Zobrazeno 1 - 10
of 13
pro vyhledávání: '"M. K. Moi"'
Autor:
C F, Meares, M K, Moi, H, Diril, D L, Kukis, M J, McCall, S V, Deshpande, S J, DeNardo, D, Snook, A A, Epenetos
Publikováno v:
The British journal of cancer. Supplement. 10
Monoclonal antibody technology allows the specificity of an antibody for its antigen to be used in targeting cancer cells. Stable attachment of metal ions to antibodies by means of 'bifunctional' chelating agents can add the nuclear, physical and che
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 31(4)
Yttrium-90 (90Y) is a promising radiometal for therapy of cancer due to its high-energy beta emission and a physical half-life of 2.67 days. Bifunctional chelating agents based on DTPA cyclic anhydride or EDTA do not form Y(III) complexes that are st
Publikováno v:
Cancer research. 50
Monoclonal antibody technology allows the specificity of an antibody for its antigen to be used in targeting cancer cells. The conjugation of metals, particularly radionuclides such as 90Y or 67Cu, to monoclonal antibodies results in agents for radio
Publikováno v:
Frontiers of radiation therapy and oncology. 24
Publikováno v:
Journal of Heterocyclic Chemistry. 22:433-435
A series of substituted 2-pyrones and 5,6-dihydropyrones have been synthesized and investigated for their inhibitory activity toward human leukocyte elastase, procine pancreatic elastase and chymotrypsin.
Autor:
Michael J. Brubaker, Robert T. Carroll, M. K. Moi, Michael A. Stanga, T. L. Huang, William C. Groutas
Publikováno v:
Journal of medicinal chemistry. 28(8)
Several congeners of elasnin (I) have been synthesized and shown to inhibit human leukocyte elastase (HLE). The C-3 alkyl substituted 2-pyrones 11 and 12 were found to be the most effective inhibitors of the enzyme. These compounds are highly specifi
Autor:
Michael J. Brubaker, William C. Groutas, M. K. Moi, Michael A. Stanga, T. L. Huang, Robert T. Carroll
Publikováno v:
Chemischer Informationsdienst. 16
Several congeners of elasnin (I) have been synthesized and shown to inhibit human leukocyte elastase (HLE). The C-3 alkyl substituted 2-pyrones 11 and 12 were found to be the most effective inhibitors of the enzyme. These compounds are highly specifi
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 29(2)
Copper-67 (67Cu) is one of the most promising radiometals for radioimmunotherapy because of its 61.5 hr physical half-life, abundant beta particles, and gamma emissions suitable for imaging. However, 67Cu is readily transferred from the usual chelate
Autor:
William C. Groutas, Brubaker Mj, R. C. Badger, K. E. Miller, S. A. Rude, M. K. Moi, M. C. Theodorakis, A. M. Kasper, W. R. Abrams, T. D. Ocain
Publikováno v:
Journal of medicinal chemistry. 28(2)
Several amino acid derived azolides (I) have been synthesized and investigated for their inhibitory activity toward human leukocyte elastase and porcine pancreatic elastase. The inhibitory activity was found to be dependent on the nature of the precu
Autor:
R. C. Badger, K. S. Davis, William C. Groutas, K. E. Miller, A. M. Kasper, W. R. Abrams, M. K. Moi, Michael J. Brubaker, M. E. Zandler, S. A. Rude, T. D. Ocain, M. C. Theodorakis
Publikováno v:
Chemischer Informationsdienst. 16