family of six specific insulin-like growth factor binding proteins (IGFBPs) modulates the biological actions of the insulin-like growth factors, IGF-I and IGF-II. In the present study, we determined the binding affinity of purified human IGFBPs 1-6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::70ccf40471e2b0bc0ae553176743124f
https://pubmed.ncbi.nlm.nih.gov/7683646

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