How Well do Polygenic Risk Scores Identify Men at High Risk for Prostate Cancer? Systematic Review and Meta-Analysis

Autor: Aino Siltari, Ragnar Lönnerbro, Karl Pang, Kirill Shiranov, Alex Asiimwe, Susan Evans-Axelsson, Billy Franks, Amit Kiran, Teemu J. Murtola, Jack Schalken, Carl Steinbeisser, Anders Bjartell, Anssi Auvinen, J. N’Dow, E.J. Smith, R. Shepherd, M. Ribal, N. Mottet, L. Moris, M. Lardas, P-P. Willemse, G. Gandaglia, R. Campi, Rossella Nicoletti, M. Gacci, A. Briganti, M.M. Ratti, E. Alleva, L. Leardini, E.S. Sisca, R. Bangma, M. Roobol, S. Remmers, D. Tilki, T. Visakorpi, K. Talala, T. Tammela, M. van Hemelrijck, K. Bayer, S. Lejeune, S. Byrne, L. Fialho, P. Palaiologou B. De Meulder, C. Auffray, A. Hijazy, S. Power, N. Zounemat Kermani, K. van Bochove, M. Kalafati, M. Moinat, E. Voss, D. Horgan, L. Fullwood, M. Holtorf, D. Lancet, G. Bernstein, I. Omar, S. MacLennan, S. Maclennan, S. Tripathee, M. Wirth, M. Froehner, B. Brenner, A. Borkowetz, C. Thomas, F. Horn, K. Reiche, M. Kreux, A. Josefsson, D. Gasi Tandefekt, J. Hugosson, H. Huisman, J. Schalken, T. Hofmacher, P. Lindgren, E. Andersson, A. Fridhammar, J. Zong, J-E. Butler-Ransohoff, R. Herrera, M. Maass, P. Torremante, M.D. Voss, Z. Devecseri, T. Abbott, C. Dau, K. Papineni, R. Snijder, M. Lambrecht, R. Wolfinger, S. Rogiers, A. Servan, L. Antoni, K. Pacoe, P. Robinson, B. Jaton, D. Bakkard, H. Turunen, O. Kilkku, P. Pohjanjousi, O. Voima, L. Nevalaita, C. Reich, S. Araujo, E. Longden-Chapman, D. Burke, P. Agapow, S. Derkits, M. Licour, C. McCrea, S. Payne, A. Yong, L. Thompson, S. Le Mare, M Bussmann, D. Kotik

Publikováno v: Clinical Genitourinary Cancer, 21, 2, pp. 316.e1-316.e11
Clinical Genitourinary Cancer, 21, 316.e1-316.e11

Contains fulltext : 291547.pdf (Publisher’s version ) (Open Access) OBJECTIVES: Genome-wide association studies have revealed over 200 genetic susceptibility loci for prostate cancer (PCa). By combining them, polygenic risk scores (PRS) can be gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aebe650dd619575ff9d0e1f7617b2c01
https://hdl.handle.net/2066/291547