Zobrazeno 1 - 10
of 20
pro vyhledávání: '"M. L. Taha"'
Autor:
Hassan B. Lazrek, M. L. Taha
Publikováno v:
Bulletin des Sociétés Chimiques Belges. 104:591-594
The 6-benzylaminopurine 1 has been alkylated with (2-acetoxyethoxy)methylbromide 3, using trimethylsilylation and phase transfer catalysis procedures. The influence of the base, the solvent and the catalyst were studied. When the solid-liquid phase t
Autor:
M. L. Taha, Hassan B. Lazrek
Publikováno v:
Bulletin des Sociétés Chimiques Belges. 104:647-652
The chemical synthesis of some 4-substituted 1-(4-hydroxybutyl)pyrazolo[3,4-d]pyrimidines was described. Using solid-liquid phase transfer catalysis, the 4-alkylthio-1-(4-acetoxybutyl)pyrazolo[3,4-d]pyrimidines 3a-c were regioselectively prepared in
Publikováno v:
Bulletin des Sociétés Chimiques Belges. 105:279-285
A number of 4-substituted pyrazolo[3,4-d]pyrimidines 1a-f has been coupled with (2-acetoxyethoxy)methylbromide 2, using liquid-liquid and solid-liquid phase transfer catalysis. The influence of the solvent and catalyst has been studied. The N1 isomer
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 21:165-176
The chemical synthesis of some acyclic alpha-(1H-pyrazolo[3,4-d]pyrimidin-4-yl)thioalkylamide nucleosides (10-12)a-c is described. The treatment of IH-pyrazolo[3,4-d]pyrimidin-4-thione 1 with compounds 2a-c gave, regioselectively, ethyl alpha-(1H-pyr
Autor:
Christophe Pannecouque, Jean Louis Imbach, O. Moukha‐Chafiq, M. L. Taha, J. L. Barascut, Hassan B. Lazrek, E. De Clercq, Myriam Witvrouw
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 20:1797-1810
The chemical synthesis of some 4-substituted 1-[1-(2-hydroxyethoxy)-methyl-1,2.3-triazol-(4 and 5)-ylmethyl]-1-H-pyrazolo[3,4-d]pyrimidines 12a,b, 13a,b and 14-23 as acyclic nucleosides is described. Treatment of (2-acetoxyethoxy)methylbromide with s
Autor:
Jean-Jacques Vasseur, M. L. Taha, Hassan B. Lazrek, Christophe Pannecouque, Myriam Witvrouw, De Clercq E, Moukha-Hafiq O
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 20:1811-1821
The synthesis of 1-[1-(4-hydroxybutyl)-1,2,3-triazol-(4 and 5)-ylmethyl]-1H-pyrazolo[3,4-d]pyrimidines 11a,b, 12a,b and 13-17 as carboacyclic nucleosides is described. The compounds 8a,b were condensed, separately, with compound 7 via 1,3-dipolar cyc
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 20:955-958
The synthesis of some acyclic alpha-(pyrazolo[3,4-d]pyrimidin-4-ylthio)alkylamide nucleosides is described.
Autor:
Hassan B. Lazrek, M. L. Taha
Publikováno v:
ChemInform. 27
The 6-benzylaminopurine 1 has been alkylated with (2-acetoxyethoxy)methylbromide 3, using trimethylsilylation and phase transfer catalysis procedures. The influence of the base, the solvent and the catalyst were studied. When the solid-liquid phase t
Autor:
Hassan B. Lazrek, M. L. Taha
Publikováno v:
ChemInform. 27
The chemical synthesis of some 4-substituted 1-(4-hydroxybutyl)pyrazolo[3,4-d]pyrimidines was described. Using solid-liquid phase transfer catalysis, the 4-alkylthio-1-(4-acetoxybutyl)pyrazolo[3,4-d]pyrimidines 3a-c were regioselectively prepared in
Publikováno v:
ChemInform. 27
A number of 4-substituted pyrazolo[3,4-d]pyrimidines 1a-f has been coupled with (2-acetoxyethoxy)methylbromide 2, using liquid-liquid and solid-liquid phase transfer catalysis. The influence of the solvent and catalyst has been studied. The N1 isomer