Zobrazeno 1 - 10
of 76
pro vyhledávání: '"M. Leick"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 4 (2023)
Increased immune cell infiltration into tumors is associated with improved patient survival and predicts response to immune therapies. Thus, identification of factors that determine the extent of immune infiltration is crucial, so that methods to int
Externí odkaz:
https://doaj.org/article/3095156331ae469a9c305300dd12551f
Autor:
Minyoung Kwak, Gulsun Erdag, Katie M. Leick, Stefan Bekiranov, Victor H. Engelhard, Craig L. Slingluff
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Immune cells in the tumor microenvironment have prognostic value. In preclinical models, recruitment and infiltration of these cells depends on immune cell homing (ICH) genes such as chemokines, cell adhesion molecules, and integr
Externí odkaz:
https://doaj.org/article/c15cf06be1c44250be629a5c814fea4a
Publikováno v:
OncoImmunology, Vol 8, Iss 12 (2019)
Background: We have identified, in melanomas, a set of genes encoding proteins that mediate mechanical barrier function in normal skin (barrier molecule genes, BMGs) and whose overexpression is associated with decreased immune signatures and shorter
Externí odkaz:
https://doaj.org/article/7cf98e6ff74946888f5c4f92f62188eb
Increased immune cell infiltration into tumors is associated with improved patient survival and predicts response to immune therapies. Thus, identification of factors that determine the extent of immune infiltration is crucial, so that methods to int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2bf5f0a8d7356ca65f021616f0599ae
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-506604
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-506604
Akademický článek
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Autor:
Ashley McCarthy, Pashtoon Murtaza Kasi, Kristen L Coleman, Ann Tomanek-Chalkley, Hannah R. Shrader, Carlos H. F. Chan, Maheen Rajput, Ann M. Miller, Austin G Kazarian, Katie M. Leick
Publikováno v:
Ann Surg Oncol
BACKGROUND: Disease burden in patients with peritoneal carcinomatosis (PC) is difficult to estimate. We evaluated whether peritoneal cell-free tumor DNA can be used as a measure of disease burden. METHODS: Malignant ascites or peritoneal lavage fluid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243293a5cf3ac5505da836a726192b3b
https://doi.org/10.1245/s10434-020-08832-9
https://doi.org/10.1245/s10434-020-08832-9
Autor:
Katie M. Leick, Stefan Bekiranov, Minyoung Kwak, Victor H. Engelhard, Craig L. Slingluff, Gulsun Erdag
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
BackgroundImmune cells in the tumor microenvironment have prognostic value. In preclinical models, recruitment and infiltration of these cells depends on immune cell homing (ICH) genes such as chemokines, cell adhesion molecules, and integrins. We hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be6b54e53a7c4d2a64637d8f203f7e5
https://doi.org/10.1186/s12967-021-03044-5
https://doi.org/10.1186/s12967-021-03044-5
Autor:
Victor H. Engelhard, Katie M. Leick, Mahmut Parlak, Anthony B. Rodriguez, Tarek Abbas, Craig L. Slingluff, Rebeka Eki, Kang-Ping Du, Mouadh Benamar, Robin S. Lindsay, Marit M. Melssen
Publikováno v:
Ann Surg
Objective To understand role of barrier molecules in melanomas. Background We have reported poor patient survival and low immune infiltration of melanomas that overexpress a set of genes that include filaggrin (FLG), dystonin (DST), junction plakoglo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164d4be473f39ddad6e9eb58a370dc6f
https://doi.org/10.1097/sla.0000000000003522
https://doi.org/10.1097/sla.0000000000003522
Autor:
Timothy L. McMurry, Tri Minh Le, Katie M. Leick, Yinin Hu, Bernadette J. Goudreau, Victor M. Zaydfudim
Publikováno v:
J Gastrointest Surg
BACKGROUND: The purpose of this study was to compare the long-term effectiveness of three lymphadenectomy strategies. We hypothesized that, compared to the traditional standard (D2) lymph node dissection strategy, the less aggressive modified standar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f80101a66e696b63d86b1e0d2469cb92
https://doi.org/10.1007/s11605-019-04393-9
https://doi.org/10.1007/s11605-019-04393-9
Publikováno v:
Surg Oncol Clin N Am
The incidence of melanoma continues to increase even as advances in immunotherapy have led to survival benefits in advanced stages. Vaccines are capable of inducing strong, antitumor immune responses with limited toxicity. Some vaccines have demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce76ba5d2824b2515b23922ab54c58b3
https://doi.org/10.1016/j.soc.2019.02.003
https://doi.org/10.1016/j.soc.2019.02.003