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pro vyhledávání: '"M. Kukan"'
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Publikováno v:
Hepatology. 26:1250-1257
The mechanisms of liver injury from cold storage and reperfusion are not completely understood. The aim of the present study was to investigate: 1) whether the inactivation of Kupffer cells (KCs) by gadolinium chloride (GadCl) modulates cold ischemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987915a6784bc0f911621f496f872866
https://doi.org/10.1002/hep.510260524
https://doi.org/10.1002/hep.510260524
Autor:
M Kukan
Publikováno v:
Hepatology. 26:1250-1257
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2287933cc826674c715e23a9e68108f
https://doi.org/10.1053/jhep.1997.v26.pm0009362369
https://doi.org/10.1053/jhep.1997.v26.pm0009362369
Publikováno v:
Xenobiotica. 24:1107-1117
1. Incubations of tacrine (1,2,3,4-tetrahydro-9-acridinamine monohydrochloride monohydrate, THA) with a primary suspension of rat hepatocytes for 2 min resulted in formation of the 1-hydroxy derivative as the major metabolite with smaller amounts of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2efccf4dab802800e1e13ac57323c56
https://doi.org/10.3109/00498259409038670
https://doi.org/10.3109/00498259409038670
Autor:
D. Mihalová, Mária Ďurišová, Z. Kállay, Katarína Bauerová, P. Bohov, Štefan Bezek, Tomas Trnovec, V. Faberová, V. Koprda, V. Ščasnár, M. Kukan, L. Šortés
Publikováno v:
Life Sciences. 65:2003-2005
The aim of this paper is to provide a brief overview of most important results of stobadine kinetic studies in rats, dogs, and human volunteers. In these studies, stobadine dihydrochloride and stobadine dipalmitate was used for intravenous and oral a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbbcb209f1f01c06686ffdd34e10f587
https://doi.org/10.1016/s0024-3205(99)00465-8
https://doi.org/10.1016/s0024-3205(99)00465-8
Publikováno v:
Experientia. 46:1017-1020
The passage of 6 model drugs; acetylsalicylic acid, chloramphenicol, ethimizol, carbisocaine, heptacaine, and diazepam, through the blood-brain barrier, was determined in unirradiated control rats and in animals 1, 3, and 7 days after irradiation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa6a1f73fa931ad4db1b08bf29c07c8d
https://doi.org/10.1007/bf01940660
https://doi.org/10.1007/bf01940660
Publikováno v:
Biopharmaceutics & Drug Disposition. 11:403-409
Pentacaine, a local anaesthetic of the carbanilate type, administered intravenously as 3H-pentacaine, 2 mg kg-1 to rats, was eliminated in the bile mainly in the form of metabolites (20.5 +/- 1.5 per cent of the dose) and as parent drug (0.1 per cent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1621778016d04a6b92d418eddc86995
https://doi.org/10.1002/bdd.2510110505
https://doi.org/10.1002/bdd.2510110505
Publikováno v:
Biopharmaceutics & Drug Disposition. 11:395-401
The biliary excretion of 3H-pentacaine and its metabolites was studied in rats pretreated with an inducer or inhibitor of mixed-function oxidases. Over one-fourth (25.8 per cent) of a 2 mg kg-1 intraportal dose of 3H-pentacaine was excreted in bile i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1099b8f82768376ff3237c6eb373d846
https://doi.org/10.1002/bdd.2510110504
https://doi.org/10.1002/bdd.2510110504
Autor:
M Kukan
Publikováno v:
Gastroenterology. 112:1775-1777
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::080032e2e30edad6d531a8ff6cba1534
https://doi.org/10.1016/s0016-5085(97)70068-4
https://doi.org/10.1016/s0016-5085(97)70068-4
Publikováno v:
Ceskoslovenska fysiologie. 53(4)
Hypothermic preservation can increase hepatocyte sensitivity to various insults. Here we studied the hypothesis that hepatocytes are injured by manipulation with cold-preserved liver. Livers from Wistar rats were divided into two groups. In the 1st g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::71c55f18af5d96d17d3e5479fd4695a2
https://pubmed.ncbi.nlm.nih.gov/15704737
https://pubmed.ncbi.nlm.nih.gov/15704737