Výsledky vyhledávání - "M. L. Gilmore"

Graft rejection following HLA matched T-lymphocyte depleted bone marrow transplantation

Publikováno v: British Journal of Haematology. 63:221-230

Bone marrow graft rejection following HLA-matched bone marrow transplantation (BMT) for leukaemia has been a rare problem. However, with the introduction of T-lymphocyte depleted BMT, graft rejection is recognized as a new complication. At the Royal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16271a5c4c3e2e95cb7424bcd46fbcf
https://doi.org/10.1111/j.1365-2141.1986.tb05544.x

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The Addition of Granulocyte-Macrophage Colony-Stimulating Factor to Normal Bone Marrow Enhances Cell Cycle and Clonogenicity Irrespective of Cryopreservation

Autor: J. Gmur, M J. M. L. Gilmore, H. G. Prentice, J. Burger

Publikováno v: Cytokines in Hemopoiesis, Oncology, and AIDS II ISBN: 9783540552420

Ex vivo treatment of bone marrow with haematopoietic growth factors may prove to be a useful method for priming haematopoietic cells prior to autologous and allogeneic transplantation. This approach may reduce the period of post-transplant aplasia [1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::15c81851b08b0ef3ec04f0e8212dbc7f
https://doi.org/10.1007/978-3-642-48715-6_6

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Standardization of the Processing of Human Bone Marrow for Allogeneic Transplantation

Autor: M. J. M. L. Gilmore, H. G. Prentice

Publikováno v: Vox Sanguinis. 51:202-206

Allogeneic bone marrow transplantation has been undertaken within this centre on 62 patients with acute or chronic leukaemia. Employing the standard separation protocol described, all bone marrows were processed on the 2991 Blood Cell Processor to is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65645f33892bd2962fc469284807115d
https://doi.org/10.1159/000461492

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DEPLETION OF T LYMPHOCYTES IN DONOR MARROW PREVENTS SIGNIFICANT GRAFT-VERSUS-HOST DISEASE IN MATCHED ALLOGENEIC LEUKAEMIC MARROW TRANSPLANT RECIPIENTS

Autor: S. Graphakos, Hilary A. Blacklock, D. Skeggs, M. J. M. L. Gilmore, J. Patterson, H. G. Prentice, A. V. Hoffbrand, N. Tidman, L. Price-Jones, George Janossy, K. Ivory, S. Ball, L.K. Trejdosiewicz, D. D. Panjwani

Publikováno v: The Lancet. 323:472-476

For more than 15 years preclinical studies have suggested that acute graft-versus-host disease (aGvHD) might be prevented by the removal of immunocompetent T lymphocytes from the donor marrow inoculum. To test this observation in man 14 patients were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a3da767cf45f4fed069e06bbbefc27
https://doi.org/10.1016/s0140-6736(84)92848-4

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Standardization of T-cell depletion in HLA matched bone marrow transplantation

Autor: K. Ivory, S. Graphakos, M. J. M. L. Gilmore, A. V. Hoffbrand, H. G. Prentice, J. Patterson, Malcolm K. Brenner, George Janossy

Publikováno v: British Journal of Haematology. 64:69-75

Summary. The IBM 2991 Blood Cell Processor has been used to isolate a mononuclear cell (MNC) fraction from the marrow of 31 allogeneic donors. The MNC fraction was then incubated with a combination of two murine monoclonal antibodies MBG6 (CD6) and R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4eaef63aec9428d3fe14fc853c6adf4
https://doi.org/10.1111/j.1365-2141.1986.tb07574.x

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The role of monoclonal antibodies in the prevention of graft versus host disease

Autor: M. J. M. L. Gilmore, H. G. Prentice, H. A. Blacklock, George Janossy, A. V. Hoffbrand, K. Ivory

Publikováno v: Medical Oncology and Tumor Pharmacotherapy. 1:279-284

We have previously reported that the elimination of T-lymphocytes (greater than 99%) from the donor bone marrow prevents significant graft versus host disease (GvHD). This has been confirmed by other centres. Many of these groups have applied monoclo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0cc5fb0393df0f094889d5b0c4a4035
https://doi.org/10.1007/bf02934536

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ABO-INCOMPATIBLE BONE-MARROW TRANSPLANTATION: REMOVAL OF RED BLOOD CELLS FROM DONOR MARROW AVOIDING RECIPIENT ANTIBODY DEPLETION

Autor: M. J. M. L. Gilmore, C.B.T Knight, G. Hazlehurst, J.P.M Evans, David D.F. Ma, A. V. Hoffbrand, H. G. Prentice, Hilary A. Blacklock

Publikováno v: The Lancet. 320:1061-1064

Eight patients with acute leukaemia undergoing allogeneic bone-marrow transplantation from ABO-incompatible donors received red-cell-depleted donor marrow without any procedure to diminish their anti-ABO antibody titres. Successful marrow red-cell re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::577bd28a9cf2e4827907d979c573c837
https://doi.org/10.1016/s0140-6736(82)90003-4

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