Zobrazeno 1 - 10
of 28
pro vyhledávání: '"M. M. Guzyk"'
Autor:
O. I. Krynina, S. I. Romaniuk, O. B. Gorbatiuk, O. H. Korchynskyi, А. V. Rebriiev, Ya. S. Kulyk, Ye. O. Kozadaieva, A. A. Siromolot, M. M. Guzyk, D. V. Kolybo, S. V. Komisarenko
Publikováno v:
The Ukrainian Biochemical Journal, Vol 93, Iss 6, Pp 31-45 (2021)
The quickly emerged global COVID-19 pandemic raised a desperate need in the development of protecting vaccines targeting this disease. Therefore, a generation of effective producers of recombinant SARS-CoV-2 proteins became an urgent task. Its resolv
Externí odkaz:
https://doaj.org/article/6b30f382aa014b2689592a1b55e4c557
Autor:
M. M. Guzyk, T. M. Tykhonenko, K. O. Dyakun, L. V. Yanitska, I. B. Pryvrotska, T. M. Kuchmerovska
Publikováno v:
The Ukrainian Biochemical Journal, Vol 91, Iss 1, Pp 21-29 (2019)
The molecular pathogenesis of diabetic encephalopathy (DE), one of the serious complications of diabetes mellitus, is complex. In this study, we examined whether expression levels of SIRT1 and SIRT2 were the key for the development of brain dysfuncti
Externí odkaz:
https://doaj.org/article/fd6d51925e7340a29387c4c2baa96588
Publikováno v:
The Ukrainian Biochemical Journal, Vol 90, Iss 6, Pp 31-40 (2018)
Reactive oxygen species (ROS) are considered to be important signalling molecules controlling many platelet functions. ROS production has been shown to be augmented by platelet activation, however, plasminogen (Pg) has not been studied in the context
Externí odkaz:
https://doaj.org/article/50aabc5305584f07a9ccda8cd5a466ab
Publikováno v:
The Ukrainian Biochemical Journal, Vol 89, Iss SI01, Pp 102-110 (2017)
Plasminogen/plasmin system is known for its ability to support hemostatic balance of blood. However, plasminogen may be considered as an adhesive ligand and in this way could affect the functioning of blood cells. We showed that exogenous Lys-plasmin
Externí odkaz:
https://doaj.org/article/0a3728f286e645cfbd1710e3a718bee7
Publikováno v:
Біологічні студії, Vol 8, Iss 3-4, Pp 41-52 (2014)
The effect of nicotinamide, acetyl-L-carnitine and α-lipoic acid on the separate links of carbohydrate metabolism in the brain, heart and liver of rats for type 2 diabetes it was investigated. Combined administration of nicotinamide, acetyl-L-carnit
Externí odkaz:
https://doaj.org/article/5f1d6893313142ceb8e1acaf34a166e3
Publikováno v:
The Ukrainian Biochemical Journal, Vol 86, Iss 4, Pp 138-149 (2014)
Connective tissue is highly susceptible to imbalances induced by diabetes. Diabetes-related osteopenia, decreased bone strength etc. may be associated with altered metabolism of various collagens. Although it is assumed that alterations in collagen a
Externí odkaz:
https://doaj.org/article/84919ae30d8649f2bc4ede55ab44369f
Publikováno v:
The Ukrainian Biochemical Journal, Vol 85, Iss 1, Pp 62-70 (2013)
The study was undertaken to investigate the influence of specific inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1), in particular nicotinamide and 1,5-isoqinolinediol on white blood cells of rats with diabetes. Using the fluorescent probe 2′,7
Externí odkaz:
https://doaj.org/article/5008b7446669487bae2de58f42f4fd0b
Autor:
M. M. Guzyk, Tetiana Tykhonenko, T. M. Kuchmerovska, I. B. Pryvrotska, L. V. Yanitska, Kateryna Diakun
Publikováno v:
Endocrine Regulations, Vol 55, Iss 2, Pp 61-71 (2021)
Objectives. The present study was designed to assess whether apoptosis-related genes as parp-1 and bax could be targets for treatment of diabetes mellitus and whether vitamin D may exert beneficial effects. Methods. Vitamin D3 treatment for 4 weeks,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e2517617961f16337d8e700ca734ff
https://doaj.org/article/1c73dcfeb99a4c29b8491d53db56ff95
https://doaj.org/article/1c73dcfeb99a4c29b8491d53db56ff95
Autor:
A. A. Tykhomyrov, Oleksii Goncharuk, S. I. Savosko, V.V. Medvediev, Yuri Chaikovsky, M. M. Guzyk, Vitaliy Tsymbaliuk
Publikováno v:
Journal of neurological surgery. Part A, Central European neurosurgery.
Fibrosis of the injured muscles is a problem of recovery from trauma and denervation. The aim of the work was to investigate the interconnection of matrix metalloproteinase-9 (ММР-9) activity in denervated muscles with fibrosis and to estimate its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0321214d9fcdc80eddb7a1333182ad6f
https://pubmed.ncbi.nlm.nih.gov/34496416
https://pubmed.ncbi.nlm.nih.gov/34496416
Autor:
I. B. Pryvrotska, K. O. Dyakun, T. M. Kuchmerovska, L. V. Yanitska, M. M. Guzyk, T. M. Tykhonenko
Publikováno v:
Ukrainian Biochemical Journal, Vol 91, Iss 1, Pp 21-29 (2019)
The molecular pathogenesis of diabetic encephalopathy (DE), one of the serious complications of diabetes mellitus, is complex. In this study, we examined whether expression levels of SIRT1 and SIRT2 were the key for the development of brain dysfuncti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8579d7548db67c8e19d99c4687882d3
http://ukrbiochemjournal.org/wp-content/uploads/2019/01/Guzyk_1_19.pdf
http://ukrbiochemjournal.org/wp-content/uploads/2019/01/Guzyk_1_19.pdf