Zobrazeno 1 - 10
of 11
pro vyhledávání: '"M. L. Tod"'
Publikováno v:
American Journal of Physiology-Cell Physiology. 268:C259-C270
Cytochrome P-450 (P-450) is a NADPH-requiring and O2-dependent monooxygenase system. It is present in lung and has been postulated to act as an O2 sensor in hypoxic pulmonary vasoconstriction. To determine whether P-450 is involved in the regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af647aebf8c2fc44569d8771ad5501d
https://doi.org/10.1152/ajpcell.1995.268.1.c259
https://doi.org/10.1152/ajpcell.1995.268.1.c259
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 259:H281-H289
The effects of hypoxia on resting and K-stimulated tension were tested on small rings of rat pulmonary and mesenteric resistance arteries (SPA and SMA, respectively) and on the large branches of the main pulmonary artery (LPA). Reduction of PO2 from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8a9d5e309f467b881af106d3cea1878
https://doi.org/10.1152/ajpheart.1990.259.2.h281
https://doi.org/10.1152/ajpheart.1990.259.2.h281
Autor:
L. J. Rubin, M. L. Tod
Publikováno v:
Journal of Applied Physiology. 73:2717-2719
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb8cbe100bc6aded6702e02e05050e09
https://doi.org/10.1152/jappl.1992.73.6.2717
https://doi.org/10.1152/jappl.1992.73.6.2717
Publikováno v:
Canadian journal of physiology and pharmacology. 76(7-8)
Previous studies have shown that the attenuated hypoxic pulmonary vasoconstriction (HPV) of young newborn lamb lungs was enhanced by cyclooxygenase inhibition. We sought to determine whether this reflected greater synthesis of and (or) responsiveness
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1ffb3565cea8d451dcb36ce37e8a6dfc
https://pubmed.ncbi.nlm.nih.gov/10030457
https://pubmed.ncbi.nlm.nih.gov/10030457
Publikováno v:
Molecular pharmacology. 46(4)
2-Methyl-2-nitrosopropane (MNP) has long been known to undergo photochemical and thermal decomposition, generating di-tert-butyl nitroxide, in organic solvent. The present study was undertaken to demonstrate that MNP can be used as a caged-nitric oxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3746d087d49b53394164a7fa14dfe7f9
https://pubmed.ncbi.nlm.nih.gov/7969050
https://pubmed.ncbi.nlm.nih.gov/7969050
Autor:
M. L. Tod, John B. Gordon
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 75(1)
To determine whether endothelium-derived nitic oxide (EDNO), like dilator prostaglandins, attenuates pulmonary vasomotor tone more in younger than in older newborns, we examined the effects of a nitric oxide synthase inhibitor, N omega-nitro-L-argini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d383842b928a533cc31cd4c1c2b5641
https://pubmed.ncbi.nlm.nih.gov/8376304
https://pubmed.ncbi.nlm.nih.gov/8376304
Autor:
J. T. Sylvester, M. L. Tod
Publikováno v:
Journal of Applied Physiology. 66:79-87
The distribution of pulmonary vascular resistance (PVR) with respect to compliance was determined using vascular occlusion in isolated lungs from lambs at five ages, from 2 wk before birth to 1 mo of age. The major change in PVR occurred in the press
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2968752c7c38358e2acb5b82ff929e
https://doi.org/10.1152/jappl.1989.66.1.79
https://doi.org/10.1152/jappl.1989.66.1.79
Publikováno v:
Journal of Applied Physiology. 58:710-716
Arachidonic acid causes dose-dependent increases in pulmonary vascular resistance in perinatal lambs. The specific metabolites that produce this effect are not known; however, a role for thromboxanes (TX's), potent constrictors of vascular smooth mus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c3c4467341d6e2e7160117aa33debc
https://doi.org/10.1152/jappl.1985.58.3.710
https://doi.org/10.1152/jappl.1985.58.3.710
Publikováno v:
Journal of applied physiology: respiratory, environmental and exercise physiology. 57(4)
Dilator prostaglandins are released from the perinatal lung in response to ventilation and also may be involved in the pressor response to hypoxia. However, arachidonic acid, precursor of bisenoic prostaglandins, causes pulmonary vasoconstriction whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a53ce8a93ef18d1183d63c147288af
https://pubmed.ncbi.nlm.nih.gov/6438033
https://pubmed.ncbi.nlm.nih.gov/6438033
Publikováno v:
Pediatric research. 23(6)
Although smooth muscle is abundant in the pulmonary vessels of young animals at birth, it is not clear if these vessels respond more vigorously to hypoxia than the less muscular vessels of older neonates. To determine the effect of age on the pulmona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de0e3df04e4777cc9debca9778fd4643
https://pubmed.ncbi.nlm.nih.gov/3393389
https://pubmed.ncbi.nlm.nih.gov/3393389