Výsledky vyhledávání

Evidence in action--guidelines directing workload

Autor: T Tala, M Klockars, Eeva Ketola, R Sipilä

Publikováno v: BMJ Quality & Safety. 19:514-518

Objective To approximate the workload of blood pressure (BP) measurements and lifestyle counselling in primary healthcare when the related guidelines are followed. To evaluate the impact of facilitated guideline implementation with respect to workloa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f07a83a4cd6c4709d1460bdfabff3681
https://doi.org/10.1136/qshc.2008.027987

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The Narcotrend Index Indicates Age-Related Changes During Propofol Induction in Children

Autor: Tomi Taivainen, Michael Winterhalter, Sinikka Münte, Matthias Gross, Christina Quandt, Mark van Gils, Arja Hiller, Jaakko G. M. Klockars

Publikováno v: Muente, S, Klockars, J, van Gils, M, Quandt, C, Gross, M, Hiller, A & Taivainen, T 2008, ' Narcotrend index indicates age-related changes during propofol induction in children ', Anesthesia and Analgesia, vol. 109, no. 1, pp. 53-59 . https://doi.org/10.1213/ane.0b013e3181a49c98

BACKROUND: The Narcotrend® electr oencephalogram monitor is designed to measure hypnotic state during anesthesia. We performed this study to evaluate the effectiveness and reliability of the Narcotrend monitor in assessing hypnotic state and loss of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bb164cf311ee46f4152819f52cc3315
https://doi.org/10.1213/ane.0b013e3181a49c98

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The performance of Bispectral Index in children during equi-MAC halothane vs. sevoflurane anaesthesia

Autor: Arja Hiller, Tomi Taivainen, Pertti K. Suominen, M. J. van Gils, J. Wennervirta, Jaakko G. M. Klockars

Publikováno v: Taivainen, T, Klockars, J, Hiller, A, Wennervirta, J, van Gils, M & Suominen, P 2008, ' The performance of Bispectral Index in children during equi-MAC halothane vs. sevoflurane anaesthesia ', European Journal of Anaesthesiology, vol. 25, no. 11, pp. 933-939 . https://doi.org/10.1017/S0265021508004845

Background and objective: The reliability of the Bispectral Index for evaluating and monitoring the depth of general anaesthesia in children is not as great as for that in adults. Therefore we analysed Bispectral Index performance in children by comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8435811b914a90ba616665a4c091bfa9
https://doi.org/10.1017/s0265021508004845

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The Air-Leak Test Is Not a Good Predictor of Postextubation Adverse Events in Children Undergoing Cardiac Surgery

Autor: Tomi Taivainen, Jaakko G. M. Klockars, Jukka T. Salminen, Olli A. Meretoja, Netta Tuominen, Reijo Korpela, Pertti K. Suominen

Publikováno v: Journal of Cardiothoracic and Vascular Anesthesia. 21:197-202

Objective: The air-leak test is recommended as a method of assessing the appropriate size of an uncuffed endotracheal tube (ETT) in children. The authors’ primary objective was to determine whether the air-leak test would predict adverse events and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::375bb4c3dd95f9d04c5883340b136dd9
https://doi.org/10.1053/j.jvca.2006.01.007

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Autor: Timo Hinrichs, Juhani Ilmarinen, M Klockars, Mikaela B. von Bonsdorff, Jorma Seitsamo, Monika E. von Bonsdorff, Jenni Kulmala, Timo Törmäkangas, Clas-Håkan Nygård, Taina Rantanen

Publikováno v: AGE. 36

The aim of this study is to investigate whether work-related stress symptoms in midlife are associated with a number of mobility limitations during three decades from midlife to late life. Data for the study come from the Finnish Longitudinal Study o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfba8fdbe76a15c1e5f2d98218876537
https://doi.org/10.1007/s11357-014-9722-4

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Bioactive glasses induce chemiluminescence by human polymorphonuclear leukocytes

