Zobrazeno 1 - 10
of 2 867
pro vyhledávání: '"M. Knudson"'
Autor:
Curtis J. Pritzl, Dezzarae Luera, Karin M. Knudson, Michael J. Quaney, Michael J. Calcutt, Mark A. Daniels, Emma Teixeiro
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract CD8+ T cell tissue resident memory (TRM) cells are especially suited to control pathogen spread at mucosal sites. However, their maintenance in lung is short-lived. TCR-dependent NFkB signaling is crucial for T cell memory but how and when N
Externí odkaz:
https://doaj.org/article/8618125c2d3f4f26b08eaa38d8d3c4c7
Autor:
Kristin C. Hicks, Paul L. Chariou, Yohei Ozawa, Christine M. Minnar, Karin M. Knudson, Thomas J. Meyer, Jing Bian, Margaret Cam, Jeffrey Schlom, Sofia R. Gameiro
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
The immunocytokine NHS-IL12 is targeted to necrotic tumour areas to prompt an immune response. Authors show here in mouse colon and breast models that the combination of histone deacetylase inhibitor, Entinostat, and NHS-IL12 generates a tumour micro
Externí odkaz:
https://doaj.org/article/9ae4f4dff32d41159c913dd23783fab3
Autor:
Haskell, Theodore J.
Publikováno v:
NACTA Journal, 1981 Mar 01. 25(1), 21-22.
Externí odkaz:
https://www.jstor.org/stable/43763731
Autor:
Lowell Caneday
Publikováno v:
Journal of Leisure Research. 28:216-218
Douglas M. Knudson, Ted T. Cable & Larry Beck. (1995). Interpretation of Cultural and Natural Resources. State College, PA: Venture Publishing, Inc. ISBN 0-910251-703 $35.95 hardcover, 509 pages. Occasionally a book, designed as a text, provides such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::862c009912906461210d6da83db581b5
https://doi.org/10.1080/00222216.1996.11949772
https://doi.org/10.1080/00222216.1996.11949772
Autor:
Karin M. Knudson, SuJin Hwang, Mondona S. McCann, Bharat H. Joshi, Syed R. Husain, Raj K. Puri
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Interleukin-13 receptor subunit alpha-2 (IL-13Rα2, CD213A), a high-affinity membrane receptor of the anti-inflammatory Th2 cytokine IL-13, is overexpressed in a variety of solid tumors and is correlated with poor prognosis in glioblastoma, colorecta
Externí odkaz:
https://doaj.org/article/8979ded1b3ab4206a768a27142c9599b
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-16 (2019)
Abstract Background Immunotherapy targeting PD-1/PD-L1 fails to induce clinical responses in most patients with solid cancers. N-803, formerly ALT-803, is an IL-15 superagonist mutant and dimeric IL-15RαSushi-Fc fusion protein complex that enhances
Externí odkaz:
https://doaj.org/article/01c44dbd09c141fa93bc655b4604641d
Autor:
Margaret E. Gatti-Mays, Sofia R. Gameiro, Yohei Ozawa, Karin M. Knudson, Kristin C. Hicks, Claudia Palena, Lisa M. Cordes, Seth M. Steinberg, Deneise Francis, Fatima Karzai, Stanley Lipkowitz, Renee N. Donahue, Caroline Jochems, Jeffrey Schlom, James L. Gulley
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Breast tumors commonly harbor low mutational burden, low PD-L1 expression, defective antigen processing/presentation, and an immunosuppressive tumor microenvironment (TME). In a malignancy mostly refractory to checkpoint blockade, there is an unmet c
Externí odkaz:
https://doaj.org/article/3b635c718c7d46879728beddc14329cb
Autor:
Yohei Ozawa, Kristin C. Hicks, Christine M. Minnar, Karin M. Knudson, Jeffrey Schlom, Sofia R. Gameiro
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Most monoclonal antibodies (MAbs), including immune checkpoint inhibitor MAbs, are delivered intravenously (i.v.) to patients. Recent clinical studies have demonstrated that some anti-PD1 MAbs may also be delivered subcutaneously (s.c.), with clinica
Externí odkaz:
https://doaj.org/article/50767b5a22ba444eb449605c918b8780
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Anti(α)-programmed cell death-1 (PD-1)/programmed death-ligand 1 (PD-L1) monotherapy fails to provide durable clinical benefit for most patients with carcinoma. Recent studies suggested that strategies to reduce immunosuppressive cells, p
Externí odkaz:
https://doaj.org/article/b984e9df55074ee3a0bdf992847f29db
Autor:
Caroline Jochems, Sarah R. Tritsch, Karin M. Knudson, Sofia R. Gameiro, Claire Smalley Rumfield, Samuel T. Pellom, Y. Maurice Morillon, Robby Newman, Warren Marcus, Christopher Szeto, Shahrooz Rabizadeh, Hing C. Wong, Patrick Soon-Shiong, Jeffrey Schlom
Publikováno v:
OncoImmunology, Vol 8, Iss 2 (2019)
Here we describe a novel bifunctional fusion protein, designated N-809. This molecule comprises the IL-15/IL15Rα superagonist complex containing the Fc-domain of IgG1 (N-803, formerly designated as ALT-803) fused to two single chain anti-PD-L1 domai
Externí odkaz:
https://doaj.org/article/44c44230f6754047981633a4bd819a06