Zobrazeno 1 - 10
of 16
pro vyhledávání: '"M. Leslie Fulcher"'
Autor:
Amy C. Sims, Hugh D. Mitchell, Lisa E. Gralinski, Jennifer E. Kyle, Kristin E. Burnum-Johnson, Mariam Lam, M. Leslie Fulcher, Ande West, Richard D. Smith, Scott H. Randell, Thomas O. Metz, Timothy P. Sheahan, Katrina M. Waters, Ralph S. Baric
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Tissue- and cell-specific expression patterns are highly variable within and across individuals, leading to altered host responses after acute virus infection. Unraveling key tissue-specific response patterns provides novel opportunities for
Externí odkaz:
https://doaj.org/article/a299fa7ab51f41d792827fb0f696c144
Autor:
Jacob Kocher, Leslee Arwood, Rachel C. Roberts, Ibrahim Henson, Abigail Annas, David Emerson, Nathan Stasko, M. Leslie Fulcher, Marisa Brotton, Scott H. Randell, Adam S. Cockrell
Publikováno v:
bioRxiv
The emergence of SARS-CoV-2 variants that evade host immune responses has prolonged the COVID-19 pandemic. Thus, the development of an efficacious, variant-agnostic therapeutic for the treatment of early SARS-CoV-2 infection would help reduce global
Autor:
Mariam Lam, Lisa E. Gralinski, Katrina M. Waters, Timothy P. Sheahan, Richard D. Smith, Hugh D. Mitchell, Scott H. Randell, Thomas O. Metz, Ande West, Ralph S. Baric, M. Leslie Fulcher, Amy C. Sims, Kristin E. Burnum-Johnson, Jennifer E. Kyle
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
mBio
mBio
Tissue- and cell-specific expression patterns are highly variable within and across individuals, leading to altered host responses after acute virus infection. Unraveling key tissue-specific response patterns provides novel opportunities for defining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9db00d2c66c8d1f6e358357798e071
Autor:
Uma M. Nagarajan, Catherine M. O'Connell, M. Leslie Fulcher, Kate Patton, Bryan E. McQueen, Scott H. Randell, Mehmet Kesimer, Emily Powell, Amy Kiatthanapaiboon, Mariam Lam, Priscilla B. Wyrick, Boris Reidel, Victoria J. Madden, Avinash Kollipara, Toni Darville, Robert J. Suchland
Publikováno v:
Infect Immun
Chlamydia trachomatis infection of the human fallopian tubes can lead to damaging inflammation and scarring, ultimately resulting in infertility. To study the human cellular responses to chlamydial infection, researchers have frequently used transfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c43f273846a11a5bd2778903f6324a9
https://europepmc.org/articles/PMC7440757/
https://europepmc.org/articles/PMC7440757/
Autor:
Ling Sun, Richard C. Boucher, Alessandra Livraghi-Butrico, Purushothama Rao Tata, Kenichi Okuda, Luther A. Bartelt, Aravinda M. de Silva, Mark J. Cameron, Nathan I. Nicely, Adam J. Kimple, Ross E. Zumwalt, Andrew J. Ghio, Takanori Asakura, Hong Dang, Vishwaraj Sontake, Sarah R. Leist, David J. Kelvin, Alain C. Borczuk, Kenneth H. Dinnon, Kenneth N. Olivier, Longping V. Tse, Wanda K. O'Neal, Teresa M. Mascenik, M. Leslie Fulcher, Scott H. Randell, Caitlin E. Edwards, Takafumi Kato, Lisa E. Gralinski, Cheryl M. Cameron, David R. Martinez, Rodney C. Gilmore, Alexandra Schäfer, Ilona Jaspers, Yixuan J. Hou, Ralph S. Baric, Alena J. Markmann, Rhianna E. Lee, David M. Margolis, Steven P. Salvatore, Satoko Nakano, Gang Chen, Fernando J. Martinez, Boyd Yount
Publikováno v:
Cell
The mode of acquisition and causes for the variable clinical spectrum of coronavirus disease 2019 (COVID-19) remain unknown. We utilized a reverse genetics system to generate a GFP reporter virus to explore severe acute respiratory syndrome coronavir
Autor:
Lisa C. Jones, Wanda K. O'Neal, Yunxiang Zhu, Eduardo R. Lazarowski, Richard C. Boucher, Lama Moussa, Silvia M. Kreda, M. Leslie Fulcher, Scott H. Randell, Elizabeth J. Hudson
Publikováno v:
The Journal of Physiology. 590:545-562
Mucin secretion is an innate defence mechanism, which is noxiously upregulated in obstructive lung diseases (e.g. chronic obstructive pulmonary disease (COPD), cystic fibrosis and asthma). Mucin granule exocytosis is regulated by specific protein com
Autor:
Nancy L. Quinney, Jhuma Das, Martina Gentzsch, Nikolay V. Dokholyan, Deborah M. Cholon, Charles R. Esther, Scott H. Randell, Richard C. Boucher, M. Leslie Fulcher
Publikováno v:
Science translational medicine. 6(246)
Cystic Fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR). Newly developed “correctors” such as lumacaftor (VX-809) that improve CFTR maturation and trafficking and “potentiators” such as ivacaftor (VX-7
Autor:
Scott H. Randell, M. Leslie Fulcher
Publikováno v:
Methods in Molecular Biology ISBN: 9781627031240
Epithelial Cell Culture Protocols
Epithelial Cell Culture Protocols
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::becfe5069fac2dc3d4c49b1f4e4e9d92
https://doi.org/10.1007/978-1-62703-125-7
https://doi.org/10.1007/978-1-62703-125-7
Autor:
M Leslie, Fulcher, Scott H, Randell
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 945
Human airway epithelial (hAE) cell cultures are instrumental for studying basic and applied aspects of respiratory tract biology, disease, and therapy. When primary epithelial cells from the human nasal passages or tracheo-bronchial airways are grown
Autor:
M. Leslie Fulcher, Scott H. Randell
Publikováno v:
Methods in Molecular Biology ISBN: 9781627031240
Human airway epithelial (hAE) cell cultures are instrumental for studying basic and applied aspects of respiratory tract biology, disease, and therapy. When primary epithelial cells from the human nasal passages or tracheo-bronchial airways are grown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e4475a5fa8da47b1b655004f83f8f58
https://doi.org/10.1007/978-1-62703-125-7_8
https://doi.org/10.1007/978-1-62703-125-7_8