Autor: M. Klockars, N. C. Lindfors, Heimo Ylänen

Publikováno v: Journal of Biomedical Materials Research. 47:91-94

The effect of bioactive glasses on human polymorphonuclear leukocytes (PMNLs) were studied in vitro by a chemiluminescence (CL) assay. Eight different glasses were chosen. All glasses induced a rapid CL response by human PMNLs, which proved to be dos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77ac1c06f097b599f19f8abd6e6d29ca
https://doi.org/10.1002/(sici)1097-4636(199910)47:1<91::aid-jbm13>3.0.co

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Different Contributions of Cytochrome P450 2E1 and P450 2B1/2 to Chloroform Hepatotoxicity in Rat

Autor: Harri Vainio, Eivor Elovaara, Vesa Riihimäki, Tamie Nakajima, M. Klockars, Toshifumi Aoyama, Harry V. Gelboin, T. Okino

Publikováno v: Toxicology and Applied Pharmacology. 133:215-222

The contribution of cytochrome P450 isozymes CYP2E1 and CYP2B1/2 to chloroform-induced hepatotoxicity taken at 18 hr after the treatment was investigated in rats treated with n-hexane as an inducer of CYP2E1, 2-hexanone as an inducer of CYP2E1 and CY

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a78ad067482cd22137792144344912df
https://doi.org/10.1006/taap.1995.1144

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Spectral entropy as a measure of hypnosis and hypnotic drug effect of total intravenous anesthesia in children during slow induction and maintenance

Autor: Tomi Taivainen, Arja Hiller, Sinikka Münte, Jaakko G. M. Klockars, Mark van Gils

Publikováno v: Klockars, J G M, Hiller, A, Münte, S, van Gils, M & Taivainen, T 2012, ' Spectral entropy as a measure of hypnosis and hypnotic drug effect of total intravenous anesthesia in children during slow induction and maintenance ', Anesthesiology, vol. 116, no. 2, pp. 340-351 . https://doi.org/10.1097/ALN.0b013e3182410b5e

Background We evaluated whether spectral entropy (SpE) can measure the depth of hypnosis and the hypnotic drug effect in children during total intravenous anesthesia. Methods Sixty healthy children, aged 3-16 yr, were studied. Anesthesia was induced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7772bc0c560cdeb886bf6bf9904cd7f0
https://cris.vtt.fi/en/publications/e35dd754-62f0-4709-a714-55c748d1e27f

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Spectral entropy as a measure of hypnosis in children

Autor: Arja Hiller, Tomi Taivainen, Jaakko G. M. Klockars, Pia Talja, Mark van Gils, Seppo Ranta

Publikováno v: Klockars, J G M, Hiller, A, Ranta, S, Talja, P, van Gils, M & Taivainen, T 2006, ' Spectral entropy as a measure of hypnosis in children ', Anesthesiology, vol. 104, no. 4, pp. 708-717 . < http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1926208 >

Background The Datex-Ohmeda S/5 Entropy Module (Datex-Ohmeda Division, Instrumentarium Corp., Helsinki, Finland), using time-frequency balanced Spectral Entropy, is a novel tool for monitoring the hypnotic state during anesthesia. The Entropy Module

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d35326fdb4c0a64c06b019316b11d68
https://cris.vtt.fi/en/publications/a23d99ac-0149-402a-9b06-1b9d371b7c12

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Immunoglobulin enhances the bioactive-glass-induced chemiluminescence response of human polymorphonuclear leukocytes

Autor: N C, Lindfors, M, Klockars

Publikováno v: Journal of biomedical materials research. 55(4)

Bioactive glasses are bone substitutes that chemically bind to bone. Implanted materials always elicit a response from surrounding tissues and thereby can activate inflammatory cells, with subsequent release of biomaterial and tissue-damaging agents.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2658e1b6492818cdc68decff2e2f1039
https://pubmed.ncbi.nlm.nih.gov/11288090

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