Zobrazeno 1 - 10
of 58
pro vyhledávání: '"M. L. Paine"'
Autor:
Geoffroy Andrieux, Tonmoy Das, Michaela Griffin, Jakob Straehle, Simon M. L. Paine, Jürgen Beck, Melanie Boerries, Dieter H. Heiland, Stuart J. Smith, Ruman Rahman, Sajib Chakraborty
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-34 (2023)
Abstract Background Spatiotemporal heterogeneity originating from genomic and transcriptional variation was found to contribute to subtype switching in isocitrate dehydrogenase-1 wild-type glioblastoma (GBM) prior to and upon recurrence. Fluorescence
Externí odkaz:
https://doaj.org/article/ddc7f16df4c243c3bdd8102718b49299
Autor:
Wenshi He, Max K. Edney, Simon M. L. Paine, Rian L. Griffiths, David J. Scurr, Ruman Rahman, Dong-Hyun Kim
Publikováno v:
Analytical Chemistry. 95:5994-6001
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d716f56da9bb2f4ff464762fcec067b
https://doi.org/10.1021/acs.analchem.2c05807
https://doi.org/10.1021/acs.analchem.2c05807
Autor:
Stuart D. Paine, M. L. Paine
In 1933 Antarctica was essentially unexplored. Admiral Richard Byrd launched his Second Expedition to chart the southernmost continent, primarily relying on the muscle power of dog teams and their drivers who skied or ran beside the loaded sledges as
Autor:
Christopher D. Bennett, Sarah E. Kohe, Simrandip K. Gill, Nigel P. Davies, Martin Wilson, Lisa C. D. Storer, Timothy Ritzmann, Simon M. L. Paine, Ian S. Scott, Ina Nicklaus-Wollenteit, Daniel A. Tennant, Richard G. Grundy, Andrew C. Peet
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Paediatric brain tumors are becoming well characterized due to large genomic and epigenomic studies. Metabolomics is a powerful analytical approach aiding in the characterization of tumors. This study shows that common cerebellar tumors have
Externí odkaz:
https://doaj.org/article/a7d2970fe73a49548b25fcf0b28229c9
Publikováno v:
The Cerebellum.
Cerebellar neurodegeneration is a classical feature of ataxia telangiectasia (A-T), an autosomal recessive condition caused by loss-of-function mutation of the ATM gene, a gene with multiple regulatory functions. The increased vulnerability of cerebe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b241bb4bcc8ae1f71873adb6328f631d
https://doi.org/10.1007/s12311-023-01560-2
https://doi.org/10.1007/s12311-023-01560-2
Autor:
Timothy A Ritzmann, Rebecca J Chapman, John-Paul Kilday, Nicola Thorp, Piergiorgio Modena, Robert A Dineen, Donald Macarthur, Conor Mallucci, Timothy Jaspan, Kristian W Pajtler, Marzia Giagnacovo, Thomas S Jacques, Simon M L Paine, David W Ellison, Eric Bouffet, Richard G Grundy
Publikováno v:
Neuro Oncol
Background SIOP Ependymoma I was a non-randomised trial assessing event free and overall survival (EFS/OS) of non-metastatic intracranial ependymoma in children aged 3–21 years treated with a staged management strategy. A further aim was to assess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ea4d0e85dbb3c7fae100da09620ade
https://doi.org/10.1093/neuonc/noac012
https://doi.org/10.1093/neuonc/noac012
Autor:
Rebecca J Chapman, David R Ghasemi, Felipe Andreiuolo, Valentina Zschernack, Arnault Tauziede Espariat, Francesca R Buttarelli, Felice Giangaspero, Jacques Grill, Christine Haberler, Simon M L Paine, Ian Scott, Thomas S Jacques, Martin Sill, Stefan Pfister, John-Paul Kilday, Pierre Leblond, Maura Massimino, Hendrik Witt, Piergiorgio Modena, Pascale Varlet, Torsten Pietsch, Richard G Grundy, Kristian W Pajtler, Timothy A Ritzmann
Publikováno v:
Neuro-Oncology.
BackgroundAccurate identification of brain tumour molecular subgroups is increasingly important. We aimed to establish the most accurate and reproducible ependymoma subgroup biomarker detection techniques, across 147 cases from International Society
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7fcb91485dd9ae3d8b79f04b628c72b
https://doi.org/10.1093/neuonc/noad055
https://doi.org/10.1093/neuonc/noad055
Autor:
Dorothee P. Auer, Rocio Figueroa, Mark Bishton, Christopher P. Fox, Vishakha Sovani, Nicolas Martinez-Calle, Eleanor James, Furqaan A Kaji, Paul Byrne, Eric M Bessell, Joanne Adlington, Stuart Smith, Matthew J. Grainge, Simon M. L. Paine, M. O'Donoghue
Publikováno v:
British Journal of Haematology. 195:561-570
Observational studies with long-term follow-up of patients with primary central nervous system lymphoma (PCNSL) are scarce. Patient data over a period of four decades were retrospectively analysed from databases at Not-tingham University Hospitals Tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f94bc589d8455772bf3902ec84989685
https://doi.org/10.1111/bjh.17747
https://doi.org/10.1111/bjh.17747
Autor:
Amy R Fairchild, Jessica C Pickles, François Guillemot, Martin Tisdall, Darren Hargrave, Dale Moulding, Simon M. L. Paine, Fatma Scerif, SA Yasin, Thomas S. Jacques, Simon R. Picker, Aimee Avery, Thomas J Stone, Yao-Feng Li, J. Helen Cross, Alex Virasami, William Harkness
Publikováno v:
Neuropathology and Applied Neurobiology. 47:781-795
Aims We understand little of the pathogenesis of developmental cortical lesions, because we understand little of the diversity of the cell types that contribute to the diseases or how those cells interact. We tested the hypothesis that cellular diver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79af7881397542e0975e33b0d02f6ebd
https://doi.org/10.1111/nan.12715
https://doi.org/10.1111/nan.12715
Autor:
Dorothee P. Auer, Manish Prasad, Gabriel Chow, William P Whitehouse, Stefan Pszczolkowski, Caroline Blanchard, Simon M. L. Paine, Robert A. Dineen
Publikováno v:
AJNR Am J Neuroradiol
BACKGROUND AND PURPOSE: SWI hypointense cerebral lesions have been reported in adults with the inherited cerebellar neurodegenerative disorder ataxia telangiectasia. This study aims to establish the prevalence, age-dependency, and spatial distributio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9f5f8bd653e3fa53602c0486e882b6
https://doi.org/10.3174/ajnr.a7107
https://doi.org/10.3174/ajnr.a7107