Zobrazeno 1 - 5
of 5
pro vyhledávání: '"M. L. M. Mannesse"'
Autor:
H. M. Verheij, Henri A. M. Pepermans, M. L. M. Mannesse, A. Groenewegen, M. R. Egmond, Cornelis W. Hilbers, Jeanine J. Prompers, B. Van Noorloos
Publikováno v:
Biochemistry, 38(19), 5982-5994. American Chemical Society
The backbone dynamics of Fusarium solani pisi cutinase in complex with a phosphonate inhibitor has been studied by a variety of nuclear magnetic resonance experiments to probe internal motions on different time scales. The results have been compared
Autor:
M. L. M. Mannesse, Hubertus M. Verheij, G.H. de Haas, Maarten R. Egmond, Christian Cambillau, Sonia Longhi, E. Knoops-Mouthuy
Publikováno v:
Protein Science. 6:275-286
Cutinase from Fusarium solani is a lipolytic enzyme that hydrolyses triglycerides efficiently. All the inhibited forms of lipolytic enzymes described so far are based on the use of small organophosphate and organophosphonate inhibitors, which bear li
Autor:
G.H. de Haas, Maarten Robert Egmond, H. T. W. M. van der Hijden, A.T. Slotboom, M. L. M. Mannesse, J.-W.P. Boots, R. Dijkman, Hubertus M. Verheij
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1259:56-64
1,2-Dioctylcarbamoylglycero-3-O-p-nitrophenyl alkylphosphonates, with alkyl being methyl or octyl, were synthesised and tested as irreversible inhibitors of cutinase from Fusarium solani pisi and Staphylococcus hyicus lipase. Rapid inactivation of th
Autor:
G.H. de Haas, J. De Vlieg, Bart C. Koops, H. T. W. M. Van Der Hijden, Maarten Robert Egmond, Hubertus M. Verheij, Ruud C. Cox, M. L. M. Mannesse
Publikováno v:
Biochemistry. 34:6400-6407
Triglyceride analogues were synthesized in which one of the primary acyl ester functions has been replaced by an alkyl group and the secondary acyl ester bond has been replaced by an acyl amino bond. The chain length at either position was varied, an
Autor:
G.H. de Haas, Hubertus M. Verheij, Maarten Robert Egmond, H. T. W. M. van der Hijden, M. L. M. Mannesse
Publikováno v:
Biochemical Society transactions. 25(1)