Zobrazeno 1 - 10
of 15
pro vyhledávání: '"M. L. Kakhabrishvili"'
Publikováno v:
Chemistry of Natural Compounds. 58:178-180
Autor:
M. L. Kakhabrishvili, Vakhtang Mshvildadze, N. N. Barbakadze, N. Sh. Nadaraia, André Pichette, K. G. Mulkidzhanyan
Publikováno v:
Chemistry of Natural Compounds. 57:395-397
Autor:
N. N. Barbakadze, B. Sylla, M. L. Kakhabrishvili, N. Sh. Nadaraia, André Pichette, Vakhtang Mshvildadze, Jean Legault
Publikováno v:
Chemistry of Natural Compounds. 54:926-929
Steroidal hydrazones and pyrazolines were synthesized via condensation of a series of 5α-steroidal ketones with several hydrazines. Their cytotoxic activity against cancer cultures (A549 lung cancer, DLD-1 colorectal cancer, and WS1 normal skin fibr
Autor:
B. Sylla, N. N. Barbakadze, André Pichette, N. Sh. Nadaraia, M. L. Kakhabrishvili, U. S. Makhmudov
Publikováno v:
Chemistry of Natural Compounds
Several new N-containing epiandrosterone derivatives modified by phenylacetic acid chloride were synthesized for biological activity studies. Compounds with antiviral activity were discovered among them and 3β-hydroxy-1'-aryl-3'-methyl-5'-androstano
Autor:
N. Sh. Nadaraia, André Pichette, N. N. Barbakadze, M. L. Kakhabrishvili, B. Sylla, E. O. Onashvili
Publikováno v:
Chemistry of Natural Compounds
A study of the antiviral activity of several new hydrazones and amines and amides of 5α-steroids that were synthesized by us earlier found highly and moderately active compounds. The structures of the synthesized compounds were proven using IR, PMR,
Publikováno v:
Chemistry of Natural Compounds. 52:445-447
New peptide derivatives of 17β-amino-5α-androstan-3β-ol were synthesized. Their structures were elucidated using PMR and 13C NMR spectra and elemental analyses.
Publikováno v:
Chemistry of Natural Compounds. 48:423-425
The semicarbazone and isonicotinoylhydrazone of 5α-pregn-2-en-20-one, which was prepared from 3β-acetoxy-5α-pregn-16-en-20-one, were synthesized for the first time. The antituberculosis activity of these and semicarbazones and isonicotinoylhydrazo
Autor:
N. N. Barbakadze, M. Z. Getia, E. O. Onashvili, M. I. Sikharulidze, André Pichette, M. L. Kakhabrishvili, N. Sh. Nadaraia, U. S. Makhmudov
Publikováno v:
Chemistry of Natural Compounds.
New androstanopyrazolines and hydrazones were synthesized via acid-catalyzed condensation of the tigogenin transformation product 5α-pregnenolone with several hydrazines. Their structures were proved using IR and NMR spectroscopy and mass spectromet
Publikováno v:
Chemistry of Natural Compounds. 43:753-755
Autor:
Nana N. Barbakadze, M. L. Kakhabrishvili, M. I. Sikharulidze, K. G. Mulkidzhanyan, N. Sh. Nadaraia
Publikováno v:
Chemistry of Natural Compounds. 46:493-494
Steroidal oximes and their derivatives are known to exhibit anti-inflammatory, anticancer, and other types of physiological activity [1, 2]. In continuation of structure–activity relationship studies of 5 -steroids [3], we synthesized steroidal oxi