Zobrazeno 1 - 10
of 29
pro vyhledávání: '"M. Klarenbeek"'
Autor:
Alex R. Schuurman, Joe M. Butler, Erik H.A. Michels, Natasja A. Otto, Xanthe Brands, Bastiaan W. Haak, Fabrice Uhel, Augustijn M. Klarenbeek, Daniël R. Faber, Bauke V. Schomakers, Michel van Weeghel, Alex F. de Vos, Brendon P. Scicluna, Riekelt H. Houtkooper, W. Joost Wiersinga, Tom van der Poll
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107181- (2023)
Summary: Neutrophils are potent immune cells with key antimicrobial functions. Previous in vitro work has shown that neutrophil effector functions are mainly fueled by intracellular glycolysis. Little is known about the state of neutrophils still in
Externí odkaz:
https://doaj.org/article/4e949718e4164c9fb99adf50b5dffd0d
Autor:
Xanthe Brands, Bastiaan W. Haak, Augustijn M. Klarenbeek, Joe Butler, Fabrice Uhel, Wanhai Qin, Natasja A. Otto, Marja E. Jakobs, Daniël R. Faber, René Lutter, W. Joost Wiersinga, Tom van der Poll, Brendon P. Scicluna
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-17 (2021)
Abstract Background The plasticity of monocytes enables them to exert multiple roles during an immune response, including promoting immune tolerance. How monocytes alter their functions to convey immune tolerance in the context of lower respiratory t
Externí odkaz:
https://doaj.org/article/b06b9c428497488dbd62d7b688aaab55
Autor:
Robert F.J. Kullberg, Xanthe Brands, Augustijn M. Klarenbeek, Joe M. Butler, Natasja A. Otto, Daniël R. Faber, Brendon P. Scicluna, Tom van der Poll, W. Joost Wiersinga, Bastiaan W. Haak
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104740- (2022)
Summary: Human studies describing the immunomodulatory role of the intestinal microbiota in systemic infections are lacking. Here, we sought to relate microbiota profiles from 115 patients with community-acquired pneumonia (CAP), both on hospital adm
Externí odkaz:
https://doaj.org/article/66433c03a1ff48519f96542990b54e96
Autor:
Hina N. Khan, Xanthe Brands, Simona Aufiero, Arie J. Hoogendijk, Augustijn M. Klarenbeek, Tjitske S. R. van Engelen, Bastiaan W. Haak, Lonneke A. van Vught, Janneke Horn, Marcus J. Schultz, Aeilko H. Zwinderman, Tom van der Poll, Brendon P. Scicluna
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-12 (2020)
Abstract Background Dysregulation of the host immune response is a pathognomonic feature of sepsis. Abnormal physiological conditions are understood to shift efficient linear splicing of protein-coding RNA towards non-canonical splicing, characterize
Externí odkaz:
https://doaj.org/article/513972d7beef4ee78770d62e5c16ca46
Autor:
Lea M. Klarenbeek
Publikováno v:
Comparative Migration Studies, Vol 7, Iss 1, Pp 1-8 (2019)
Abstract In this essay, I respond to Schinkel’s recent statement that ‘any claim and practice that concerns ‘integration’ should be the object of research, rather than the project of research’ (2018, p. 8). Although I agree with Schinkel th
Externí odkaz:
https://doaj.org/article/d35cc4d4d9364d80919d0cc3d609eda1
Autor:
Xanthe Brands, Bastiaan W. Haak, Augustijn M. Klarenbeek, Natasja A. Otto, Daniël R. Faber, René Lutter, Brendon P. Scicluna, W. Joost Wiersinga, Tom van der Poll
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/be43d72b84be4a4796a245a1618bff3d
Autor:
Xanthe Brands, Bastiaan W. Haak, Augustijn M. Klarenbeek, Natasja A. Otto, Daniël R. Faber, René Lutter, Brendon P. Scicluna, W. Joost Wiersinga, Tom van der Poll
