Zobrazeno 1 - 10
of 190
pro vyhledávání: '"M. Liscovitch"'
Autor:
W S Saltsman, W A Pedersen, M Liscovitch, P L Hudson, D T MacLaughlin, Patricia K. Donahoe, Jan Krzysztof Blusztajn
Publikováno v:
Journal of Biological Chemistry. 269:21885-21890
Receptor-activated breakdown of complex sphingolipids has been proposed as a mechanism for generating sphingoid base-containing putative second messenger molecules whose actions may modulate responses to extracellular signals. In human epidermoid car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42b55924ab10009abcdde9fd6c4230a3
https://doi.org/10.1016/s0021-9258(17)31885-9
https://doi.org/10.1016/s0021-9258(17)31885-9
Publikováno v:
Anticancer research. 21(2A)
Intrinsic or acquired resistance of tumor cells to multiple cytotoxic drugs (multidrug resistance MDR) is a major cause of failure of cancer chemotherapy. MDR is often caused by elevated expression of drug transporters such as P-glycoprotein (P-gp) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::54f6a7396355a5b152d825773fb3c216
https://pubmed.ncbi.nlm.nih.gov/11396162
https://pubmed.ncbi.nlm.nih.gov/11396162
Autor:
Y, Lavie, M, Liscovitch
Publikováno v:
Glycoconjugate journal. 17(3 -4)
The carcinogenic process involves a complex series of genetic and biochemical changes that enables transformed cells to proliferate, migrate to secondary sites and, in some cases, acquire mechanisms that make cancer cells resistant to chemotherapy. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::57ce7711b85dab2b82a79452c9afe952
https://pubmed.ncbi.nlm.nih.gov/11201798
https://pubmed.ncbi.nlm.nih.gov/11201798
Publikováno v:
The Journal of biological chemistry. 274(5)
The activation of cellular phospholipase D (PLD) is implicated in vesicular trafficking and signal transduction. Two mammalian PLD forms, designated PLD1 and PLD2, have been cloned, but their cellular localization and function are not fully understoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4242dbaaaa54ca8ea09e6fe261dd2970
https://pubmed.ncbi.nlm.nih.gov/9915802
https://pubmed.ncbi.nlm.nih.gov/9915802
Publikováno v:
Neurochemical research. 23(5)
A partially purified rat brain membrane phospholipase D (PLD) activity was characterized in a mixed micellar system consisting of 1-palmitoyl-2-[6-N-(7-nitrobenzo-2-oxa-1,3-diazol-4-yl)-amino]capr oyl-phosphatidylcholine (NBD-PC) and Triton X-100, un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42e9d3201fb4922cd28ce68f196a32da
https://pubmed.ncbi.nlm.nih.gov/9566596
https://pubmed.ncbi.nlm.nih.gov/9566596
Publikováno v:
Endocrinology. 135(3)
The activation of phospholipase-D (PLD) was previously implicated in mediating the differentiative action of GnRH on preovulatory granulosa cells. The activation of PLD and the action of its product, phosphatidic acid (PA), were further studied in pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4c0815e457417c0581a275ca0248b8
https://pubmed.ncbi.nlm.nih.gov/8070364
https://pubmed.ncbi.nlm.nih.gov/8070364
Autor:
P L, Hudson, W A, Pedersen, W S, Saltsman, M, Liscovitch, D T, MacLaughlin, P K, Donahoe, J K, Blusztajn
Publikováno v:
The Journal of biological chemistry. 269(34)
Receptor-activated breakdown of complex sphingolipids has been proposed as a mechanism for generating sphingoid base-containing putative second messenger molecules whose actions may modulate responses to extracellular signals. In human epidermoid car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::33e4f05b2a11e7c72b83946f565eb047
https://pubmed.ncbi.nlm.nih.gov/8063833
https://pubmed.ncbi.nlm.nih.gov/8063833
Publikováno v:
Journal of lipid mediators. 8(3)
Studies carried out in many laboratories have demonstrated the activation of phospholipase D (PLD) by a variety of receptor agonists and in many cell types. The signal-dependent formation of phosphatidic acid (PA), by PLD-catalyzed hydrolysis of phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::25ba0595ad3e4465f0c36373cf10dcc1
https://pubmed.ncbi.nlm.nih.gov/8268464
https://pubmed.ncbi.nlm.nih.gov/8268464
Autor:
U. I. Richardson, J. K. Blusztajn, Mary Logue, J. H. Growdon, C. Mauron, I. L. G-Coviella, I. Ulus, M. Liscovitch, H.-C. Lee, Richard J. Wurtman
Publikováno v:
Demenz ISBN: 9783642769337
Die Herabsetzung der Aktivitat der Cholinacetyltransferase [des die Synthese von Acetylcholin (ACh) katalysierenden Enzyms] wurde als erstes der zahlreichen Neurotransmitteranomalien, die in den Gehirnen von Alzheimer-Patienten nachweisbar sind, besc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f10ce3a6c56e093a6a46ca39f3494b5
https://doi.org/10.1007/978-3-642-76932-0_8
https://doi.org/10.1007/978-3-642-76932-0_8
Autor:
Y Eli, M Liscovitch
Publikováno v:
Cell regulation. 2(12)
We have investigated the regulation of phospholipase D (PLD) activity by guanine nucleotides and Ca2+ in cells of the NG108-15 neuroblastoma X glioma line that were permeabilized with digitonin. The nonhydrolyzable GTP analogue guanosine-5'-O-(3-thio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d0b50f10b72ea2e6d4e83bbd695ce7
https://pubmed.ncbi.nlm.nih.gov/1801922
https://pubmed.ncbi.nlm.nih.gov/1801922