Zobrazeno 1 - 10
of 297
pro vyhledávání: '"M. Kata"'
Publikováno v:
Journal of Inclusion Phenomena. 47:15-23
The effects of hydroxypropyl-β-cyclodextrin and methyl-β-cyclodextrin on the solubility of ketoconazole were studied. Products were prepared by physical mixing, kneading and spray-drying methods in four molecular ratios. Kneaded products in a ratio
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Journal of Neural Transmission. 107:1369-1379
The study examined the effect of pramipexole (2-amino-4,5,6,7-tetrahydro-6-propyl-aminobenzthiazole dihydrochloride; PRA), a new potent dopamine receptor agonist with the high preference for D3 receptors, as compared to D2 or D4, on the central dopam
Publikováno v:
Journal of Inclusion Phenomena and Macrocyclic Chemistry. 34:39-48
A freeze-drying method was used to prepare complexes of furosemide (guest) with three derivatives of β-cyclodextrin (hosts) in different molecular ratios in order to increase the aqueous solubility and rate of dissolution of the drug, and also to st
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 55:115-122
Solid formulas obtained between furosemide and two β-cyclodextrin derivatives (HP-β-CD and RAMEB) were prepared by different methods and in various ratios (1:1 and 1:2). The inclusion complex formation between the drug and the β-CDs of 1:1 ratio w
Publikováno v:
Journal of Inclusion Phenomena and Molecular Recognition in Chemistry. 31:189-196
Furosemide (F) is practically insoluble in water (10.26 mg/100 mL).Different β-cyclo- dextrins (β-CD derivatives) were applied ashost to improve the solubility of furosemide as guest molecule via inclusioncomplex formation. Various molar ratios of
Publikováno v:
Journal of Thermal Analysis. 48:503-514
Solid inclusion complexes of TolperisoneHCl with five various cyclodextrins were prepared by kneading and spray drying. The complex formation between the drug and the cyclodextrins were proven using thermoanalytical methods, X-ray diffraction, IR spe
Publikováno v:
Journal of Inclusion Phenomena and Molecular Recognition in Chemistry. 25:145-148
Publikováno v:
Journal of Inclusion Phenomena and Molecular Recognition in Chemistry. 20:241-252
The incidence of genetic lipoprotein disorders, or hyperlipoproteinaemia, is currently increasing. Examinations were carried out on the hyperlipoproteinaemic drug fenofibrate and various cyclodextrin derivatives were applied to increase the solubilit
Publikováno v:
European Journal of Pharmaceutical Sciences. 1:291-296
Phase solubility diagrams have been used to investigate complexation between 2-hydroxypropyl-β-cyclodextrin (HPBCD) and glibenclamide (GM) in aqueous medium. More stable GM-HPBCD complexes were formed in alkaline medium (in which the drug is in ioni