Zobrazeno 1 - 10
of 11
pro vyhledávání: '"M. Keith Wyatt"'
Autor:
M Keith Wyatt, Jen-Yue Tsai, Sanghamitra Mishra, Maria Campos, Cynthia Jaworski, Robert N Fariss, Steven L Bernstein, Graeme Wistow
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e68088 (2013)
Age-related macular degeneration (AMD) is a major cause of vision loss. It is associated with development of characteristic plaque-like deposits (soft drusen) in Bruch's membrane basal to the retinal pigment epithelium (RPE). A sequence variant (Y402
Externí odkaz:
https://doaj.org/article/029da03edf9c48afbf9206c48f9882df
Autor:
M. Keith Wyatt, Phillip Cai, Katherine Peterson, Jianguo Fan, Joshua Lerner, Lijin Dong, Graeme Wistow
Publikováno v:
Experimental Eye Research. 169:111-121
KLPH/lctl belongs to the Klotho family of proteins. Expressed sequence tag analyses unexpectedly revealed that KLPH is highly expressed in the eye lens while northern blots showed that expression is much higher in the eye than in other tissues. In si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a00f6acd91669396695ed3f18ae30c
https://doi.org/10.1016/j.exer.2018.02.001
https://doi.org/10.1016/j.exer.2018.02.001
Autor:
Graeme, Wistow, Steven L, Bernstein, Sugata, Ray, M Keith, Wyatt, Amita, Behal, Jeffrey W, Touchman, Gerald, Bouffard, Don, Smith, Katherine, Peterson
Publikováno v:
Molecular vision. 8
The iris is a specialized tissue with important roles in the development and function of the eye. It is involved in diseases, including glaucoma and ocular melanoma, and its pigmented cells share an origin with the retinal pigment epithelium (RPE). E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4b1c7d5c84b925fe70abbf8f8de743d
https://pubmed.ncbi.nlm.nih.gov/12107412
https://pubmed.ncbi.nlm.nih.gov/12107412
Autor:
Graeme, Wistow, Steven L, Bernstein, M Keith, Wyatt, Amita, Behal, Jeffrey W, Touchman, Gerald, Bouffard, Don, Smith, Katherine, Peterson
Publikováno v:
Molecular vision. 8
To explore the expression profile of the human lens and to provide a resource for microarray studies, expressed sequence tag (EST) analysis has been performed on cDNA libraries from adult lenses.A cDNA library was constructed from two adult (40 year
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::33fc50c1eeee61bf6cbc068cd0122b1b
https://pubmed.ncbi.nlm.nih.gov/12107413
https://pubmed.ncbi.nlm.nih.gov/12107413
Autor:
Graeme, Wistow, Steven L, Bernstein, M Keith, Wyatt, Sugata, Ray, Amita, Behal, Jeffrey W, Touchman, Gerald, Bouffard, Don, Smith, Katherine, Peterson
Publikováno v:
Molecular vision. 8
Expressed sequence tag (EST) analysis was performed on un-normalized, unamplified cDNA libraries constructed from adult human retina to examine the expression profile of the tissue and to contribute resources for functional genomics studies.Two size
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::feba8c587a93e72b025363e98fd26a42
https://pubmed.ncbi.nlm.nih.gov/12107411
https://pubmed.ncbi.nlm.nih.gov/12107411
Autor:
Graeme, Wistow, Steven L, Bernstein, M Keith, Wyatt, Robert N, Fariss, Amita, Behal, Jeffrey W, Touchman, Gerald, Bouffard, Don, Smith, Katherine, Peterson
Publikováno v:
Molecular vision. 8
The retinal pigment epithelium (RPE) and choroid comprise a functional unit of the eye that is essential to normal retinal health and function. Here we describe expressed sequence tag (EST) analysis of human RPE/choroid as part of a project for ocula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2856d324c39a99827630d695c9c2b46a
https://pubmed.ncbi.nlm.nih.gov/12107410
https://pubmed.ncbi.nlm.nih.gov/12107410
Autor:
Graeme, Wistow, Steven L, Bernstein, Jeffrey W, Touchman, Gerald, Bouffard, M Keith, Wyatt, Katherine, Peterson, Amita, Behal, James, Gao, Patee, Buchoff, Don, Smith
Publikováno v:
Molecular vision. 8
NEIBank is a project to develop and organize genomics and bioinformatics resources for the eye. As part of this effort, tools have been developed for bioinformatics analysis and web based display of data from expressed sequence tag (EST) analyses. ES
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::99278d6722db575d91608b7b9b0980df
https://pubmed.ncbi.nlm.nih.gov/12107414
https://pubmed.ncbi.nlm.nih.gov/12107414
Autor:
Debasish Sinha, Cynthia Jaworski, W. Gerald Robison, Jack Favor, Mary Lyon, Caroline Thaung, Graeme Wistow, Christine Slingsby, M. Keith Wyatt, Lewis K. Pannell, Robert Sarra
Publikováno v:
The Journal of biological chemistry. 276(12)
In Opj, an inherited cataract in mice, opacity is associated with a mutation in Crygs, the gene for gammaS-crystallin, the first mutation to be associated with this gene. A single base change causes replacement of Phe-9, a key hydrophobic residue in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9e63ef63878bdce8c4899d0e57ca188
https://pubmed.ncbi.nlm.nih.gov/11121426
https://pubmed.ncbi.nlm.nih.gov/11121426
Autor:
Lila H. Overby, Christine P. Biagini, Geraldine T. Carver, M. Keith Wyatt, Richard M. Philpot, Kiyoshi Itagaki
Publikováno v:
Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes ISBN: 9781461372028
Humans are exposed on a more or less continual basis to a myriad of synthetic and natural chemicals with the potential to cause deleterious effects. Most exogenous chemi cals undergo oxidative metabolism as a prelude to excretion. This “biotransfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e13637f885f01f987c658e5a337921e
https://doi.org/10.1007/978-1-4615-4855-3_5
https://doi.org/10.1007/978-1-4615-4855-3_5
Autor:
Maria M Campos, Graeme Wistow, Steven L. Bernstein, M. Keith Wyatt, Cynthia Jaworski, Jen-Yue Tsai, Sanghamitra Mishra, Robert N. Fariss
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e68088 (2013)
PLoS ONE
PLoS ONE
Age-related macular degeneration (AMD) is a major cause of vision loss. It is associated with development of characteristic plaque-like deposits (soft drusen) in Bruch's membrane basal to the retinal pigment epithelium (RPE). A sequence variant (Y402
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd2da9cd31a87f2ded883dcf012ef2ab
https://doi.org/10.1371/journal.pone.0068088
https://doi.org/10.1371/journal.pone.0068088