Zobrazeno 1 - 10
of 130
pro vyhledávání: '"M. L. Roumestant"'
Publikováno v:
Bulletin des Sociétés Chimiques Belges. 103:1-8
In this report the importance of heterocycles in amino acid and peptide chemistry is pointed out. Neuroexcitatory amino acids, kainic acid, quisqualic acid, of which new syntheses are given, are representative examples of the role of the heterocycle
Publikováno v:
Tetrahedron: Asymmetry. 15:851-858
Several new 4-substituted glutamic acid derivatives are described: 4-phosphinomethyl glutamic acid derivatives were prepared starting from (2 S )- N -Boc- tert -butyl-4-methylene glutamate. The 4-carboxymethyl and 4-aminomethyl glutamic acid derivati
Autor:
Jean-Pierre Lavergne, M. L. Roumestant, Abdelrhani Elachqar, A. Ben-Tama, El Mestafa El Hadrami, A. El Hallaoui, Ph. Viallefont
Publikováno v:
Amino Acids. 24:423-426
α-Heterocyclic α-aminoesters were obtained in good yields by reaction of a glycine cation equivalent and different heterocyclic nucleophiles; diastereoselectivity using a carbohydrate (galactopyranose) as N-protecting group was modest.
Publikováno v:
Tetrahedron: Asymmetry. 14:1123-1126
A short four-step synthesis of (2S,3R)- and (2S,3S)-3-methyl glutamic acids is reported; the (2S,3R) isomer presented a significant inhibitory effect on glutamate transport.
Publikováno v:
Synthesis. :2165-2168
The Michael addition of secondary cyclic aromatic and nonaromatic amines to methyl 2-{[(tert-butoxycarbonyl)amino]methyl)acrylate afforded substituted β 2 -amino esters in good to excellent yields.
Autor:
Jean Martinez, M. L. Roumestant, Valérie Rolland, Mohamad Tabcheh, Marc Rolland, Tarek Kassem, Johny Wehbe
Publikováno v:
Org. Biomol. Chem.. 1:1938-1942
A short asymmetric synthesis of optically pure beta-substituted beta-hydroxy aspartates is described. The key step is an aldol reaction between a glycine enolate derived from an oxazinone intermediate used as chiral auxiliary and various alpha-keto e
Publikováno v:
Synthetic Communications. 32:181-187
Reaction of urethane N-carboxyanhydrides with unprotected amino sugars was the key step in the synthesis of new trimodular surfactants.
Autor:
Marc Rolland, Valérie Rolland-Fulcrand, Jean Martinez, M. L. Roumestant, Jonhy Wehbe, Tarek Kassem
Publikováno v:
Tetrahedron: Asymmetry. 12:2657-2661
A short four-step synthesis of (3R,4R,5R)-4-hydroxyisoleucine lactone with total control of stereochemistry is reported, the key intermediate being the didehydroamino acid derivative arising from an aldol dehydration reaction between a glycine anion
Publikováno v:
Preparative Biochemistry and Biotechnology. 31:71-80
The chemoenzymatic synthesis of new surfactants is reported; they were prepared from unprotected carbohydrates, amino acids, and fatty acids. This study pointed out the factors that govern the possibility to enzymatically bind the carbohydrate to the
Autor:
L. Lecointe, M. L. Roumestant, Valérie Rolland, Philippe Viallefont, J. Martine, L. Pappalardo
Publikováno v:
The Journal of Peptide Research. 55:300-307
The synthesis of enantiomerically pure azatyrosine, tribromophenylalanine and trichlorophenylalanine is described, using two methods, diastereoselective alkylation and (or) diastereoselective protonation of chiral enolates.