Zobrazeno 1 - 10
of 55
pro vyhledávání: '"M. Lynn Lamoreux"'
Autor:
Danièle Tenza, Steven T. Truschel, Dorothy C. Bennett, M. Lynn Lamoreux, Graça Raposo, Evelyn Chou, Alexander C. Theos, Marta Starcevic, Santiago M. Di Pietro, Subba Rao Gangi Setty, Elena V. Sviderskaya, Michael S. Marks, Esteban C. Dell'Angelica
Publikováno v:
Molecular Biology of the Cell
Hermansky-Pudlak syndrome (HPS) is a genetic disorder characterized by defects in the formation and function of lysosome-related organelles such as melanosomes. HPS in humans or mice is caused by mutations in any of 15 genes, five of which encode sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c267b753fc5cb8ae28b18ce9ea50c1
https://doi.org/10.1091/mbc.e06-12-1066
https://doi.org/10.1091/mbc.e06-12-1066
Autor:
Kazumasa Wakamatsu, Francisco Solano, M. Lynn Lamoreux, Shosuke Ito, Gertrude-E. Costin, Adina L. Milac, Yuji Yamaguchi, Vincent J. Hearing, Andrei J. Petrescu, Francois Rouzaud, Wilfred D. Vieira, Julio C. Valencia
Publikováno v:
Biochemical Journal. 391:249-259
Dopachrome tautomerase (Dct) is a type I membrane protein and an important regulatory enzyme that plays a pivotal role in the biosynthesis of melanin and in the rapid metabolism of its toxic intermediates. Dct-mutant melanocytes carrying the slaty or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3878d2d5853a9dd04d031d38ca2d76e7
https://doi.org/10.1042/bj20042070
https://doi.org/10.1042/bj20042070
Autor:
Elena V. Sviderskaya, Richard A. Spritz, Songtao Ben, Edward K. Novak, Kazumasa Wakamatsu, William A. Gahl, Wei Li, Sreenivasulu Chintala, Young-Mee Park, Richard T. Swank, Dorothy C. Bennett, Shosuke Ito, Jian Tan, M. Lynn Lamoreux, Marjan Huizing
Publikováno v:
Proceedings of the National Academy of Sciences. 102:10964-10969
In mammals, >100 genes regulate pigmentation by means of a wide variety of developmental, cellular, and enzymatic mechanisms. Nevertheless, genes that directly regulate pheomelanin production have not been described. Here, we demonstrate that the sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c2f00d4d57ca83e6bdb6c89c84728e
https://doi.org/10.1073/pnas.0502856102
https://doi.org/10.1073/pnas.0502856102
Publikováno v:
Pigment Cell Research. 18:64-73
For the study of development of pigmentation, compared with mammalian models, fish offer the advantage of multiple chromatophore types and ready access to the developing embryo for observation and experimental manipulation. Compared with zebrafish em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef4445282a316237b1a8ead26180854b
https://doi.org/10.1111/j.1600-0749.2005.00216.x
https://doi.org/10.1111/j.1600-0749.2005.00216.x
Autor:
Wilfred D. Vieira, M. Lynn Lamoreux, Gertrude-E. Costin, Francois Rouzaud, Julio C. Valencia, Vincent J. Hearing
Publikováno v:
Analytical Biochemistry. 335:171-174
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca56e9b730a5970068b1436b824fa608
https://doi.org/10.1016/j.ab.2004.07.035
https://doi.org/10.1016/j.ab.2004.07.035
Autor:
Keisuke Oboki, Tomohiko Wakayama, Yukihiko Kitamura, Yu-ichiro Koma, Tomoko Jippo, Eiichi Morii, M. Lynn Lamoreux, Akihiko Ito, Shoichi Iseki
Publikováno v:
The American Journal of Pathology. 165:491-499
The mi (microphthalmia) locus of mice encodes a transcription factor, MITF. B6-tg/tg mice that do not express any MITF have white coats and small eyes. Moreover, the number of mast cells decreased to one-third that of normal control (+/+) mice in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24046efab306256fc668ffdb15d02e82
https://doi.org/10.1016/s0002-9440(10)63314-7
https://doi.org/10.1016/s0002-9440(10)63314-7
Autor:
Eiríkur Steingrímsson, Nancy A. Jenkins, Neal G. Copeland, Heinz Arnheiter, Jón Hallsteinn Hallsson, M. Lynn Lamoreux
Publikováno v:
Genetics. 163:267-276
Mutations at the mouse microphthalmia locus (Mitf) affect the development of different cell types, including melanocytes, retinal pigment epithelial cells of the eye, and osteoclasts. The MITF protein is a member of the MYC supergene family of basic-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d811bb6c22bb0fc7ea9252029cd5c81c
https://doi.org/10.1093/genetics/163.1.267
https://doi.org/10.1093/genetics/163.1.267
Autor:
Shintaro Nomura, Tomoko Jippo, M. Lynn Lamoreux, Eiichi Morii, Yukihiko Kitamura, Dae-Ki Kim, Keisuke Oboki, Young-Mi Lee, Hideki Ogihara, Akihiko Ito, Kazutaka Maeyama
Publikováno v:
Blood. 97:2038-2044
The mi transcription factor (MITF) is a basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factor that is important for the development of mast cells. Mast cells of mi/mi genotype express normal amount of abnormal MITF (mi-MITF), whereas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e14b29c7353bb2ee6b406c1a1c27d2b
https://doi.org/10.1182/blood.v97.7.2038
https://doi.org/10.1182/blood.v97.7.2038
Autor:
M. Lynn Lamoreux
Publikováno v:
Pigment Cell Research. 13:421-430
Pigment mutations in inbred mice have been important to many new scientific developments over the past century. Inbred mice are essentially genetically alike because of 10-20 generations or more of sibling mating or the equivalent. Mice of the same i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed593f84021ed784ca9a7b8d16a360a2
https://doi.org/10.1034/j.1600-0749.2000.130603.x
https://doi.org/10.1034/j.1600-0749.2000.130603.x