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Glucocorticoids enhance the potency of Schwann cell mitogens

Autor: O. Kalimi, W. Regelson, G. H. De Vries, T. J. Neuberger, M. Kalimi

Publikováno v: Journal of Neuroscience Research. 38:300-313

Previous studies have documented that cultured Schwann cells require serum-containing medium to respond maximally to mitogens. We now report that Schwann cells are able to proliferate to a mitogenic response in a serum-free defined medium termed olig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9902ade4806222482f037fe294986f94
https://doi.org/10.1002/jnr.490380308

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Heat shock preconditioning and pretreatment with glucocorticoid antagonist RU 486 protect rat myogenic cells H9c2 against glutamate-induced cell death

Autor: E, Gursoy, A, Cardounel, M, Kalimi

Publikováno v: Molecular and cellular biochemistry. 220(1-2)

We have observed that the treatment of rat-heart derived H9c2 myoblasts for 20 h with the excitatory amino acid glutamate resulted in cell death in a dose dependent manner as determined by LDH release. The optimum cardiotoxicity was seen at 25 mM glu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::67872a12653f4643753bc2586f0350d3
https://pubmed.ncbi.nlm.nih.gov/11451379

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Pregnenolone protects mouse hippocampal (HT-22) cells against glutamate and amyloid beta protein toxicity

Autor: E, Gursoy, A, Cardounel, M, Kalimi

Publikováno v: Neurochemical research. 26(1)

In the present work we have examined whether the neurosteroid pregnenolone has any neuroprotective effects against glutamate and amyloid beta protein neurotoxicity using immortalized clonal mouse hippocampal cell line (HT-22). The neurosteroid pregne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c42d46a2531b9ea8c930e3f07108cd5e
https://pubmed.ncbi.nlm.nih.gov/11358277

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Dehydroepiandrosterone protects hippocampal neurons against neurotoxin-induced cell death: mechanism of action

Autor: A, Cardounel, W, Regelson, M, Kalimi

Publikováno v: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 222(2)

Dehydroepiandrosterone (DHEA), an adrenal cortex hormone secreted in large quantities in humans, protects cells of the clonal mouse hippocampal cell line HT-22 against the excitatory amino acid glutamate (5 mM), and amyloid beta-protein (2 microM) to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::684cee8002d8a187320824069fc100da
https://pubmed.ncbi.nlm.nih.gov/10564538

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Identification and characterization of a novel synthetic cannabinoid CP 55,940 binder in rat brain cytosol

Autor: J, Qureshi, M, Saady, A, Cardounel, M, Kalimi

Publikováno v: Molecular and cellular biochemistry. 181(1-2)

We have detected the presence of a specific [3H] CP 55,940 binder in the cytosol of rat cerebral cortex. Competition studies showed that only cold CP 55,940 and to a lesser extent delta9THC was able to compete with [3H] CP 55,940; little competition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::baf7bedbccdb6ce9f9394b97c9466c74
https://pubmed.ncbi.nlm.nih.gov/9562238

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