Výsledky vyhledávání - "M. K. Khanina"

[Immunogenicity and stability of a Soviet inactivated cultured vaccine against Japanese encephalitis]

Autor: M K, Khanina, N G, Bochkova, V P, Grachev, L B, El'bert, M S, Vorob'eva, E A, Borsuk, V V, Pogodina

Publikováno v: Voprosy virusologii. 35(6)

Six immunologically active vaccine batches inducing a specific antibody to Japanese encephalitis (JE) virus were obtained in serial manufacture of the preparation. In HI tests, the minimal antibody titre was 1:80, the maximal 1:320, neutralization in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3ed9d43b79c1cb27bd99136b9c423813
https://pubmed.ncbi.nlm.nih.gov/2082551

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Comparative study of infectious and formaldehyde-inactivated tick-borne encephalitis virus particles

Autor: S. G. Sobolev, M. K. Khanina, L. B. Elbert, I. V. Krasilnikov

Publikováno v: Archives of Virology. 79:241-253

The structure and properties of infectious and formaldehyde-treated particles of tick-borne encephalitis virus, concentrated and purified by chromatography on macroporous glass, were studied. In addition to complete virions, such preparations contain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a265ac94ef7938d1ac35d0ade25fe633
https://doi.org/10.1007/bf01310814

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[RAMT cell line as a substrate for the propagation of vaccinal viral strains]

Autor: V P, Grachev, M A, Zaval'nyĭ, V D, Popova, M K, Khanina, G P, Baranova

Publikováno v: Voprosy virusologii. 31(6)

Properties of the PAMT cell line which are deficient in hypoxanthine guanyl phosphoribosiltransferase were studied. The PAMT cell line derived from African green monkey kidney tissue may be identified by selective nutrient media, contains no contamin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a651747f0d54ad45cafc65526af5486
https://pubmed.ncbi.nlm.nih.gov/3825095

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[Chromatography of formalin-inactivated tick-borne encephalitis viruses on macroporous glass]

Autor: L B, El'bert, I V, Krasil'nikov, B V, Mchedlishvili, V M, Kolikov, M K, Khanina

Publikováno v: Voprosy virusologii. (1)

The results of further development of methods for chromatographic concentration and purification of tick-borne encephalitis virus on columns with porous glass using formalin-inactivated virus suspensions are presented. The method of adsorption chroma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::210e39a84d00c989546aa945c9d15e8e
https://pubmed.ncbi.nlm.nih.gov/7257326

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[Concentrated purified vaccine against tick-borne encephalitis prepared by means of zonal ultracentrifugation. Development of the preparation]

Autor: L B, El'bert, A V, Gagarina, M K, Khanina, G L, Krutianskaia, V P, Grachev

Publikováno v: Voprosy virusologii. (3)

A concentrated and purified (lyophilized) preparation with a high immunological activity was obtained from formalin-inactivated tissue culture suspensions of tick-borne encephalitis (TBE) virus. Its high immunogenicity was demonstrated in mouse prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6d66ccee6c9ed025e08fbfa6038c898e
https://pubmed.ncbi.nlm.nih.gov/7434727

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[Comparison of methods for the large-scale culture of cells and viruses]

Autor: V P, Grachev, M A, Zaval'nyĭ, V D, Popova, M K, Khanina, L L, Mironova

Publikováno v: Voprosy virusologii. 28(4)

The paper presents the results of experiments on propagation of primary, secondary, and continuous diploid and heteroploid human and animal cells in 2 different systems for large-scale propagation: in perfusion tank with Rashig rings and in tanks wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::03d01b1d438a365d2d8b7318e353581d
https://pubmed.ncbi.nlm.nih.gov/6314668

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