Zobrazeno 1 - 10
of 11
pro vyhledávání: '"M. K. Korsakov"'
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 13, Iss 3, Pp 219-230 (2024)
Introduction. The study of the systemic exposure of a new original drug is an essential part of its preclinical study. 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide is a new selective carbonic anhydrase II inhibitor for the treatment o
Externí odkaz:
https://doaj.org/article/52838cbd2d95414faabcc41820fa7e0e
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 14, Iss 3, Pp 304-316 (2024)
INTRODUCTION. Systemic exposure studies of a selective carbonic anhydrase II inhibitor, the isoxazole derivative 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide (TFISA), require evaluating its pharmacokinetics in whole blood because the
Externí odkaz:
https://doaj.org/article/5378cde63e634d08b90e1bdf210283a2
Autor:
A. L. Khokhlov, I. I. Yaichkov, M. K. Korsakov, I. N. Kagramanyan, N. N. Volkhin, S. S. Petukhov, V. E. Zaikova
Publikováno v:
Acta Biomedica Scientifica, Vol 9, Iss 1, Pp 177-191 (2024)
Background. Determining changes in the content of monoamine neurotransmitters and their metabolites in brain structures is a necessary part of studying the pharmacodynamics of antiparkinsonian drugs. A method for the joint determination of norepineph
Externí odkaz:
https://doaj.org/article/a09aee0671c34e3a8eb3a3cf56e928e8
Autor:
A. L. Khokhlov, I. I. Yaichkov, A. A. Shetnev, S. A. Ivanovskiy, M. K. Korsakov, O. A. Gasilina, N. N. Volkhin, S. S. Petukhov
Publikováno v:
Фармация и фармакология (Пятигорск), Vol 11, Iss 3, Pp 240-254 (2023)
The aim of the study was to determine biotransformation products of a new selective carbonic anhydrase II inhibitor – 4-(2-methyl-1,3-oxazole-5-yl)-benzenesulfonamide.Materials and methods. The study was conducted on 3 Wistar rats and 3 rabbits of
Externí odkaz:
https://doaj.org/article/c01fc731c31848b58076c4d688b66666
Autor:
V. N. Fedorov, V. P. Vdovichenko, M. K. Korsakov, V. V. Strakhov, A. A. Popova, A. I. Khokhlov, S. S. Suleymanov
Publikováno v:
Качественная клиническая практика, Vol 0, Iss 3, Pp 44-54 (2023)
Glaucoma is a disease associated with increased intraocular pressure (IOP). Of the pharmacological agents for treating glaucoma, there are drugs of the first (most effective and safe) and second-line treatment. First-line treatment includes prostagla
Externí odkaz:
https://doaj.org/article/47206004a0874c06b29c77e6c0fc7d35
Publikováno v:
Russian Journal of General Chemistry. 92:2982-2988
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e7fcd88ef8f23babd7c1b83f5e42c98
https://doi.org/10.1134/s1070363222120568
https://doi.org/10.1134/s1070363222120568
Autor:
Aleksandr Kotov, A. A. Shetnev, M. K. Korsakov, Irina K. Proskurina, V. E. Pankratieva, A. S. Vlasov, A. S. Kunichkina
Publikováno v:
Russian Journal of Organic Chemistry. 56:1181-1186
A new procedure has been proposed for the synthesis of 3,5-disubstituted 1,2,4-oxadiazoles by reaction of amidoximes with aldehydes in the superbasic system NaOH/DMSO at room temperature. The scope of the proposed procedure has been demonstrated by 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1461619a8d8157eed9b62aefe2aeccbe
https://doi.org/10.1134/s107042802007009x
https://doi.org/10.1134/s107042802007009x
Publikováno v:
Вестник Башкирского университета. :763
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::631ef5ae381584ae6842fc2459be038f
https://doi.org/10.33184/bulletin-bsu-2020.4.10
https://doi.org/10.33184/bulletin-bsu-2020.4.10
Publikováno v:
Journal of Organic and Pharmaceutical Chemistry. 11:38-41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::945dab39acd5cb74291acdd4ce153046
https://doi.org/10.24959/ophcj.13.765
https://doi.org/10.24959/ophcj.13.765
Autor:
Yu. A. Kovygin, Kh. S. Shikhaliev, Zh. V. Chirkova, M. K. Korsakov, Igor G. Abramov, Sergei I. Filimonov, Sergey I. Firgang, G. A. Stashina
Publikováno v:
Chemistry of Heterocyclic Compounds. 49:993-999
Substituted 5-amino-4-arylpyrazoles on condensation with itaconic acid form substituted tetrahydropyrazolo[1,5-a]pyrimidines, and on condensation with maleic anhydride form 2,3-dihydro-1H-imidazolo[1,2-b]pyrazoles, which on more extended heating rear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c75329710f1be5003f571429ec2acedd
https://doi.org/10.1007/s10593-013-1337-7
https://doi.org/10.1007/s10593-013-1337-7