Zobrazeno 1 - 10
of 132
pro vyhledávání: '"M. Luijendijk"'
Autor:
Louisa E. Linders, Lefkothea Patrikiou, Mariano Soiza-Reilly, Evelien H. S. Schut, Bram F. van Schaffelaar, Leonard Böger, Inge G. Wolterink-Donselaar, Mieneke C. M. Luijendijk, Roger A. H. Adan, Frank J. Meye
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Stress can increase the consumption of rewarding food, which contributes to obesity and binge eating disorders. Here the authors show that stress eating depends on a strengthened connection between the lateral hypothalamus and the dopamine system.
Externí odkaz:
https://doaj.org/article/9ba1965f6c544a44a4537127a8c9383f
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Leptin exerts its effects on energy balance by inhibiting food intake and increasing energy expenditure via leptin receptors in the hypothalamus. While LepR neurons in the arcuate nucleus of the hypothalamus, the primary target of leptin, ha
Externí odkaz:
https://doaj.org/article/8f33abfdc0e242afb1bb2b1d18736e5c
Autor:
Theresia J. M. Roelofs, Shanice Menting-Henry, Lieke M. Gol, Annelijn M. Speel, Vera H. Wielenga, Keith M. Garner, Mieneke C. M. Luijendijk, Alexandru A. Hennrich, Karl-Klaus Conzelmann, Roger A. H. Adan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The lateral hypothalamus (LH) is critically involved in the regulation of homeostatic energy balance. Some neurons in the LH express receptors for leptin (LepRb), a hormone known to increase energy expenditure and decrease energy intake. How
Externí odkaz:
https://doaj.org/article/793b513311984bcbaeb6246069be3a08
Autor:
Véronne A. J. de Vrind, Lisanne J. van ‘t Sant, Annemieke Rozeboom, Mieneke C. M. Luijendijk-Berg, Azar Omrani, Roger A. H. Adan
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Leptin is an anorexigenic hormone, important in the regulation of body weight. Leptin plays a role in food reward, feeding, locomotion and anxiety. Leptin receptors (LepR) are expressed in many brain areas, including the midbrain. In most studies tha
Externí odkaz:
https://doaj.org/article/942e31122b544d66b1392de19bec7e75
Autor:
Jeroen P. H. Verharen, Johannes W. de Jong, Theresia J. M. Roelofs, Christiaan F. M. Huffels, Ruud van Zessen, Mieneke C. M. Luijendijk, Ralph Hamelink, Ingo Willuhn, Hanneke E. M. den Ouden, Geoffrey van der Plasse, Roger A. H. Adan, Louk J. M. J. Vanderschuren
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Aberrant increased dopaminergic function results in impaired value-based decision making. Here the authors report pathway-specific effects of VTA activation on distinct aspects of flexible value-based decisions in rats.
Externí odkaz:
https://doaj.org/article/31622733c1f8444ca230c79f49f730a9
Autor:
Kathy C.G. deGit, Johannes A. denOuter, Inge G. Wolterink‐Donselaar, Mieneke C. M. Luijendijk, Erik Schéle, Suzanne L. Dickson, Roger A. H. Adan
Publikováno v:
Physiological Reports, Vol 7, Iss 14, Pp n/a-n/a (2019)
Abstract Both feeding behavior and thermogenesis are regulated by leptin. The sensitivity to leptin's anorexigenic effects on chow diet was previously shown to predict the development of diet‐induced obesity. In this study, we determined whether th
Externí odkaz:
https://doaj.org/article/45f97b55e5e44b23982f647b805a8645
Autor:
Nefeli Kakava-Georgiadou, Maria M. Zwartkruis, Clara Bullich-Vilarrubias, Mieneke C. M. Luijendijk, Keith M. Garner, Geoffrey van der Plasse, Roger A. H. Adan
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Development of tools to manipulate activity of specific neurons is important for dissecting the function of neural circuits. Viral vectors and conditional transgenic animal lines that target recombinases to specific cells facilitate the successful ma
Externí odkaz:
https://doaj.org/article/eec5557d9899403bacbfd9f1f042c672
Autor:
Jacques P. Flores-Dourojeanni, Marleen H. van den Munkhof, Mieneke C. M. Luijendijk, Louk J. M. J. Vanderschuren, Roger A. H. Adan
Exaggerated impulsivity and attentional impairments are hallmarks of certain disorders of behavioural control such as attention-deficit/hyperactivity disorder (ADHD), schizophrenia and addiction. Pharmacological studies have implicated elevated dopam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146416941d469e3d89c5a86ee780a71d
https://dspace.library.uu.nl/handle/1874/429473
https://dspace.library.uu.nl/handle/1874/429473
Akademický článek
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Autor:
Iris Stoltenborg, Inge G. Wolterink-Donselaar, Roger A.H. Adan, Frank J. Meye, Azar Omrani, Suzanne L. Dickson, Karlijn Liselotte Kooij, Keith M. Garner, Véronne A J de Vrind, Lisanne J. van ’t Sant, Bart Lodder, Mieneke C M Luijendijk-Berg, Annemieke Rozeboom
Publikováno v:
Biological Psychiatry. 90:843-852
Background Leptin reduces the motivation to obtain food by modulating activity of the mesolimbic dopamine (DA) system upon presentation of cues that predict a food reward. Although leptin directly reduces the activity of ventral tegmental area (VTA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6e133d3c8579a4d8f30db8e4aa09a6
https://doi.org/10.1016/j.biopsych.2021.02.017
https://doi.org/10.1016/j.biopsych.2021.02.017