Zobrazeno 1 - 10
of 227
pro vyhledávání: '"M. M. Exner"'
Autor:
M A Lewinski, M M Exner
Publikováno v:
Molecular and Cellular Probes. 16:351-357
The introduction of multiplex PCR techniques to clinical laboratories has provided a means to streamline assays and to produce multiple results with minimal effort. While this methodology is very beneficial, care must be taken to ensure that reaction
Publikováno v:
Infection and Immunity. 68:2647-2654
Oms66 is aBorrelia burgdorferiouter membrane porin protein whose role in Lyme disease pathogenesis and immunity has not been well established. Oms66 was solubilized from whole-cell lysates of strain B313 (which is derived from B31 but lacks OspA, -B,
Autor:
Hongwei H. Zhang, M. M. Exner, David R. Blanco, Michael Lovett, James N. Miller, Martin L. Phillips, Cheryl I. Champion, Ellen S. Shang
Publikováno v:
Journal of Bacteriology. 181:7168-7175
We have previously observed that while native Treponema pallidum rare outer membrane protein 1 (Tromp1) is hydrophobic and has porin activity, recombinant forms of Tromp1 do not possess these properties. In this study we show that these properties ar
Autor:
Ellen S. Shang, Bruce L. Kagan, M. M. Exner, Michael Lovett, James N. Miller, Jonathan T. Skare, David R. Blanco
Publikováno v:
Infection and Immunity. 66:1082-1091
The outer membrane of Borrelia hermsii has been shown by freeze-fracture analysis to contain a low density of membrane-spanning outer membrane proteins which have not yet been isolated or identified. In this study, we report the purification of outer
Publikováno v:
Journal of Bacteriology. 177:5447-5452
Helicobacter pylori is a causative agent of gastritis in humans and is correlated with gastric ulcer formation. Infections with this bacterium have proven difficult to treat with antimicrobial agents. To better understand how this bacterium transport
Autor:
H Erdjument-Bromage, M. M. Exner, Cheryl I. Champion, David R. Blanco, James N. Miller, P Tempst, Michael A. Lovett, R. E. W. Hancock
Publikováno v:
Journal of Bacteriology. 177:3556-3562
We have recently reported the isolation and purification of the Treponema pallidum outer membrane and the identification of its rare protein constituents, including a 31-kDa protein markedly enriched in the outer membrane preparation (D.R. Blanco, K.
Autor:
Cheryl I. Champion, R. E. W. Hancock, H Erdjument-Bromage, David R. Blanco, Michael A. Lovett, M. M. Exner, P Tempst, James N. Miller
Publikováno v:
Journal of bacteriology. 179(4)
In this study, we report the cloning, sequencing, and expression of the gene encoding a 28-kDa Treponema pallidum subsp. pallidum rare outer membrane protein (TROMP), designated Tromp2. The tromp2 gene encodes a precursor protein of 242 amino acids i
Autor:
Jon T. Skare, James N. Miller, R. E. W. Hancock, Cheryl I. Champion, David R. Blanco, Michael A. Lovett, Ellen S. Shang, M. M. Exner
Publikováno v:
Journal of bacteriology. 178(23)
We recently reported the cloning and sequencing of the gene encoding a 31-kDa Treponema pallidum subsp. pallidum rare outer membrane porin protein, designated Tromp1 (D. R. Blanco, C. I. Champion, M. M. Exner, H. Erdjument-Bromage, R. E. W. Hancock,
Publikováno v:
Infection and immunity. 63(8)
A protein with an apparent M(r) of 28,000 was isolated from outer membrane preparations of Aeromonas salmonicida A440. The protein was tested for the ability to form pores, using a planar lipid bilayer model membrane system. The protein appeared to b
Autor:
T. A. Summers, R. E. W. Hancock, David A. Haake, Ellen S. Shang, Cheryl I. Champion, M. M. Exner, C. Martinich
Publikováno v:
Infection and immunity. 63(8)
The outer membranes of invasive spirochetes contain unusually small amounts of transmembrane proteins. Pathogenic Leptospira species produce a rare 31-kDa surface protein, OmpL1, which has a deduced amino acid sequence predictive of multiple transmem