Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

Autor: Stephan Zipfel, Hidetoshi Inoko, K. Fischer, Laramie E. Duncan, Jochen Seitz, Lars Klareskog, Ina Giegling, Grant W. Montgomery, Manuel Föcker, Colin A. Johnson, Agnieszka Słopień, Dong Li, M. C. T. Slof-Op 't Landt, Thomas Werge, Janiece E. DeSocio, Stefan Ehrlich, Joseph M. Boden, Patrick F. Sullivan, M. La Via, Bochao Danae Lin, Andreas Karwautz, Ilka Boehm, Lenka Foretová, Stephen W. Scherer, Anders Juréus, Jolanta Lissowska, Janne Tidselbak Larsen, Antonio Julià, A. Metspalu, Roger A.H. Adan, George Dedoussis, Stefan Herms, Franziska Ritschel, Martin A. Kennedy, Vesna Boraska Perica, S.D. Gordon, Johanna Giuranna, Janet Treasure, Youl-Ri Kim, Joanna Hauser, Manfred M. Fichter, P.E. Slagboom, Wade H. Berrettini, Kirstin L. Purves, Fernando Fernández-Aranda, Eleftheria Zeggini, Nadia Micali, Anne Farmer, Beata Swiatkowska, Tracey D. Wade, Claudette Boni, Fragiskos Gonidakis, Ioanna Ntalla, Johannes Pantel, Raquel Rabionet, Pierre J. Magistretti, Johannes Hebebrand, Mario Maj, Sietske G. Helder, Roland Burghardt, Sarah E. Medland, Maurizio Clementi, John F. Pearson, Gerd Wagner, V. Janout, Susana Jiménez-Murcia, Mikael Landén, Samuli Ripatti, Sandro Sorbi, Martien J H Kas, Leonid Padyukov, Zeynep Yilmaz, Kelly L. Klump, Paul Lichtenstein, Shuyang Yao, Dan Rujescu, James J. Crowley, Valdo Ricca, Palmiero Monteleone, Steve Crawford, Sébastien Guillaume, Liselotte Petersen, Yiran Guo, Stephan Ripke, Beate Herpertz-Dahlmann, Marie Navratilova, S. Gallinger, Anjali K. Henders, Cynthia M. Bulik, Wolfgang Herzog, Alfonso Tortorella, Christian Dina, Garret D. Stuber, A. A. van Elburg, Manuel Mattheisen, Harry Brandt, Hunna J. Watson, Alessandro Rotondo, Roel A. Ophoff, Artemis Tsitsika, Nicholas G. Martin, Sara Marsal, Konstantinos Tziouvas, Ken B. Hanscombe, Alessio Maria Monteleone, Ted Reichborn-Kjennerud, Anu Raevuori, Lars Alfredsson, E. F. van Furth, Hartmut Imgart, Esther Walton, Julie K. O'Toole, Katharina Buehren, Unna N. Danner, Hana Papezova, Katherine M. Kirk, Deborah Kaminská, Lisa R. Lilenfeld, Aarno Palotie, Paola Giusti-Rodríguez, Jennifer Jordan, Gun Peggy Knudsen, L. Slachtova, Ole A. Andreassen, Monica Gratacos Mayora, Elisabeth Widen, Benedetta Nacmias, Nicholas J. Schork, Monika Dmitrzak-Weglarz, Jurjen J. Luykx, André Scherag, Christopher Hübel, Laura M. Thornton, Marion Roberts, Angela Favaro, Catherine M. Olsen, Jaakko Kaprio, S Le Hellard, Federica Tozzi, Monica Forzan, Claes Norring, Leila Karhunen, Karin Egberts, Dalila Pinto, Geòrgia Escaramís, Nicolas Ramoz, Robert D. Levitan, Laura M. Huckins, Ulrike Schmidt, Gerome Breen, Kirsty Kiezebrink, Andreas J. Forstner, Scott J. Crow, Ingrid Meulenbelt, Dimitris Dikeos, Sven Cichon, Daniela Degortes, L. J. Horwood, Tetsuya Ando, Jonathan R. I. Coleman, Stephanie Zerwas, Katherine A. Halmi, Helena Gaspar, Andrew W. Bergen, Elena Tenconi, Katrin Männik, Christopher S. Franklin, Anna Keski-Rahkonen, Sara McDevitt, Marta Tyszkiewicz-Nwafor, Jakob Grove, Philip Gorwood, Christian R. Marshall, Preben Bo Mortensen, Melissa A. Munn-Chernoff, Hakon Hakonarson, Roger D. Cone, Allan S. Kaplan, Paolo Santonastaso, James I. Hudson, M. de Zwaan, Xavier Estivill, James E. Mitchell, Danielle M. Dick, Jessica H. Baker, Peter McGuffin, Walter H. Kaye, Michael Strober, D. B. Woodside, Oliver S. P. Davis, Karen S. Mitchell, David C. Whiteman, Julien Bryois, Nancy L. Pedersen, Philippe Courtet, Virpi M. Leppä, Konstantinos Hatzikotoulas, T Esko, Matteo Cassina, Andreas Birgegård, Anke Hinney, Richard Parker, James L. Kennedy, Elisa Docampo, Ioanna Tachmazidou, Jin P. Szatkiewicz, Alexandra Schosser, Filip Rybakowski, Morten Mattingsdal, Gursharan Kalsi

