Zobrazeno 1 - 10
of 340
pro vyhledávání: '"M. Knudson"'
Publikováno v:
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, Vol XL-7/W3, Pp 1163-1170 (2015)
Unmanned aircraft systems (UAS) are important assets for accessing high risk airspace and incorporate technologies for sensor coordination, onboard processing, tele-communication, unconventional flight control, and ground based monitoring and optimiz
Externí odkaz:
https://doaj.org/article/634f9c01d25c41819a15101df78a757e
Autor:
Curtis J. Pritzl, Dezzarae Luera, Karin M. Knudson, Michael J. Quaney, Michael J. Calcutt, Mark A. Daniels, Emma Teixeiro
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract CD8+ T cell tissue resident memory (TRM) cells are especially suited to control pathogen spread at mucosal sites. However, their maintenance in lung is short-lived. TCR-dependent NFkB signaling is crucial for T cell memory but how and when N
Externí odkaz:
https://doaj.org/article/8618125c2d3f4f26b08eaa38d8d3c4c7
Autor:
Kristin C. Hicks, Paul L. Chariou, Yohei Ozawa, Christine M. Minnar, Karin M. Knudson, Thomas J. Meyer, Jing Bian, Margaret Cam, Jeffrey Schlom, Sofia R. Gameiro
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
The immunocytokine NHS-IL12 is targeted to necrotic tumour areas to prompt an immune response. Authors show here in mouse colon and breast models that the combination of histone deacetylase inhibitor, Entinostat, and NHS-IL12 generates a tumour micro
Externí odkaz:
https://doaj.org/article/9ae4f4dff32d41159c913dd23783fab3
Autor:
Karin M. Knudson, SuJin Hwang, Mondona S. McCann, Bharat H. Joshi, Syed R. Husain, Raj K. Puri
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Interleukin-13 receptor subunit alpha-2 (IL-13Rα2, CD213A), a high-affinity membrane receptor of the anti-inflammatory Th2 cytokine IL-13, is overexpressed in a variety of solid tumors and is correlated with poor prognosis in glioblastoma, colorecta
Externí odkaz:
https://doaj.org/article/8979ded1b3ab4206a768a27142c9599b
Autor:
Margaret E. Gatti-Mays, Sofia R. Gameiro, Yohei Ozawa, Karin M. Knudson, Kristin C. Hicks, Claudia Palena, Lisa M. Cordes, Seth M. Steinberg, Deneise Francis, Fatima Karzai, Stanley Lipkowitz, Renee N. Donahue, Caroline Jochems, Jeffrey Schlom, James L. Gulley
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Breast tumors commonly harbor low mutational burden, low PD-L1 expression, defective antigen processing/presentation, and an immunosuppressive tumor microenvironment (TME). In a malignancy mostly refractory to checkpoint blockade, there is an unmet c
Externí odkaz:
https://doaj.org/article/3b635c718c7d46879728beddc14329cb
Autor:
Yohei Ozawa, Kristin C. Hicks, Christine M. Minnar, Karin M. Knudson, Jeffrey Schlom, Sofia R. Gameiro
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Most monoclonal antibodies (MAbs), including immune checkpoint inhibitor MAbs, are delivered intravenously (i.v.) to patients. Recent clinical studies have demonstrated that some anti-PD1 MAbs may also be delivered subcutaneously (s.c.), with clinica
Externí odkaz:
https://doaj.org/article/50767b5a22ba444eb449605c918b8780
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Anti(α)-programmed cell death-1 (PD-1)/programmed death-ligand 1 (PD-L1) monotherapy fails to provide durable clinical benefit for most patients with carcinoma. Recent studies suggested that strategies to reduce immunosuppressive cells, p
Externí odkaz:
https://doaj.org/article/b984e9df55074ee3a0bdf992847f29db
Publikováno v:
Forest Products Journal. 72:29-36
Glued Laminated Timber, commonly referred to as Glulam, is an important structural wood product, suitable for use in exterior applications provided it is protected against decay by building design, natural durability, or treatment. Bonding treated la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c7f5e6ce84d51dce9d6c934f0d5e354
https://doi.org/10.13073/fpj-d-21-00067
https://doi.org/10.13073/fpj-d-21-00067
Autor:
Joseph J. Cullen, Charles M. Knudson, Changbin Du, Agshin F. Taghiyev, Sih-han Wang, Garry R. Buettner, Brett A. Wagner, Mark Levine, Sean M. Martin, Juan Du
Purpose: Pharmacologic concentrations of ascorbate may be effective in cancer therapeutics. We hypothesized that ascorbate concentrations achievable with i.v. dosing would be cytotoxic in pancreatic cancer for which the 5-year survival is Experimenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a12039fde554cde44361acacc40daa2
https://doi.org/10.1158/1078-0432.c.6517611
https://doi.org/10.1158/1078-0432.c.6517611
Autor:
Sofia R. Gameiro, Jeffrey Schlom, Patrick Soon-Shiong, Shahrooz Rabizadeh, Frank R. Jones, Peter Ordentlich, William D. Figg, James W. Hodge, Duane H. Hamilton, Karin L. Lee, Karin M. Knudson, Kristin C. Hicks
Purpose:Immunotherapy has demonstrated clinical efficacy in subsets of patients with solid carcinomas. Multimodal therapies using agents that can affect different arms of the immune system and/or tumor microenvironment (TME) might increase clinical r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257ac866c6a46a82c5d0490c769eeba2
https://doi.org/10.1158/1078-0432.c.6528504.v1
https://doi.org/10.1158/1078-0432.c.6528504.v1