Zobrazeno 1 - 10
of 27
pro vyhledávání: '"M. L. Disis"'
Autor:
K. L. Knutson, M. L. Disis
Publikováno v:
Clinical and Experimental Immunology. 135:322-329
SUMMARY CD4+ T cells are essential for the immune response against cancer. Vaccination against cancer will likely only be effective at preventing growth of micrometastatic disease while adoptive T cell therapy will be better suited for eradication of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da5ed54753ea91c7fc71c4f71ee8bbe
https://doi.org/10.1111/j.1365-2249.2004.02360.x
https://doi.org/10.1111/j.1365-2249.2004.02360.x
Autor:
M L, Disis, H, Bernhard, F M, Shiota, S L, Hand, J R, Gralow, E S, Huseby, S, Gillis, M A, Cheever
Publikováno v:
Blood. 88:202-210
The current studies evaluate granulocyte-macrophage colony-stimulating factor (GM-CSF) as a vaccine adjuvant. An important issue for developing vaccine therapy for human malignancy is identifying adjuvants that can elicit T-cell responses to proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adfc7f353846eea0e7269483ed1f5c64
https://doi.org/10.1182/blood.v88.1.202.202
https://doi.org/10.1182/blood.v88.1.202.202
Publikováno v:
The Journal of Immunology. 156:3151-3158
HER-2/neu, an overexpressed oncogenic protein, has been proposed as a human cancer vaccine target. HER-2/neu is a "self" protein, however, and methods of vaccine strategies that would be effective in immunizing patients to a "self" tumor Ag have not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9272475f795ddff2394614d40ce86c80
https://doi.org/10.4049/jimmunol.156.9.3151
https://doi.org/10.4049/jimmunol.156.9.3151
Autor:
M L, Disis, K, Schiffman
Publikováno v:
Seminars in oncology. 28(6 Suppl 18)
Several advances in basic immunology over the last few years have forced a re-evaluation of cancer vaccine development. The most important finding has been that human tumors are immunogenic. The HER2/neu oncogenic protein is a tumor antigen. Existent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bbb327b3b73570f72383d742ae49dfe7
https://pubmed.ncbi.nlm.nih.gov/11774201
https://pubmed.ncbi.nlm.nih.gov/11774201
Publikováno v:
Critical reviews in immunology. 21(1-3)
In the development of targeted cancer immunotherapies, the choice of antigen is obviously critical to the design of any therapeutic strategy, but particularly so for tumor vaccines, which must distinguish malignant cells from normal cells. Investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60a60075609e7451c4679c308c9b197f
https://pubmed.ncbi.nlm.nih.gov/11642608
https://pubmed.ncbi.nlm.nih.gov/11642608
Publikováno v:
Cancer research. 61(13)
Helper T cells (Th cells) play a central role in the initiation and maintenance of immune responses, including antitumor immunity. The ability of Th cells in murine models to maintain and enhance the cytolytic efficacy of CD8+ CTLs has led to a renew
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::326ea9887e15fe818f51b10286c6f7e1
https://pubmed.ncbi.nlm.nih.gov/11431355
https://pubmed.ncbi.nlm.nih.gov/11431355
Autor:
M L, Disis, K, Schiffman
Publikováno v:
Journal of immunotherapy (Hagerstown, Md. : 1997). 24(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3effe5fbadd7f79fff29037d1369d7cb
https://pubmed.ncbi.nlm.nih.gov/11265775
https://pubmed.ncbi.nlm.nih.gov/11265775
Publikováno v:
The Journal of urology. 164(5)
Several immune based therapies targeting prostate cancer associated proteins are currently undergoing clinical investigation. In general, however, little is known about the immunogenicity of prostate cancer or which prostate cancer associated protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::93cc501548376950a86b50792ebfa920
https://pubmed.ncbi.nlm.nih.gov/11025777
https://pubmed.ncbi.nlm.nih.gov/11025777
Publikováno v:
Blood. 96(4)
The Wilms' tumor (WT1) gene participates in leukemogenesis and is overexpressed in most types of leukemia in humans. WT1 is also detectable in many types of lung, thyroid, breast, testicular, and ovarian cancers and melanoma in humans. Initial studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e36ea61528e32ab9a0bc86aa61db5f7
https://pubmed.ncbi.nlm.nih.gov/10942395
https://pubmed.ncbi.nlm.nih.gov/10942395
Autor:
D G, McNeel, M L, Disis
Publikováno v:
Archivum immunologiae et therapiae experimentalis. 48(2)
Prostate cancer is a significant health problem and one of the leading causes of cancer-related death among men. Given the typically long natural history of the disease, there is considerable interest in developing new therapies to treat or prevent m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ea182a7ace2274dc62f2822f97d2dd68
https://pubmed.ncbi.nlm.nih.gov/10807048
https://pubmed.ncbi.nlm.nih.gov/10807048