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Akademický článek

Sex Specific Expression of Interleukin 7, 8 and 15 in Placentas of Women with Gestational Diabetes

Autor: Simon Keckstein, Sophia Pritz, Niklas Amann, Sarah Meister, Susanne Beyer, Magdalena Jegen, Christina Kuhn, Stefan Hutter, Julia Knabl, Sven Mahner, Thomas Kolben, Udo Jeschke, Theresa M. Kolben

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 21, p 8026 (2020)

Gestational diabetes mellitus (GDM) is known to increase the risk for feto-maternal complications during pregnancy. A state of low-grade inflammation, with elevated levels of proinflammatory molecules, similar to patients with obesity or diabetes mel

Externí odkaz: https://doaj.org/article/bf86d19fa60749019b56c181fca8fd7a

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Longitudinal assessment of ROPRO as an early indicator of overall survival in oncology clinical trials: a retrospective analysis

Autor: H. Loureiro, T. M. Kolben, A. Kiermaier, D. Rüttinger, N. Ahmidi, T. Becker, A. Bauer-Mehren

BackgroundThe gold standard to evaluate treatment efficacy in oncology clinical trials is Overall Survival (OS). Its utility, however, is limited by the need for long trial duration and large sample sizes. Thus methods such as Progression-Free Surviv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4eb1ffcdf004fc888a0b58215f3ae365
https://doi.org/10.1101/2022.10.11.22280399

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Late Presentation at Primary Diagnosis of Breast Cancer: Patients’ Personality Characteristics and Attitudes

Autor: Rachel Wuerstlein, Sanaz Ghasemi, Franz Koch, Nadia Harbeck, Theresa M. Kolben, S Beyer, S Meister, Anna Hester, Thomas Kolben, Sven Mahner, Kerstin Hermelink, Isabelle Himsl, Tom Degenhardt

Publikováno v: Breast Care (Basel)

Introduction: Breast cancer (BC) is the most common cancer in women worldwide. Despite screening and information efforts, about 10% of patients present with tumor size T3 or T4 at primary diagnosis. Late presentation is associated with more advanced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213a94e20825f13fd245165c3c1bd7e6
https://doi.org/10.1159/000509597

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Regulation of LCoR and RIP140 expression in cervical intraepithelial neoplasia and correlation with CIN progression and dedifferentiation

Autor: Sven Mahner, Tilman L. R. Vogelsang, Elisa Schmoeckel, Theresa M. Kolben, Helene Hildegard Heidegger, Aurelia Vattai, Thomas Kolben, Christina Kuhn, Udo Jeschke, Thomas Blankenstein, Mina Temelkov, Doris Mayr

Publikováno v: Journal of Cancer Research and Clinical Oncology

Purpose Ligand-dependent corepressor (LCoR) and receptor-interacting protein 140 (RIP140/NRIP1) play an important role in the regulation of multiple oncogenic signaling pathways and the development of cancer. LCoR and RIP140 form a nuclear complex in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da16fa34dc84f80a88a083c86e853ce8
https://doi.org/10.1007/s00432-020-03178-x

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Galectin-8 and -9 as prognostic factors for cervical cancer

Autor: Susanne Beyer, Maya Wehrmann, Sarah Meister, Theresa M. Kolben, Fabian Trillsch, Alexander Burges, Bastian Czogalla, Elisa Schmoeckel, Sven Mahner, Udo Jeschke, Thomas Kolben

Purpose Galectins are carbohydrate-binding proteins with multiple effects on cell biology. Research shows that they play an important role in tumor development and progression. Therefore, in this study, the presence of Galectin-8 and -9 (Gal), both a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e68c943cf44527e7155b3da8376826
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/94979

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Metastatic Breast Cancer: Is There a Differential Therapy Efficacy between Visceral and Non-Visceral Metastatic Breast Cancer?

Autor: Sven Mahner, Thomas Kolben, Nadia Harbeck, Laura Rickerl, Theresa M. Kolben, Maximilian Bardenhewer, Rachel Wuerstlein, Tom Degenhardt

Publikováno v: Breast Care (Basel)

Purpose: Differential efficacy of newly registered therapies in subgroups of metastatic breast cancer (MBC) is an important consideration for subsequent use in clinical practice. Unfortunately, such subgroup analyses often are exploratory and rarely

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b1cc5adb896c811088d8bf0dfa533d
https://doi.org/10.1159/000504527

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Regulation of Epigenetic Modifications in the Placenta during Preeclampsia: PPARγ Influences H3K4me3 and H3K9ac in Extravillous Trophoblast Cells

Autor: Viktoria von Schönfeldt, Christina Kuhn, Theresa M. Kolben, S Meister, Kritika Sudan, Udo Jeschke, S Beyer, Stefanie Corradini, Sven Mahner, Christian Schulz, Sophie Mitter, L Hahn, Thomas Kolben, Corinna Paul

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 22
International Journal of Molecular Sciences, Vol 22, Iss 12469, p 12469 (2021)

The aim of this study was to analyze the expression of peroxisome proliferator-activated receptor γ (PPARγ) and retinoid X receptor α (RxRα), a binding heterodimer playing a pivotal role in the successful trophoblast invasion, in the placental ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cec34fe4476f6e8512f4fb2daa2384f
http://europepmc.org/articles/PMC8622744

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Proinflammatorische Zytokine führen im Trophoblastenzellmodell zu einer Induktion der Sekretion von CCL22

Autor: V von Schönfeldt, M Mannewitz, S Meister, Sven Mahner, S Beyer, K Sudan, Stefanie Corradini, L Hahn, Theresa M. Kolben, Christian Schulz, Udo Jeschke, Mirjana Kessler, S Eren

Publikováno v: Kongressabstracts zur Gemeinsamen Jahrestagung der Österreichischen Gesellschaft für Gynäkologie und Geburtshilfe (OEGGG) und der Bayerischen Gesellschaft für Geburtshilfe und Frauenheilkunde e.V. (BGGF).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f241a961cc974aea401a0bb9878d6a0
https://doi.org/10.1055/s-0041-1730481

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Epigenetische Modifikationen durch H3K4me3 und H3K9acan der fetomaternalen Grenzzone der Plazenta im Abortgeschehen

Autor: U Hasbargen, S Meister, Thomas Kolben, Theresa M. Kolben, N Rogenhofer, S Mahner, Anna Hester, I.M Kellner, S Beyer, Udo Jeschke, M Kessler, Stefanie Corradini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::096ae2cde2db9c42c3bbc8d3c10af8a3
https://doi.org/10.1055/s-0041-1730484

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