Zobrazeno 1 - 10
of 2 053
pro vyhledávání: '"M. Loeb"'
Autor:
Matthew E. Randolph, Marwa Afifi, Aparna Gorthi, Rachel Weil, Breelyn A. Wilky, Joshua Weinreb, Paul Ciero, Natalie ter Hoeve, Paul J. van Diest, Venu Raman, Alexander J.R. Bishop, David M. Loeb
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108925- (2024)
Summary: We previously demonstrated that RNA helicase DDX3X (DDX3) can be a therapeutic target in Ewing sarcoma (EWS), but its role in EWS biology remains unclear. The present work demonstrates that DDX3 plays a unique role in DNA damage repair (DDR)
Externí odkaz:
https://doaj.org/article/feee3811ebda42bda24ca7644f0ec5fe
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/5ad19878a4654e2984c978ad70efa345
Autor:
Dana R. Warren, Harper M. Loeb, Peter Betjemann, Isabel A. Munck, William S. Keeton, David C. Shaw, Eleanor J. Harvey
Publikováno v:
Ecosphere, Vol 14, Iss 9, Pp n/a-n/a (2023)
Abstract As we contemplate the future of forest landscapes under changing climate conditions and land‐use demands, there is increasing value in studying historic forest conditions and how these landscapes have changed following past disturbances. H
Externí odkaz:
https://doaj.org/article/81ab61d967be4bf3a5cf176372409e10
Autor:
Brian Geohagen, Elizabeth Zeldin, Kimberly Reidy, Tao Wang, Evripidis Gavathiotis, Yonatan I. Fishman, Richard LoPachin, David M. Loeb, Daniel A. Weiser
Publikováno v:
Translational Oncology, Vol 27, Iss , Pp 101595- (2023)
Cisplatin is a widely used and efficacious chemotherapeutic agent for treating solid tumors, yet it causes systemic end-organ damage that is often irreversible and detrimental to quality of life. This includes severe sensorineural hearing loss, hepat
Externí odkaz:
https://doaj.org/article/ec03216d871649379ca0aac75ab5fa59
Autor:
Quy Le, Brandon Hadland, Jenny L. Smith, Amanda Leonti, Benjamin J. Huang, Rhonda Ries, Tiffany A. Hylkema, Sommer Castro, Thao T. Tang, Cyd N. McKay, LaKeisha Perkins, Laura Pardo, Jay Sarthy, Amy K. Beckman, Robin Williams, Rhonda Idemmili, Scott Furlan, Takashi Ishida, Lindsey Call, Shivani Srivastava, Anisha M. Loeb, Filippo Milano, Suzan Imren, Shelli M. Morris, Fiona Pakiam, Jim M. Olson, Michael R. Loken, Lisa Brodersen, Stanley R. Riddell, Katherine Tarlock, Irwin D. Bernstein, Keith R. Loeb, Soheil Meshinchi
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 22 (2022)
The CBFA2T3-GLIS2 (C/G) fusion is a product of a cryptic translocation primarily seen in infants and early childhood and is associated with dismal outcome. Here, we demonstrate that the expression of the C/G oncogenic fusion protein promotes the tran
Externí odkaz:
https://doaj.org/article/134ccd270d5242848fcfcd4f706249e4
Autor:
Dara G. Stockton, Anna K. Wallingford, Gabrielle Brind'amore, Lauren Diepenbrock, Hannah Burrack, Heather Leach, Rufus Isaacs, Lindsy E. Iglesias, Oscar Liburd, Francis Drummond, Elissa Ballman, Christelle Guedot, Janet Van Zoeren, Greg M. Loeb
Publikováno v:
Ecology and Evolution, Vol 10, Iss 14, Pp 7669-7685 (2020)
Abstract Overwintering Drosophila often display adaptive phenotypic differences beneficial for survival at low temperatures. However, it is unclear which morphological traits are the best estimators of abiotic conditions, how those traits are correla
Externí odkaz:
https://doaj.org/article/ae973f3c822a436d84199a1183324ed8
Autor:
Dara G. Stockton, Gregory M. Loeb
Publikováno v:
Frontiers in Ecology and Evolution, Vol 9 (2022)
Among insects, female oviposition preferences are critical to understanding the evolutionary dynamics between herbivores and hosts. Previous studies have shown Drosophila resource use has a strong genetic basis, although there is evidence that prefer
Externí odkaz:
https://doaj.org/article/d3cace2ffe99428a9501f8b3687f44f5
Autor:
Kyle M Lewald, Antoine Abrieux, Derek A Wilson, Yoosook Lee, William R Conner, Felipe Andreazza, Elizabeth H Beers, Hannah J Burrack, Kent M Daane, Lauren Diepenbrock, Francis A Drummond, Philip D Fanning, Michael T Gaffney, Stephen P Hesler, Claudio Ioriatti, Rufus Isaacs, Brian A Little, Gregory M Loeb, Betsey Miller, Dori E Nava, Dalila Rendon, Ashfaq A Sial, Cherre S Bezerra da Silva, Dara G Stockton, Steven Van Timmeren, Anna Wallingford, Vaughn M Walton, Xingeng Wang, Bo Zhao, Frank G Zalom, Joanna C Chiu
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 12 (2021)
Abstract Drosophila suzukiiD. suzukiiD. suzukii
Externí odkaz:
https://doaj.org/article/2d721061ec3e40ef80933108b5408be1
Autor:
Basia Galinski, Marcus Luxemburg, Yosef Landesman, Bruce Pawel, Katherine J. Johnson, Stephen R. Master, Kevin W. Freeman, David M. Loeb, Jean M. Hébert, Daniel A. Weiser
Publikováno v:
Translational Oncology, Vol 14, Iss 8, Pp 101114- (2021)
Across many cancer types in adults, upregulation of the nuclear-to-cytoplasmic transport protein Exportin-1 (XPO1) correlates with poor outcome and responsiveness to selinexor, an FDA-approved XPO1 inhibitor. Similar data are emerging in childhood ca
Externí odkaz:
https://doaj.org/article/df22e3a1000a4cbeba345adf608973b1
Autor:
Paola Barba, Rebecca Loughner, Karen Wentworth, Jan Peter Nyrop, Gregory M. Loeb, Bruce I. Reisch
Publikováno v:
Horticulture Research, Vol 6, Iss 1, Pp 1-12 (2019)
Abstract The abundance of predatory phytoseiid mites, Typhlodromus pyri, important biological control agents of spider mite pests in numerous crops, is positively influenced by the density of leaf trichomes and tuft-form domatia in vein axils. Identi
Externí odkaz:
https://doaj.org/article/cff7c548e636431887f89ed305085cb4