Zobrazeno 1 - 10
of 54
pro vyhledávání: '"M. K. Raghuraman"'
Publikováno v:
PLoS Genetics, Vol 20, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/7b5fd2de7d7548078a310681a438610e
Autor:
Rebecca Martin, Claudia Y. Espinoza, Christopher R. L. Large, Joshua Rosswork, Cole Van Bruinisse, Aaron W. Miller, Joseph C. Sanchez, Madison Miller, Samantha Paskvan, Gina M. Alvino, Maitreya J. Dunham, M. K. Raghuraman, Bonita J. Brewer
Publikováno v:
PLoS Genetics, Vol 20, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/442bff6d3b6e4116bbcefd688a9e16f1
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 9, Pp 2829-2838 (2016)
The Saccharomyces cerevisiae ribosomal DNA (rDNA) locus is known to exhibit greater instability relative to the rest of the genome. However, wild-type cells preferentially maintain a stable number of rDNA copies, suggesting underlying genetic control
Externí odkaz:
https://doaj.org/article/cb66e24a57e74a2d88139da6632bfdb5
Autor:
Remington E Hoerr, Alex Eng, Celia Payen, Sara C Di Rienzi, M K Raghuraman, Maitreya J Dunham, Bonita J Brewer, Katherine L Friedman
Publikováno v:
GENETICS. 224
Evolution is driven by the accumulation of competing mutations that influence survival. A broad form of genetic variation is the amplification or deletion of DNA (≥50 bp) referred to as copy number variation (CNV). In humans, CNV may be inconsequen
Autor:
Joseph C Sanchez, Elizabeth X Kwan, Thomas J Pohl, Haley M Amemiya, M K Raghuraman, Bonita J Brewer
Publikováno v:
PLoS Genetics, Vol 13, Iss 10, p e1007041 (2017)
A form of dwarfism known as Meier-Gorlin syndrome (MGS) is caused by recessive mutations in one of six different genes (ORC1, ORC4, ORC6, CDC6, CDT1, and MCM5). These genes encode components of the pre-replication complex, which assembles at origins
Externí odkaz:
https://doaj.org/article/c428286c82bd4029ae1c65b1892d6f21
Autor:
Remington E. Hoerr, Alex Eng, Celia Payen, Sara C. Di Rienzi, M. K. Raghuraman, Maitreya J. Dunham, Bonita J. Brewer, Katherine L. Friedman
Evolution is driven by the accumulation of competing mutations that influence survival. A broad form of genetic variation is the amplification or deletion of DNA (≥50 bp) referred to as copy number variation. In humans, copy number variation may be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f01d7894fa01806a081c5bc2420639c
https://doi.org/10.1101/2022.06.12.495855
https://doi.org/10.1101/2022.06.12.495855
GC-rich DNA elements enable replication origin activity in the methylotrophic yeast Pichia pastoris.
Autor:
Ivan Liachko, Rachel A Youngblood, Kyle Tsui, Kerry L Bubb, Christine Queitsch, M K Raghuraman, Corey Nislow, Bonita J Brewer, Maitreya J Dunham
Publikováno v:
PLoS Genetics, Vol 10, Iss 3, p e1004169 (2014)
The well-studied DNA replication origins of the model budding and fission yeasts are A/T-rich elements. However, unlike their yeast counterparts, both plant and metazoan origins are G/C-rich and are associated with transcription start sites. Here we
Externí odkaz:
https://doaj.org/article/58e66a41b5c84c4daf1e96c63c2620b9
Autor:
Maria Naushab, M. K. Raghuraman, Madison Miller, Seung-been Lee, Kelsey L. Lynch, Josh T. Cuperus, Xiaobin S. Wang, Joseph C. Sanchez, Bonita J. Brewer, Haley M. Amemiya, Paula F. Levan, Christine Queitsch, Mackenzie Croy, Elizabeth X. Kwan, Gina M. Alvino, Sarah A. Johnson
Eukaryotes maintain hundreds of copies of ribosomal DNA (rDNA), many more than required for ribosome biogenesis, suggesting a yet undefined role for large rDNA arrays outside of ribosomal RNA synthesis. We demonstrate that reducing the Saccharomyces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fd1fbef8a791125112761bb2c68fd00
https://doi.org/10.1101/2021.02.25.432950
https://doi.org/10.1101/2021.02.25.432950
Autor:
Elizabeth X Kwan, Eric J Foss, Scott Tsuchiyama, Gina M Alvino, Leonid Kruglyak, Matt Kaeberlein, M K Raghuraman, Bonita J Brewer, Brian K Kennedy, Antonio Bedalov
Publikováno v:
PLoS Genetics, Vol 9, Iss 3, p e1003329 (2013)
Aging and longevity are complex traits influenced by genetic and environmental factors. To identify quantitative trait loci (QTLs) that control replicative lifespan, we employed an outbred Saccharomyces cerevisiae model, generated by crossing a viney
Externí odkaz:
https://doaj.org/article/356236c712c8426c8604962fc9490be9
Publikováno v:
PLoS Genetics, Vol 8, Iss 5, p e1002677 (2012)
The centromeric regions of all Saccharomyces cerevisiae chromosomes are found in early replicating domains, a property conserved among centromeres in fungi and some higher eukaryotes. Surprisingly, little is known about the biological significance or
Externí odkaz:
https://doaj.org/article/3756547bed994ea58590eb145d5b825d