Zobrazeno 1 - 10
of 174
pro vyhledávání: '"M. M. Lederman"'
Autor:
S. S. Mahalingam, S. Jayaraman, N. Bhaskaran, E. Schneider, F. Faddoul, A. Paes da Silva, M. M. Lederman, R. Asaad, K. Adkins-Travis, L. P. Shriver, P. Pandiyan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Polyamine metabolism is a determinant of T helper cell polarization. Here, Mahalingam et al analyse the metabolic and transcriptomic profile of oral mucosa from people living with HIV to demonstrate the effect of polyamine synthesis on T cell dysfunc
Externí odkaz:
https://doaj.org/article/2ba00e0c03a14856be1e57d5a6dc3f18
Autor:
N. Bhaskaran, E. Schneider, F. Faddoul, A. Paes da Silva, R. Asaad, A. Talla, N. Greenspan, A. D. Levine, D. McDonald, J. Karn, M. M. Lederman, P. Pandiyan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Anti-retroviral treatment does not fully resolve mucosal dysfunction and systemic inflammation in HIV infected individuals. Authors show here that an unusual population of regulatory T cells, distinguished by Amphiregulin expression and the incapabil
Externí odkaz:
https://doaj.org/article/f84dc4b52eef4e9586846ddf93c4213d
Autor:
N, Bhaskaran, E, Schneider, F, Faddoul, A, Paes da Silva, R, Asaad, A, Talla, N, Greenspan, A D, Levine, D, McDonald, J, Karn, M M, Lederman, P, Pandiyan
Publikováno v:
Nature Communications
Residual systemic inflammation and mucosal immune dysfunction persist in people living with HIV, despite treatment with combined anti-retroviral therapy, but the underlying immune mechanisms are poorly understood. Here we report that the altered immu
Autor:
C T, Longenecker, N T, Funderburg, Y, Jiang, S, Debanne, N, Storer, D E, Labbato, M M, Lederman, G A, McComsey
Publikováno v:
HIV medicine. 14(6)
The aim of the study was to explore the relationships between lymphocyte and monocyte activation, inflammation, and subclinical vascular disease among HIV-1-infected patients on antiretroviral therapy (ART).Baseline mean common carotid artery (CCA) i
Autor:
A C, Collier, L A, Kalish, M P, Busch, T, Gernsheimer, S F, Assmann, T A, Lane, D M, Asmuth, M M, Lederman, E L, Murphy, P, Kumar, M, Kelley, T P, Flanigan, D K, McMahon, H S, Sacks, M S, Kennedy, P V, Holland
Publikováno v:
JAMA. 285(12)
Allogeneic blood transfusions have immunomodulatory effects and have been associated with activation of human immunodeficiency virus (HIV) and cytomegalovirus (CMV) in vitro and of HIV in small pilot studies. Retrospective studies suggest that transf
Autor:
M M, Lederman, H, Valdez
Publikováno v:
AIDS clinical review.
Autor:
M M, Lederman
Publikováno v:
The AIDS reader. 10(4)
Although HAART restores immune function in patients with HIV infection, restoration is incomplete. Functional restoration is seen primarily in responses to antigens that are prevalent in HIV-infected persons. Immunization is required to restore respo
Autor:
D R, Kuritzkes, A, Sevin, B, Young, M, Bakhtiari, H, Wu, M, St Clair, E, Connick, A, Landay, J, Spritzler, H, Kessler, M M, Lederman
Publikováno v:
The Journal of infectious diseases. 181(2)
The effect of baseline drug resistance mutations on response to zidovudine, lamivudine, and ritonavir was evaluated in zidovudine-experienced persons infected with human immunodeficiency virus type 1 (HIV-1). Presence of the K70R mutation was associa
Autor:
C A, Benson, P L, Williams, D L, Cohn, S, Becker, P, Hojczyk, T, Nevin, J A, Korvick, L, Heifets, C C, Child, M M, Lederman, R C, Reichman, W G, Powderly, G F, Notario, B A, Wynne, R, Hafner
Publikováno v:
The Journal of infectious diseases. 181(4)
The efficacy and safety of clarithromycin and rifabutin alone and in combination for prevention of Mycobacterium avium complex (MAC) disease were compared in 1178 patients with AIDS who hador =100 CD4 T cells/microL in a randomized, double-blind, pla
Publikováno v:
AIDS (London, England). 12(18)