Zobrazeno 1 - 10
of 67
pro vyhledávání: '"M. M. Oken"'
Autor:
John P. Gockerman, Bruce A. Peterson, George P. Canellos, David D. Hurd, Barbara A. Parker, M. M. Oken, B D Cheson, G Petroni, David B. Duggan, J Johnson, J Prchal, Sonali M. Smith
Publikováno v:
Leukemia & Lymphoma. 50:1606-1617
Recombinant interferon alpha-2b (IFN-alpha2) has direct and indirect antiproliferative effects in lymphoma, and may augment cytotoxicity when combined with chemotherapy. CALGB 8691 is a randomized study of daily oral cyclophosphamide (CPA) at 100 mg/
Autor:
P A, Cassileth, E, Lynch, J D, Hines, M M, Oken, J J, Mazza, J M, Bennett, P B, McGlave, M, Edelstein, D P, Harrington, M J, O'Connell
Publikováno v:
Blood. 79:1924-1930
The Eastern Cooperative Oncology Group (ECOG) conducted a randomized trial in patients less than or equal to 65 years old (median, 44 years) to determine whether increasing the intensity of postremission therapy in acute myeloid leukemia (AML) would
Publikováno v:
Cancer. 91(7)
The importance of the bone marrow microenvironment in multiple myeloma is receiving increasing attention. Recent studies have suggested the importance of cytokine production and cell-cell contact by bone marrow stromal cells in the survival of myelom
Autor:
M S, Tallman, D, Neuberg, J M, Bennett, C J, Francois, E, Paietta, P H, Wiernik, G, Dewald, P A, Cassileth, M M, Oken, J M, Rowe
Publikováno v:
Blood. 96(7)
Acute megakaryocytic leukemia (AMegL) is a rare subtype of acute myeloid leukemia (AML) evolving from primitive megakaryoblasts. Because of its rarity and the lack of precise diagnostic criteria in the past, few series of adults treated with contempo
Publikováno v:
British journal of haematology. 109(1)
Bone involvement is a central feature of multiple myeloma (MM). We investigated whether serum markers of osteoblastic and osteoclastic activity correlate with the presence of bone disease and survival in 313 MM patients enrolled in a phase III trial
Publikováno v:
British journal of haematology. 100(3)
T-helper blood populations are frequently altered in multiple myeloma (MM). We measured the numbers of naive and activated cell subsets in the blood of a cohort of both previously untreated and treated MM patients. Two-colour flow cytometry to detect
Autor:
J N, Winter, J, Andersen, J C, Reed, S, Krajewski, D, Variakojis, K D, Bauer, R I, Fisher, L I, Gordon, M M, Oken, S, Jiang, D, Jeffries, P, Domer
Publikováno v:
Blood. 91(4)
An inverse relationship between BCL-2 expression and cell cycle transition has been suggested by recent studies in murine models. To investigate the clinical relevance of these laboratory studies, a group of 116 paraffin-embedded non-Hodgkin's lympho
Publikováno v:
Cancer. 79(8)
The Eastern Cooperative Oncology Group (ECOG) performed a Phase III comparison of melphalan and prednisone (MP) with vincristine, carmustine (BCNU), melphalan, cyclophosphamide, and prednisone (VBMCP) in an attempt to determine which of these regimen
Publikováno v:
Journal of immunotherapy (Hagerstown, Md. : 1997). 20(2)
Interferon-gamma (IFN-gamma) has the most potent immunomodulatory activity of all the interferons. This phase II-B study was performed to define time- and dose-dependent immunomodulatory effects mediated by IFN-gamma in a subset of patients with mela
Autor:
J N, Winter, J, Andersen, D, Variakojis, L I, Gordon, R I, Fisher, M M, Oken, R S, Neiman, S, Jiang, K D, Bauer
Publikováno v:
Blood. 88(10)
The International Index is a powerful predictor of outcome in the aggressive non-Hodgkin's lymphomas that is based solely on clinical features. Proliferative activity (% S-phase) measured by flow cytometry has been reported to have prognostic signifi