Zobrazeno 1 - 10
of 48
pro vyhledávání: '"M. Lakshmi Kuppusamy"'
Autor:
Anjali M. Prabhat, M. Lakshmi Kuppusamy, Shan K. Naidu, Sarath Meduru, Praneeth T. Reddy, Abishai Dominic, Mahmood Khan, Brian K. Rivera, Periannan Kuppusamy
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 5 (2018)
Myocardial infarction (MI), which occurs often due to acute ischemia followed by reflow, is associated with irreversible loss (death) of cardiomyocytes. If left untreated, MI will lead to progressive loss of viable cardiomyocytes, deterioration of ca
Externí odkaz:
https://doaj.org/article/03e7c0169b1c4e198268c6691330f82e
Autor:
Periannan Kuppusamy, Jesse M. Mast, Maciej M. Kmiec, M. Lakshmi Kuppusamy, John W Hinds, Tamás Kálai, Dan Tse, Balázs Bognár, Katherine Axelrod
Publikováno v:
Cell Biochemistry and Biophysics. 78:191-202
Pancreatic adenocarcinoma is an aggressive cancer with poor clinical prognosis and limited therapeutic options. There is a significant lack of effective, safe, and targeted therapies for successful treatment of pancreatic cancer. In this report, we d
Autor:
Huagang Hou, M. Lakshmi Kuppusamy, Periannan Kuppusamy, Anjali M. Prabhat, Jay C. Buckey, Aharon Blank, Eugene Demidenko, Sergey Petryakov, Maciej M. Kmiec, P.E. Schaner, Thomas M. Drews
Publikováno v:
Magnetic Resonance in Medicine. 81:2837-2840
This response is provided to address the questions raised in the letter to the editor by Henni et al. on our manuscript (Kmiec et al. Magn Reson Med 2019;81:781-794) describing the development of a new method for transcutaneous oxygen measurement in
Autor:
Lucas Citro, Shan Naidu, Fatemat Hassan, M Lakshmi Kuppusamy, Periannan Kuppusamy, Mark G Angelos, Mahmood Khan
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e116281 (2014)
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have recently been shown to express key cardiac proteins and improve in vivo cardiac function when administered following myocardial infarction. However, the efficacy of hiPSC-der
Externí odkaz:
https://doaj.org/article/d77d17997ac34e41bff003d6f30354cf
Autor:
Jesse M, Mast, John W, Hinds, Dan, Tse, Katherine, Axelrod, M Lakshmi, Kuppusamy, Maciej M, Kmiec, Balázs, Bognár, Tamás, Kálai, Periannan, Kuppusamy
Publikováno v:
Cell biochemistry and biophysics. 78(2)
Pancreatic adenocarcinoma is an aggressive cancer with poor clinical prognosis and limited therapeutic options. There is a significant lack of effective, safe, and targeted therapies for successful treatment of pancreatic cancer. In this report, we d
Autor:
Huagang Hou, Sergey Petryakov, Jay C. Buckey, Anjali M. Prabhat, Eugene Demidenko, Thomas M. Drews, Maciej M. Kmiec, M. Lakshmi Kuppusamy, Periannan Kuppusamy, Aharon Blank, P.E. Schaner
Purpose Transcutaneous oxygen tension (TcpO2 ) provides information about blood perfusion in the tissue immediately below the skin. These data are valuable in assessing wound healing problems, diagnosing peripheral vascular/arterial insufficiency, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c48a471095e1769274121b544879575e
https://europepmc.org/articles/PMC6289671/
https://europepmc.org/articles/PMC6289671/
Autor:
Tamás Kálai, Periannan Kuppusamy, Kálmán Hideg, Balázs Bognár, M. Lakshmi Kuppusamy, Anjali M. Prabhat
Publikováno v:
Cell biochemistry and biophysics. 77(1)
The synthesis and antiproliferative effect of a novel curcumin analog, 4,4’-disulfonyldiarylidenyl piperidone, are reported. The design of the molecule is based on the fusion of an antiproliferative segment, namely diarylidenyl piperidone (DAP), wi
Publikováno v:
Biomedical microdevices. 20(2)
Tissue oxygenation is a critical parameter in various pathophysiological situations including cardiovascular disease and cancer. Hypoxia can significantly influence the prognosis of solid malignancies and the efficacy of their treatment by radiation
Autor:
Periannan Kuppusamy, Christopher J Pelham, Sean D Smith, J. J. Gomm, Esha Madan, Louise J. Jones, Kevin Shee, Masaki Nagane, S. Kiparoidze, Yu Soon A. Park, Alan R. Fersht, M. Lakshmi Kuppusamy, Taylor M. Parker, Matthias R. Bauer, Alisha Dhiman, Kálmán Hideg, Laura A. Hansen, Matti Holmes, Karuppaiyah Selvendiran, Ana C. Cunha, Ana R. Tomás, Thomas R. Holmes, Rajan Gogna, Kranti Shaik
p53 is an important tumor-suppressor protein that is mutated in more than 50% of cancers. Strategies for restoring normal p53 function are complicated by the oncogenic properties of mutant p53 and have not met with clinical success. To counteract mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f63bd8c0a37cddfe4fbce8df87553ea2
https://europepmc.org/articles/PMC5868245/
https://europepmc.org/articles/PMC5868245/
Autor:
Richard J. Gumina, Uksha Saini, Periannan Kuppusamy, M. Lakshmi Kuppusamy, Konstantinos Dean Boudoulas, Brian Wolfe
Publikováno v:
Journal of Cellular Biochemistry. 114:2612-2623
Myocardial infarction is a leading cause of mortality and morbidity worldwide. Occlusion of a coronary artery produces ischemia and myocardial necrosis that leads to left ventricular (LV) remodeling, dysfunction, and heart failure. Stem cell therapy