Zobrazeno 1 - 10
of 188
pro vyhledávání: '"M. Koukourakis"'
Autor:
Christos Nanos, Ioannis M. Koukourakis, Admir Mulita, Raphaela Avgousti, Vassilios Kouloulias, Anna Zygogianni, Michael I. Koukourakis
Publikováno v:
Current Oncology, Vol 31, Iss 10, Pp 5774-5788 (2024)
Radiotherapy (RT)-induced lymphopenia may hinder the anti-tumor immune response. Preoperative RT or chemo-RT (CRT) for locally advanced rectal cancer is a standard therapeutic approach, while immunotherapy has been approved for mismatch repair-defici
Externí odkaz:
https://doaj.org/article/b3ee4f42d9ba4bc29bb61328e6b494f5
Autor:
Michael I. Koukourakis, Erasmia Xanthopoulou, Ioannis M. Koukourakis, Sotirios P. Fortis, Nikolaos Kesesidis, Christos Kakouratos, Ioannis Karakasiliotis, Constantin N. Baxevanis
Publikováno v:
Current Oncology, Vol 30, Iss 10, Pp 8902-8915 (2023)
Using next-generation sequencing (NGS), we investigated DNA mutations in the plasma tumor cell-free circulating DNA (ctDNA) of 38 patients with inoperable squamous cell head neck cancer (SCHNC) before and after the completion of chemoradiotherapy (CR
Externí odkaz:
https://doaj.org/article/211dacec8bca412db760aaebb76c20de
Autor:
Ioannis M. Koukourakis, Kalliopi Platoni, Dina Tiniakos, Vassilis Kouloulias, Anna Zygogianni
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 5, Pp 4495-4517 (2023)
It is well-established that tumor antigens and molecules expressed and secreted by cancer cells trigger innate and adaptive immune responses. These two types of anti-tumor immunity lead to the infiltration of the tumor’s microenvironment by immune
Externí odkaz:
https://doaj.org/article/8afd12743bf843b2a293c4d8e8dc84bb
Autor:
Ioannis M. Koukourakis, Erasmia Xanthopoulou, Michael I. Koukourakis, Dina Tiniakos, Vassilis Kouloulias, Anna Zygogianni
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 448 (2024)
The IFN-type-I pathway is involved in radiotherapy (RT)-mediated immune responses. Large RT fractions have been suggested to potently induce this pathway. Neoadjuvant hypofractionated short-course (scRT) and conventional long-course (lcRT) RT applied
Externí odkaz:
https://doaj.org/article/73f7894398124b558e654f4074731c28
Autor:
Ioannis M. Koukourakis, Anastasia G. Gkegka, Erasmia Xanthopoulou, Christos Nanos, Alexandra Giatromanolaki, Michael I. Koukourakis
Publikováno v:
Current Oncology, Vol 29, Iss 6, Pp 4274-4284 (2022)
Microenvironmental conditions control the entrance and thriving of cytotoxic lymphocytes in tumors, allowing or preventing immune-mediated cancer cell death. We investigated the role of tumor-infiltrating lymphocyte (TIL) density in the outcome of ra
Externí odkaz:
https://doaj.org/article/8ecceaa8a874421784c361a42168e83b
Autor:
Ioannis M. Koukourakis, Marianthi Panteliadou, Axiotis G. Giakzidis, Christos Nanos, Ioannis Abatzoglou, Alexandra Giatromanolaki, Michael I. Koukourakis
Publikováno v:
Current Oncology, Vol 28, Iss 5, Pp 3474-3487 (2021)
We report long-term results (median follow-up 12 years) of hypofractionated accelerated radiotherapy (HypoAR) in patients treated with breast-conserving surgery. In total, 367 women were treated with HypoAR. Axillary and supraclavicular area (ASA) we
Externí odkaz:
https://doaj.org/article/006be158547c43d6b0b9d5979df316d5
Publikováno v:
Human Pathology Reports, Vol 26, Iss , Pp 300561- (2021)
This case report presents the results of a pilot immuno-phenotypic evaluation of a MCPyV large T-antigen positive Merkel cell carcinoma (MCC). The overall results show a profound immunological imbalance in the MCC microenvironment. An evident prevale
Externí odkaz:
https://doaj.org/article/21b9c6deed214636a4a2b579d15716d0
Publikováno v:
Case Reports in Gastroenterology, Vol 12, Iss 1, Pp 170-175 (2018)
Heterotopic pancreatic tissue can be found in the gastrointestinal tract, with the stomach and small bowel being the most common sites of localization. The gallbladder is seldom affected. Here, we report 2 cases of ectopic pancreas within the fatty t
Externí odkaz:
https://doaj.org/article/942871a69140480ba87ec076dd158dbd
Publikováno v:
International Journal of Radiation Biology. 99:715-736
Radiotherapy (RT) and immunotherapy are powerful anti-tumor treatment modalities. Experimental research has demonstrated an important interplay between the cytotoxic effects of RT and the immune system. This systematic review provides an overview of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a65fc642ade03bd367aa31b8e572ebd9
https://doi.org/10.1080/09553002.2023.2144960
https://doi.org/10.1080/09553002.2023.2144960
Publikováno v:
Clinical and Translational Oncology.
Introduction Patients with recurrent inoperable squamous-cell head-neck cancer (HNSCC) after chemo-radiotherapy have an ominous prognosis. Re-irradiation can be applied with some efficacy and high toxicity rates. Anti-PD-1 immunotherapy is effective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6f7efa7d41074458c1afdfb0db3fd28
https://doi.org/10.1007/s12094-023-03172-y
https://doi.org/10.1007/s12094-023-03172-y