Zobrazeno 1 - 2
of 2
pro vyhledávání: '"M. M. C. G. Peters"'
Autor:
P. A. Van Elburg, N. J. Van Sittert, K. A. Richardson, R. H. J. J. J. Megens, James A. Bond, Peter J. Boogaard, Michele A. Medinsky, William P. Watson, M. M. C. G. Peters, Ewan D. Booth, Brian A. Wong
Publikováno v:
Toxicological Sciences. 49:186-201
1,3-Butadiene (butadiene) is a potent carcinogen in mice, but not in rats. Metabolic studies may provide an explanation of these species differences and their relevance to humans. Male Sprague-Dawley rats and B6C3F1 mice were exposed for 6 h to 200 p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95fe09066f696e29a0e0c7ed4db040c
https://doi.org/10.1093/toxsci/49.2.186
https://doi.org/10.1093/toxsci/49.2.186
Autor:
Bernard T. Golding, N. J. Van Sittert, K. A. Richardson, Peter J. Boogaard, P. A. Van Elburg, William P. Watson, R. H. J. J. J. Megens, M. M. C. G. Peters
Publikováno v:
Chemical research in toxicology. 11(12)
Differences in the metabolism of 1,3-butadiene (Bd) in rats and mice may account for the observed species difference in carcinogenicity. Previous studies of the metabolic fate of Bd have identified epoxide formation as a key metabolic transformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f78435844eedbc39083b4dbacf3715
https://pubmed.ncbi.nlm.nih.gov/9860500
https://pubmed.ncbi.nlm.nih.gov/9860500