Zobrazeno 1 - 10
of 71
pro vyhledávání: '"M. Konstandin"'
Autor:
V. Kmietczyk, J. Oelschläger, E. Varma, S. Hartl, M. Konstandin, A. Marx, P. Gupta, Z. Loewenthal, V. Kamuf-Schenk, L. Jürgensen, C. Stroh, A. Gorska, T. Jakobi, N. Frey, M. Völkers
m6A mRNA methylation controls cardiomyocyte function and increased overall m6A levels are a stereotyping finding in heart failure independent of the underlying etiology. However, it is largely unknown how the information is read by m6A reader protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d7b36cd5d320089f5f0d2298adab0a2
https://doi.org/10.1101/2022.12.16.520765
https://doi.org/10.1101/2022.12.16.520765
Akademický článek
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Autor:
Clara Sandmann, Vivien Kmietczyk, Shirin Doroudgar, Carsten Sticht, Eva Riechert, Eshita Varma, M. Konstandin, Claudia Stroh, Jennifer Furkel, Verena Kamuf-Schenk, Hugo A. Katus, Lonny Juergensen, Ellen Malovrh, Agnieszka A. Gorska, Christoph Hofmann, Mirko Völkers, Christoph Dieterich, Etienne Boileau
The mechanistic target of rapamycin (mTOR) is a key regulator of pathological remodeling in the heart by activating ribosomal biogenesis and mRNA translation. Inhibition of mTOR in cardiomyocytes is protective, however, a detailed role of mTOR in tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e491c64b16a6be24f30139103725a0e
https://doi.org/10.1101/2020.11.29.403196
https://doi.org/10.1101/2020.11.29.403196
Autor:
M. Konstandin, Volker Eckstein, Nicolai V. Bogert, Lorenz Uhlmann, J A Müller, Jennifer Furkel, Hugo A. Katus, I Braren, Shabana Din
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Lentiviral modification of hematopoietic stem cells (HSCs) paved the way for in vivo experimentation and therapeutic approaches in patients with genetic disease. A disadvantage of this method is the use of a ubiquitous promoter leads not only to gene
Akademický článek
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Autor:
Andreas O. Doesch, M. Konstandin, Hugo A. Katus, Christian Erbel, Philipp Ehlermann, A. Koch, S. De Geest, Arnt V. Kristen, Thomas J. Dengler, S. Celik, Christian Zugck, Lutz Frankenstein, Susanne Mueller
Publikováno v:
Transplantation Proceedings. 42:4238-4242
Modified release tacrolimus (TAC) is a new, once-daily oral formulation of the established immunosuppressive agent TAC. Simplification of regimen has been associated with better adherence. This study evaluated patient adherence, as well as safety and
Autor:
Andreas O. Doesch, Hugo A. Katus, M. Konstandin, Arnt V. Kristen, Falk-Udo Sack, S. Celik, Susanne Müller, Philipp Ehlermann, Lutz Frankenstein, Thomas J. Dengler
Publikováno v:
Transplantation Proceedings. 42:3694-3699
The objectives of the present study were to evaluate the incidence of malignancies and to describe the effects of immunosuppression on survival and recurrence of malignancies after heart transplantation (HTX). Data were analyzed in 211 cardiac allogr
Autor:
Hugo A. Katus, Arnt V. Kristen, M. Konstandin, Kerstin Ammon, Thomas J. Dengler, Philipp A. Schnabel, Falk-Udo Sack, Andreas O. Doesch, S. Celik
Publikováno v:
Transplantation proceedings. 43(5)
Calcineurin inhibitor (CNI)-free immunosuppression is used increasingly after heart transplantation to avoid CNI toxicity, but in the absence of a randomized trial, concerns remain over an increased rejection risk.We studied the incidence of graft re
Autor:
S. Celik, Lutz Frankenstein, Hugo A. Katus, Arnt V. Kristen, Christian Erbel, Susanne Mueller, Andreas O. Doesch, A. Koch, M. Konstandin, Christian Zugck, Philipp Ehlermann
Publikováno v:
Transplantation proceedings. 42(10)
Background Proton pump inhibitors (PPIs) are often prescribed for gastrointestinal discomfort after heart transplantation. This study investigated the impact of PPI use on mycophenolic acid (MPA) pharmacokinetics in heart transplant recipients receiv
Akademický článek
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