Výsledky vyhledávání - "M. L. W. Kluppel"

Amiodarone effects on membrane organization evaluated by fluorescence polarization

Autor: Romeu A. Videira, Vítor M.C. Madeira, M. L. W. Kluppel, M.C. Antunes-Madeira

Publikováno v: International Journal of Cardiology. 48:211-218

The effects of amiodarone (0-100 microM) on the physical state of synthetic and native membranes were investigated by fluorescence polarization of 1,6-diphenyl-1,3,5-hexatriene (DPH), probing the bilayer core, and of its anionic propionic acid deriva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c9965f9651313e3151e4a8be236d13
https://doi.org/10.1016/0167-5273(94)02247-g

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Caracterização de miopatias mitocondriais através da avaliação das atividades enzimáticas envolvidas no metabolismo energético

Autor: Lineu Cesar Werneck, Annibal P. Campello, M. L. W. Kluppel, Fábio Cesar Pedroso

Publikováno v: Arquivos de Neuro-Psiquiatria, Volume: 55, Issue: 2, Pages: 249-257, Published: JUN 1997
Arquivos de Neuro-Psiquiatria v.55 n.2 1997
Arquivos de neuro-psiquiatria
Academia Brasileira de Neurologia
instacron:ABNEURO

Foi determinada a atividade das enzimas NADH desidiogenase, NADH citocromo e redutase, succinato desidiogenase, succinato citocromo e redutase, citocromo e oxidase e citrato sintase em mitocôndrias de músculo esquelético humano normal e doente (su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e769af60735e9bd9310b5d7b8263e7
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1997000200013&lng=en&tlng=en

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Alterations induced by citrinin in cultured kidney cells

Autor: Dorly de Freitas Buchi, Annibal P. Campello, Maria Benigna M. Oliveira, M. L. W. Kluppel, Generoso M. Chagas

Publikováno v: Cell structure and function. 19(2)

The cytotoxicity of citrinin was evaluated in an established cell line of baby hamster kidney cells. The primary effect of the mycotoxin was on the adherence of the cells to the culture bottles. Microscopic evaluation of morphological alterations ind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8518453f0e75b2b8aff97a8ff75203d
https://pubmed.ncbi.nlm.nih.gov/7923397

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Methotrexate: studies on cellular metabolism. IV. Effect on the mitochondrial oxidation of cytosolic-reducing equivalents in HeLa cells

Autor: M B Oliveria, M T Bastos, M. L. W. Kluppel, Annibal P. Campello

Publikováno v: Cell biochemistry and function. 8(4)

The effect of methotrexate (MTX) on the mitochondrial oxidation of cytosolic-reducing equivalents in HeLa cells was studied. MTX inhibited (100 per cent) malate dehydrogenase activity, but no effect was observed on that of GOT. MTX (0.5 mM) inhibited

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b86093871cf7e1d3d70de94339fd6d65
https://pubmed.ncbi.nlm.nih.gov/2272117

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Methotrexate: studies on cellular metabolism. II--Effects on mitochondrial oxidative metabolism and ion transport

Autor: Nair Yamamoto, M. L. W. Kluppel, Luiz Carlos Vieira Lopes, Annibal P. Campello

Publikováno v: Cell biochemistry and function. 7(2)

Effects of methotrexate (MTX) on mitochondrial oxidative metabolism and ion transport were studied. MTX decreases the membrane potential (delta psi) upon energization of the mitochondrial membrane by NAD+-linked substrates and decreases the amplitude

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4043a42c829b739971b669a52db6dd8
https://pubmed.ncbi.nlm.nih.gov/2766470

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Biochemical aspects of the mechanism of action of antiarrhythmic drugs on mitochondria. VII. Effect on energy-linked reactions and on membrane potential

Autor: Hélcio Resende Borba, M. L. W. Kluppel, Annibal P. Campello, Luiz Carlos Vieira Lopes, O. Silveira

Publikováno v: Cell biochemistry and function. 4(4)

Effects of the antiarrhythmic drugs (propranolol, perhexiline maleate, lidoflazine and iproveratril) on energy-linked reactions and on membrane potential were studied. Propranolol, perhexiline maleate and lidoflazine inhibit the ATPase activity of un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f73fade0b9e9550ec5b3aaa544fc6e5a
https://pubmed.ncbi.nlm.nih.gov/2878737

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Possible mechanism of action of perhexiline maleate on heart mitochondria

Autor: M. L. W. Kluppel, Annibal P. Campello, L.C Vieira Lopes, O. Silveira

Publikováno v: Biochemical pharmacology. 25(21)

Oxidative phosphorylation and oxidation of NAD+-linked substrates by rat heart mitochondria were depressed by 6.75 × 10−5 M perhexiline maleate (PM), while the succinate oxidation was increased to 320 per cent activity. The drug had no effect on m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd9f68b59510593a0eb16ec2a7997eaa
https://pubmed.ncbi.nlm.nih.gov/999725

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Akademický článek

Mitochondrial Bioenergetics after Nine-Day Treatment Regimen with Benzonidazole in Rats.

Autor: Rendon, D. A.¹ darendon@unalmed.edu.co

Publikováno v: International Journal of Toxicology (Taylor & Francis). Nov2007, Vol. 26 Issue 6, p571-575. 5p. 2 Charts, 3 Graphs.

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