Zobrazeno 1 - 10
of 279
pro vyhledávání: '"M. Lerche"'
Autor:
Lauritz F. Brorsen, James S. McKenzie, Mette F. Tullin, Katja M. S. Bendtsen, Fernanda E. Pinto, Henrik E. Jensen, Merete Haedersdal, Zoltan Takats, Christian Janfelt, Catharina M. Lerche
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Cutaneous squamous cell carcinoma (SCC) is an increasingly prevalent global health concern. Current diagnostic and surgical methods are reliable, but they require considerable resources and do not provide metabolomic insight. Matrix-assisted
Externí odkaz:
https://doaj.org/article/e103aa582df742729eefc235cfdb89f2
Autor:
Ida M Heerfordt, Jeppe D Andersen, Peter A Philipsen, Linnea Langhans, Torben Tvedebrink, Grethe Schmidt, Thomas Poulsen, Catharina M Lerche, Niels Morling, Hans Christian Wulf
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0274413 (2022)
BackgroundCutaneous malignant melanoma (CMM) is curable if detected in its early stages. However, the clinical recognition of CMM is challenging. An American research group has shown promising results in detecting CMM based on RNA profiles sampled fr
Externí odkaz:
https://doaj.org/article/bb20199b67c0474b944d34f7217ac956
Autor:
Andreas Traberg, Fernanda E. Pinto, Anders C. N. Hansen, Merete Haedersdal, Catharina M. Lerche, Christian Janfelt
Publikováno v:
Pharmaceuticals, Vol 15, Iss 12, p 1583 (2022)
The aim of Quantitative mass spectrometry imaging (Q-MSI) is to provide distribution analysis and quantitation from one single mass-spectrometry-based experiment, and several quantitation methods have been devised for Q-MSI. Mimetic tissue models bas
Externí odkaz:
https://doaj.org/article/3913ca094aaf49079f8e48c2624f0b7f
Autor:
Kristoffer K. Hendel, Charlotte Bagger, Uffe H. Olesen, Christian Janfelt, Steen H. Hansen, Merete Haedersdal, Catharina M. Lerche
Publikováno v:
Drug Delivery, Vol 26, Iss 1, Pp 244-251 (2019)
Bleomycin exhibits antiproliferative effects desirable for use in dermato-oncology but topical use is limited by its 1415 Da molar mass. Ablative fractional laser (AFL)-assisted drug delivery has been shown to enhance drug uptake in skin. The aim of
Externí odkaz:
https://doaj.org/article/07e6d4529e5c4f52b5e2657aaca578eb
Autor:
Emily Wenande, Uffe H. Olesen, Malene R. Boesen, Daniel P. Persson, Catharina M. Lerche, Stefan Stürup, Bente Gammelgaard, Søren Husted, R. Rox Anderson, Merete Haedersdal
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 1877-1885 (2018)
Systemic chemotherapy with the anticancer agent cisplatin is approved for advanced non-melanoma skin cancer (NMSC), but topical treatment is limited by insufficient cutaneous penetration. We studied the impact of ablative fractional laser (AFL) expos
Externí odkaz:
https://doaj.org/article/7620effbbe9246fb84a5630fe01ca4d4
Autor:
CATHARINA M. LERCHE, FERNANDA E. PINTO, PETER A. PHILIPSEN, ELISABETH S. BECH, JETTE JAKOBSEN, MERETE HAEDERSDAL, HANS CHRISTIAN WULF
Publikováno v:
Lerche, C M, Pinto, F E, Philipsen, P A, Bech, E S, Jakobsen, J, Haedersdal, M & Wulf, H C 2022, ' High Oral Vitamin D 3 Intake Does Not Protect Against UVR-induced Squamous Cell Carcinoma in Mice ', Anticancer Research, vol. 42, no. 10, pp. 5083-5090 . https://doi.org/10.21873/anticanres.16017
Background/Aim: The effect of vitamin D on skin carcinogenesis is unclear. Vitamin D derivatives may protect against ultraviolet radiation (UVR)-induced DNA damage, immune suppression, and skin carcinogenesis. However, some epidemiological studies ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77eac3b4f441a587b2cd5f18bc6429f
https://doi.org/10.21873/anticanres.16017
https://doi.org/10.21873/anticanres.16017
Publikováno v:
Heerfordt, I M, Philipsen, P A, Lerche, C M & Wulf, H C 2023, ' Phototesting in erythropoietic protoporphyria trials : A systematic review ', Experimental Dermatology, vol. 32, no. 7, pp. 1042-1047 . https://doi.org/10.1111/exd.14809
Severe skin pain when exposed to long wave ultraviolet radiation or visible light is the main symptom of erythropoietic protoporphyria (EPP). Treatment options for EPP are inadequate and new treatments are needed but hampered by the lack of valid eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353b3d7bbb0e97bf9ce91a19247ebbb1
https://doi.org/10.1111/exd.14809
https://doi.org/10.1111/exd.14809
Autor:
Andrés M. Erlendsson, Lukas K. Rosenberg, Catharina M. Lerche, Katrine Togsverd‐Bo, Stine R. Wiegell, Katrine Karmisholt, Peter A. Philipsen, Anders C. N. Hansen, Christian Janfelt, Jon Holmes, Anthony Rossi, Merete Haedersdal
Publikováno v:
Lasers in Surgery and Medicine. 54:663-671
Patients with hypertrophic scars (HTS) risk reduced quality of life due to itching, pain, poor cosmesis, and restriction of movement. Despite good clinical efficacy, patients are often reluctant to undergo repeated needle injections due to pain or ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c601037dc980295a8968c11850a8686c
https://doi.org/10.1002/lsm.23529
https://doi.org/10.1002/lsm.23529
Publikováno v:
Heerfordt, I M, Lerche, C M, Philipsen, P A & Wulf, H C 2023, ' Experimental and approved treatments for skin photosensitivity in individuals with erythropoietic protoporphyria or X-linked protoporphyria : A systematic review ', Biomedicine and Pharmacotherapy, vol. 158, 114132 . https://doi.org/10.1016/j.biopha.2022.114132
Erythropoietic protoporphyria (EPP) and X-linked protoporphyria (XLP) are characterized by skin photosensitivity caused by accumulation of protoporphyrin IX. We aimed to review the clinical evidence of efficacy and safety of skin photosensitivity tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6f9fcc8f43a8edb307d6677797b2bc
https://curis.ku.dk/ws/files/332996205/1_s2.0_S0753332222015219_main.pdf
https://curis.ku.dk/ws/files/332996205/1_s2.0_S0753332222015219_main.pdf
Publikováno v:
Heerfordt, I M, Philipsen, P A, Lerche, C M & Wulf, H C 2023, ' Protection against visible light by dihydroxyacetone in erythropoietic protoporphyria ', Photodiagnosis and Photodynamic Therapy, vol. 41, 103302 . https://doi.org/10.1016/j.pdpdt.2023.103302
Background: Patients with erythropoietic protoporphyria (EPP) are hypersensitive to long wave ultraviolet (UVA) radiation and visible light and they experience severe skin pain by light exposure. The patients have very limited treatment options. Sunl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25892c8ebb85a1209ba882b4068e8fe
https://curis.ku.dk/portal/da/publications/protection-against-visible-light-by-dihydroxyacetone-in-erythropoietic-protoporphyria(884641dc-bee6-427a-99cc-757182d1c90f).html
https://curis.ku.dk/portal/da/publications/protection-against-visible-light-by-dihydroxyacetone-in-erythropoietic-protoporphyria(884641dc-bee6-427a-99cc-757182d1c90f).html