Publikováno v: Yearbook of Paediatric Endocrinology.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39297353db610b9b7ea56344b212d187
https://doi.org/10.1530/ey.17.15.18

Evidence for the role of EPHX2 gene variants in anorexia nervosa

Autor: Nicholas J. Schork, Vikas Bansal, D. B. Woodside, Erin N. Smith, K. Plotnicov, Katherine A. Halmi, Sathanur R. Srinivasan, Pierre J. Magistretti, Cynthia M. Bulik, Janet Treasure, Thomas Phillips, Manfred M. Fichter, Gerald S. Berenson, A. A. Scott-Van Zeeland, L. Galvez, Nathan E. Wineinger, M. La Via, Phillip H. Pham, Harry Brandt, Pamela K. Keel, Eric J. Topol, Vikas Duvvuri, Lisa R. Lilenfeld, Guangfa Zhang, Alessandro Rotondo, Scott J. Crow, Kelly L. Klump, Andrew W. Bergen, Sarah S. Murray, Wade H. Berrettini, Andrew R. Carson, Sybil L. Crawford, Burcu F. Darst, S. Levy, Pei-an Betty Shih, Craig Johnson, Ondrej Libiger, Ali Torkamani, Michael Strober, Cinnamon S. Bloss, Wai Chen, Rebecca L. Tisch, Nikki Villarasa, Walter H. Kaye, Allan S. Kaplan, James E. Mitchell, Ryan Tewhey

Publikováno v: Molecular Psychiatry
Molecular psychiatry, vol 19, iss 6

Anorexia nervosa (AN) and related eating disorders are complex, multifactorial neuropsychiatric conditions with likely rare and common genetic and environmental determinants. To identify genetic variants associated with AN, we pursued a series of seq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3fd6312d159b3c240cba93e4dfbf5fd
https://pubmed.ncbi.nlm.nih.gov/23999524

Long-term exercise patterns and immune function in healthy older women. A report of preliminary findings

Autor: S H, Gueldner, L W, Poon, M, La Via, G, Virella, Y, Michel, M H, Bramlett, C A, Noble, E, Paulling

Publikováno v: Mechanisms of ageing and development. 93(1-3)

The purpose of this study was to examine the relationship between active versus inactive lifestyle and immunocompetence in older women. A sample of 46 independently dwelling, ambulatory and mentally alert women 60-98 years was examined, 25 who rated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::57446076f9ae76da9d5e4c4f8dfe1769
https://pubmed.ncbi.nlm.nih.gov/9089585

A study of immunoglobulin structure. I. The fingerprinting of aminoethylated Bence-Jones proteins

Autor: M. La Via, C. Baglioni, V. Ventruto

Publikováno v: Biochimica et biophysica acta. 111(2)

A method for the structural analysis of Bence-Jones proteins has been devised. These proteins are isolated from the urine of patients with multiple myeloma by ammonium sulphate fractionation. The Bence-Jones proteins are reduced with mercapto-ethanol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d519ab38b8789a816bffa8bc8f18606
https://pubmed.ncbi.nlm.nih.gov/5879480

Associations between dimensions of anorexia nervosa and obsessive-compulsive disorder: An examination of personality and psychological factors in patients with anorexia nervosa.

Autor: Levinson CA; Department of Psychological and Brain Sciences, University of Louisville, Louisville, Kentucky., Zerwas SC; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Brosof LC; Department of Psychological and Brain Sciences, University of Louisville, Louisville, Kentucky., Thornton LM; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Strober M; UCLA Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California., Pivarunas B; Department of Psychology, Colorado State University, Fort Collins, Colorado., Crowley JJ; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Yilmaz Z; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Berrettini WH; Center of Neurobiology and Behavior, University of Pennsylvania, Philadelphia, Pennsylvania., Brandt H; Center for Eating Disorders, Sheppard Pratt Health System, Towson, Maryland., Crawford S; Center for Eating Disorders, Sheppard Pratt Health System, Towson, Maryland., Fichter MM; Klinik Roseneck, Hospital for Behavioral Medicine and University of Munich (LMU), Munich, Germany., Halmi KA; Weill Cornell Medical College, New York Presbyterian Hospital - Westchester Division, White Plains, New York., Johnson C; Eating Recovery Center, Denver, Colorado., Kaplan AS; Program for Eating Disorders, Toronto General Hospital and University Health Network, University of Toronto, Toronto, ON, Canada., La Via M; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Mitchell J; Department of Clinical Neuroscience and Neuropsychiatric Research Institute, University of North Dakota School of Medicine and Health Sciences, Fargo, North Dakota., Rotondo A; Department of Psychiatry, Pharmacology and Biotechnologies, University of Pisa, Pisa, Italy., Woodside DB; Department of Psychiatry, University of Toronto, Toronto, ON, Canada., Kaye WH; University of San Diego, San Diego, California., Bulik CM; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

Publikováno v: European eating disorders review : the journal of the Eating Disorders Association [Eur Eat Disord Rev] 2019 Mar; Vol. 27 (2), pp. 161-172. Date of Electronic Publication: 2018 Aug 22.