Dynamic time warp analysis of individual symptom trajectories in patients with bipolar disorder

Autor: R. Mesbah, M. Koenders, A. T. Spijker, M. de Leeuw, A. M. van Hemert, E. J. Giltay

Publikováno v: European Psychiatry, Vol 66, Pp S578-S579 (2023)

Introduction Manic and depressive mood states in bipolar disorder (BD) may emerge from the non-linear relations between constantly changing mood symptoms exhibited as a complex dynamic system. Dynamic Time Warp (DTW) is an algorithm that may capture

Externí odkaz: https://doaj.org/article/6eb0560659af4ea5b03814bd2a310d00

TGFβ-mediated expression of TGFβ-activating integrins in SSc monocytes: disturbed activation of latent TGFβ?

Autor: A. van Caam, J. Aarts, T. van Ee, E. Vitters, M. Koenders, F. van de Loo, P. van Lent, F. van den Hoogen, R. Thurlings, M. C. Vonk, P. M. van der Kraan

Publikováno v: Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-9 (2020)

Abstract Introduction The pathophysiology of systemic sclerosis (SSc) is closely linked to overactive TGFβ signaling. TGFβ is produced and circulates in latent form, making its activation crucial for signaling. This activation can be mediated via i

Externí odkaz: https://doaj.org/article/62febe8d581a411eb1e85ab1a13c79e8

Postnatal corticosteroid response in neonates 32 weeks and relation with placental pathology

Autor: V M, Koenders, A, Appels, H L M, van Straaten, A C, Dutman, M A C, Hemels

Publikováno v: European journal of pediatrics.

Acute chorioamnionitis and maternal vascular malperfusion are associated with an increased risk of bronchopulmonary dysplasia. To prevent bronchopulmonary dysplasia, postnatal corticosteroids are given to preterm neonates. Clinical observations indic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3f2ad102a84f29dfb966e782e93a92d2
https://pubmed.ncbi.nlm.nih.gov/36318297

OP0097 PROOF-OF-CONCEPT OF FIBROBLAST-TARGETED PHOTODYNAMIC THERAPY IN HUMAN 3D SCLERODERMA SKIN MODEL AND BLEOMYCIN-INDUCED SKIN FIBROSIS IN MICE

Autor: D. Dorst, A. van Caam, E. Vitters, B. Walgreen, M. Helsen, C. Klein, S. Gudi, T. Wubs, J. Kumari, P. Błyszczuk, M. Vonk, P. van der Kraan, M. Koenders

Publikováno v: Annals of the Rheumatic Diseases. 81:64-65

BackgroundSystemic sclerosis (SSc) is a rare, severe auto-immune disease characterized by inflammation, vasculopathy and fibrosis. Activated (myo)fibroblasts are crucial drivers of fibrosis. By exploiting their expression of fibroblast activation pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f1600ed5cd529c411e1db6cbd76eb6fa
https://doi.org/10.1136/annrheumdis-2022-eular.3151

Nationwide implementation of a decision aid on vaginal birth after cesarean: a before and after cohort study

Autor: Vivienne M. Koenders, Rosella P.M.G. Hermens, Sander M. J. van Kuijk, Martijn A. Oudijk, Hubertina C.J. Scheepers, Luc J.M. Smits, Merel S. F. van Hees, Maureen T.M. Franssen, Mireille N. Bekker, Dorothea M. Koppes

Publikováno v: Journal of Perinatal Medicine, 49(7), 783-790. Walter de Gruyter GmbH
Journal of Perinatal Medicine, 49(7), 783-790. De Gruyter
Journal of perinatal medicine, 49(7), 783-790. Walter de Gruyter GmbH
Journal of Perinatal Medicine, 49, 7, pp. 783-790
Journal of Perinatal Medicine, 49, 783-790

Objectives Woman with a history of a previous cesarean section (CS) can choose between an elective repeat CS (ERCS) and a trial of labor (TOL), which can end in a vaginal birth after cesarean (VBAC) or an unplanned CS. Guidelines describe women’s r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd035531710f51593ac788722de4eb3
https://research.rug.nl/en/publications/effbd7d5-49c6-47e7-b6e7-373565d55092