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
BackgroundThe nature and timing of the host immune response during infections remain uncertain and most knowledge is derived from critically ill sepsis patients. We aimed to test the hypothesis that community-acquired pneumonia (CAP) is associated wi
Externí odkaz:
https://doaj.org/article/d66e6163c0b24524b982edac1b25ad08
Autor:
Xanthe Brands, Tjitske S R van Engelen, Floris M C de Vries, Bastiaan W Haak, Augustijn M Klarenbeek, Maadrika M N P Kanglie, Inge A H van den Berk, Alex R Schuurman, Hessel Peters-Sengers, Natasja A Otto, Daniël R Faber, René Lutter, Brendon P Scicluna, Jaap Stoker, Jan M Prins, W Joost Wiersinga, Tom van der Poll
Publikováno v:
Journal of Infectious Diseases, 225(11), 2023-2032. Oxford University Press
Brands, X, van Engelen, T S R, de Vries, F M C, Haak, B W, Klarenbeek, A M, Kanglie, M M N P, van den Berk, I A H, Schuurman, A R, Peters-Sengers, H, Otto, N A, Faber, D R, Lutter, R, Scicluna, B P, Stoker, J, Prins, J M, Joost Wiersinga, W & van der Poll, T 2022, ' Association of Hyperferritinemia with Distinct Host Response Aberrations in Patients with Community-Acquired Pneumonia ', Journal of Infectious Diseases, vol. 225, no. 11, pp. 2023-2032 . https://doi.org/10.1093/infdis/jiac013
Journal of infectious diseases, 225(11), 2023-2032. Oxford University Press
Brands, X, van Engelen, T S R, de Vries, F M C, Haak, B W, Klarenbeek, A M, Kanglie, M M N P, van den Berk, I A H, Schuurman, A R, Peters-Sengers, H, Otto, N A, Faber, D R, Lutter, R, Scicluna, B P, Stoker, J, Prins, J M, Joost Wiersinga, W & van der Poll, T 2022, ' Association of Hyperferritinemia with Distinct Host Response Aberrations in Patients with Community-Acquired Pneumonia ', Journal of Infectious Diseases, vol. 225, no. 11, pp. 2023-2032 . https://doi.org/10.1093/infdis/jiac013
Journal of infectious diseases, 225(11), 2023-2032. Oxford University Press
Background Strongly elevated ferritin levels have been proposed to reflect systemic hyperinflammation in patients admitted to the intensive care unit. Knowledge of the incidence and pathophysiological implications of hyperferritinemia in patients wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be22649079468e52a8d39369f7f8560
https://research.vumc.nl/en/publications/61924e04-330c-4644-bc1d-467505ceb86a
https://research.vumc.nl/en/publications/61924e04-330c-4644-bc1d-467505ceb86a
Autor:
Marjukka Weide, Lea M. Klarenbeek
Publikováno v:
Critical Policy Studies, 14(2), 214-232. Routledge
In this paper, we address the ambivalence in European immigrant integration discourses toward the political participation of immigrants. We show how this ambivalence manifests in what we call a ‘participation paradox’, which is constituted by two
Autor:
René Lutter, Augustijn M. Klarenbeek, Natasja A. Otto, Brendon P. Scicluna, Bastiaan W. Haak, Wanhai Qin, Joe M. Butler, Marja E. Jakobs, Daniël R. Faber, Tom van der Poll, Fabrice Uhel, Xanthe Brands, W. Joost Wiersinga
Publikováno v:
Genome Medicine
Genome medicine, 13(1):131. BioMed Central
Genome Medicine, Vol 13, Iss 1, Pp 1-17 (2021)
Genome medicine, 13(1):131. BioMed Central
Genome Medicine, Vol 13, Iss 1, Pp 1-17 (2021)
Background: The plasticity of monocytes enables them to exert multiple roles during an immune response, including promoting immune tolerance. How monocytes alter their functions to convey immune tolerance in the context of lower respiratory tract inf