Zobrazeno 1 - 10
of 21
pro vyhledávání: '"M. Luísa C. Vale"'
Autor:
Eduardo F. Marques, Raquel C. F. Gonçalves Lopes, M. Luísa C. Vale, Ana Rita Faria, Jana B. Nieder, Oscar F. Silvestre
Publikováno v:
Nanoscale. 11:5932-5941
Self-assembled vesicles composed of amino acid-based cationic/anionic surfactant mixtures show promise as novel effective drug nanocarriers. Here, we report the in vitro performance of vesicles based on cationic (16Ser) and anionic (8-8Ser) serine-ba
Autor:
Andreia C. Gomes, Catarina Costa, Eduardo F. Marques, Isabel S. Oliveira, Cláudia Botelho, Sandra G. Silva, M. Luísa C. Vale, João P. Silva, Maria Elisabete C.D. Real Oliveira
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Supplementary data to this article can be found online athttps://doi.org/10.1016/j.jcis.2020.09.077.
Non-viral gene therapy based on gene silencing with small interfering RNA (siRNA) has attracted great interest over recent years. Among various
Non-viral gene therapy based on gene silencing with small interfering RNA (siRNA) has attracted great interest over recent years. Among various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b90c487372c3949388ad9169d6a176
https://hdl.handle.net/1822/67465
https://hdl.handle.net/1822/67465
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 5, Pp o992-o993 (2009)
The title compound, C15H13N3O8, comprises two crystallographically independent molecules in the asymmetric unit. In the crystal, intermolecular C—H...O hydrogen bonds link the molecules and short C=O...π contacts are seen.
Externí odkaz:
https://doaj.org/article/036e5ac4b4fd4a6a9a517ec98fc9a971
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 1, Pp o188-o188 (2009)
In the title compound, C20H20NO4P, the dihedral angle between the phenyl rings is 68.52 (7)°. In the crystal structure, the molecules are linked by a weak C—H...π(arene) interaction along [010] involving the phenyl CH group and the phenyl rings.
Externí odkaz:
https://doaj.org/article/7267a5a50ca54771ae3d68a282efe653
Autor:
Sandra G. Silva, Catarina Costa, Vitor Francisco, Luis García-Río, Eduardo F. Marques, M. Luísa C. Vale
Publikováno v:
Colloids and Surfaces A: Physicochemical and Engineering Aspects. 480:71-78
Complex self-assembled structures can be built up in aqueous media by making use of non-covalent interactions between small organic molecules and conventional amphiphiles. The macrocycle p -sulfonatocalix[4]arene (SC4) is a known receptor for organic
Serine-based gemini surfactants with different spacer linkages: from self-assembly to DNA compaction
Publikováno v:
Soft Matter. 10:9352-9361
Cationic gemini surfactants have strong potential as compaction agents of nucleic acids for efficient non-viral gene delivery. In this work, we present the aggregation behavior of three novel cationic serine-based gemini surfactants as well as their
Autor:
Marina I. Giannotti, M. Luísa C. Vale, Eduardo F. Marques, Lorena Redondo-Morata, Lia M. C. Lima, Fausto Sanz
Publikováno v:
Langmuir. 29:9352-9361
The addition of surfactants to lipid bilayers is important for the modulation of lipid bilayer properties (e.g., in protein reconstitution and development of nonviral gene delivery vehicles) and to provide insight on the properties of natural biomemb
Autor:
Ana M. Cardoso, Amália S. Jurado, M. Luísa C. Vale, Maria C. Pedroso de Lima, Cláudia Alves, Sandra G. Silva, Eduardo F. Marques
Publikováno v:
European Journal of Organic Chemistry. 2013:1758-1769
Two series of novel cationic gemini surfactants based on the amino acid serine have been synthesized. These compounds contain long alkyl chains linked to the nitrogen atoms of the amino acid residues, as well as spacers interconnecting two carboxylic
Autor:
Olga Caamaño, Fabio Rizzo-Aguiar, José E. Rodríguez-Borges, Carlos Sousa, Xerardo García-Mera, M. Luísa C. Vale
Publikováno v:
Tetrahedron Letters. 53:1029-1032
A route to selective functionalization of polyhydroxypyrrolidines is described. The method is based on orthogonal protection/deprotection along the process of synthesis of the referred pyrrolidines, which consist in hydroxylation of the double bond o
Publikováno v:
Tetrahedron. 68:1682-1687
The acid catalyzed cycloaddition reaction of methyl glyoxylate oxime with cyclopentadiene (CPD) afforded the corresponding aza-Diels–Alder adducts, the endo and exo isomers of (±)-methyl 2-hydroxy-2-azabicyclo[2.2.1]hept-5-ene-3-carboxylates, and